PROX1 Antibody
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Catalog numberF53186-0.08ML
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PricePlease ask
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Size0.08 ml
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CategoryAntibody
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ConcentrationIn 1X PBS, pH 7.4, with 0.09% sodium azide
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FormAntigen affinity purified
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ConjugationUnconjugated
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ClonePolyclonal antibody
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Recognised antigenPROX1
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Host animalRabbit (Oryctolagus cuniculus)
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ClonalityPolyclonal (rabbit origin)
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Species reactivityHuman (Homo sapiens), Mouse (Mus musculus) ; Due to limited knowledge and inability to test the antibody against all known species, we cannot guarantee that no other cross reactivity can occur.
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Tested applicationsWB, ELISA
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Recommended dilutionsWestern blot: 1:1000-2000
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NotesTitration of the PROX1 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
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Intented useThis PROX1 antibodyis to be used only for research purposes and not for diagnostics..
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UniprotQ92786
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PurityAntigen affinity
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DescriptionTranscription factor involved in developmental processes such as cell fate determination, gene transcriptional regulation and progenitor cell regulation in a number of organs. Plays a critical role in embryonic development and functions as a key regulatory protein in neurogenesis and the development of the heart, eye lens, liver, pancreas and the lymphatic system. Involved in the regulation of the circadian rhythm. Represses: transcription of the retinoid-related orphan receptor RORG, transcriptional activator activity of RORA and RORG and the expression of RORA/G-target genes including core clock components: ARNTL/BMAL1, NPAS2 and CRY1 and metabolic genes: AVPR1A and ELOVL3.
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ImmunogenThis PROX1 antibody was produced from a rabbit immunized with a KLH conjugated synthetic peptide between 444-478 amino acids from the Central region of human PROX1.
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StorageAliquot the PROX1 antibody and store frozen at -20 deg. Celcius or lower. Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity. Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized.
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PropertiesIf you buy Antibodies supplied by NJS poly they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
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French translationanticorps
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Gene target
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Gene symbolPROX1, PROX1-AS1
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Short nameAnti-PROX1
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TechniqueAntibody, antibodies against human proteins, antibodies for
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IsotypeRabbit Ig
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Alternative nameAntibodies to PROX1
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Alternative techniqueantibodies
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Alternative to gene targetprospero homeobox 1, PROX1 and IDBG-106631 and ENSG00000117707 and 5629, LBD domain binding, nuclei, Prox1 and IDBG-208536 and ENSMUSG00000010175 and 19130, PROX1 and IDBG-638014 and ENSBTAG00000010978 and 515324
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Gene info
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Identity
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Gene
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Long gene nameprospero homeobox 1
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Synonyms gene name
- prospero-related homeobox 1
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GenBank acession
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Locus
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Discovery year1998-05-18
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- PROS class homeoboxes
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VEGA ID
Gene info
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Identity
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Gene
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Long gene namePROX1 antisense RNA 1
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Synonyms gene name
- PROX1 antisense RNA 1 (non-protein coding)
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GenBank acession
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Locus
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Discovery year2012-01-23
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Entrez gene record
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RefSeq identity
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Classification
- Antisense RNAs
MeSH Data
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Name
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ConceptScope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
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Tree numbers
- E05.196.401.143
- E05.301.300.096
- E05.478.566.320.200
- E05.601.262
- E05.601.470.320.200
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Qualifiersethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data