Mouse anti Pan Keratin (4 antibody5 antibody6 antibody8 antibody10 antibody13 antibody18)
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Catalog number
X1260M
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Price
Please ask
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Size
100 μg
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Category
Primary Antibodies
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Long description
Cytokeratins (CK) are intermediate filaments of epithelial cells, both in keratinizing tissue (ie., skin) and non-keratinizing cells (ie., mesothelial cells). Although not a traditional marker for endothelial cells, cytokeratins have also been found in some microvascular endothelial cells. Atleast 20 different cytokeratins (CK) in the molecular range of 40-70 kDa and isoelectric points of 5-8.5 can be identified using two dimensional gel electrophoresis. Biochemically, most members of the CK family fall into one of two classes, type I (acidic polypeptides) and type II (basic polypeptides). At least one member of the acidic family and one member of the basic family is expressed in all epithelial cells. Monoclonal antibodies to cytokeratin proteins can be useful markers for tumor identification and classification._x000B__x000B_Reacting with a variety of keratins (4,5,6,8,10,13 and 18) which reacts with a variety of normal reactive and neoplasmic epithelia. Reacting with simple epithelium and both basal and superbasal layers of comfying and non comfying squamous epithelium this antibody is also useful in staining cultured epithelial cell lines. It is useful in differentiating epithelial tumors from non-epithelial tumors.
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Antibody come from
n/a
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Other description
Provided as solution in Laemmli electrophoresis sample buffer. Samples need to be boiled for 3-5 minutes, before loading the gel. Protein A/G Chromatography
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Clone
C11
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Antigen antibody binding interaction
Mouse anti Pan Keratin (4 antibody5 antibody6 antibody8 antibody10 antibody13 antibody18) Antibody
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Antibody is raised in
Mouse
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Antibody s reacts with
Human
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Antibody s reacts with these species
This antibody doesn't cross react with other species
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Antibody s specificity
No Data Available
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Application
Western Blot, Immunohistochemistry (Frozen & Paraffin Sections)
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Antibody s suited for
Suggested use: A volume of 10-25ul is suggested for immunobloting. Optimal concentration should be evaluated by serial dilutions.
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Storage
-20ºC
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Relevant references
no information yet
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Protein number
see ncbi
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Warnings
This product is intended FOR RESEARCH USE ONLY, and FOR TESTS IN VITRO, not for use in diagnostic or therapeutic procedures involving humans or animals. This datasheet is as accurate as reasonably achievable, but Nordic-MUbio accepts no liability for any inaccuracies or omissions in this information.
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Description
This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided.
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Test
Mouse or mice from the Mus musculus species are used for production of mouse monoclonal antibodies or mabs and as research model for humans in your lab. Mouse are mature after 40 days for females and 55 days for males. The female mice are pregnant only 20 days and can give birth to 10 litters of 6-8 mice a year. Transgenic, knock-out, congenic and inbread strains are known for C57BL/6, A/J, BALB/c, SCID while the CD-1 is outbred as strain.
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Latin name
Mus musculus
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Gene target
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Short name
Mouse anti Pan Keratin (4 antibody5 antibody6 antibody8 antibody10 antibody13 antibody18)
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Technique
Mouse, anti, antibody to, mouses
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Host
mouse
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Isotype
IgG1
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Label
unlabeled
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Species
Mouse, Mouses
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Alternative name
Mouse antibody to Pan Keratin (4 antibody5 antibody6 antibody8 antibody10 antibody13 antibody18)
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Alternative technique
murine, antibodies
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MeSH Data
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Name
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Concept
Scope note:
Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
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Tree numbers
- E05.196.401.143
- E05.301.300.096
- E05.478.566.320.200
- E05.601.262
- E05.601.470.320.200
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Qualifiers
ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data
Product images
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