BMPR1B Antibody

• Catalog number
  F47734-0.08ML
• Price
  Please ask
• Size
  0.08 ml

• Category
  Antibody
• Concentration
  In 1X PBS, pH 7.4, with 0.09% sodium azide
• Form
  Purified
• Conjugation
  Unconjugated
• Clone
  Polyclonal antibody
• Recognised antigen
  BMPR1B
• Host animal
  Rabbit (Oryctolagus cuniculus)
• Clonality
  Polyclonal (rabbit origin)
• Species reactivity
  Human (Homo sapiens), Mouse (Mus musculus) ; Due to limited knowledge and inability to test the antibody against all known species, we cannot guarantee that no other cross reactivity can occur.
• Tested applications
  WB, ELISA
• Recommended dilutions
  Western blot: 1:1000
• Notes
  Titration of the BMPR1B antibody may be required due to differences in protocols and secondary/substrate sensitivity.
• Intented use
  This BMPR1B antibodyis to be used only for research purposes and not for diagnostics..
• Uniprot
  O00238
• Purity
  Purified
• Description
  The bone morphogenetic protein (BMP) receptors are a family of transmembrane serine/threonine kinases that include the type I receptors BMPR1A and BMPR1B and the type II receptor BMPR2. These receptors are also closely related to the activin receptors, ACVR1 and ACVR2. The ligands of these receptors are members of the TGF-beta superfamily. TGF-betas and activins transduce their signals through the formation of heteromeric complexes with 2 different types of serine (threonine) kinase receptors: type I receptors of about 50-55 kD and type II receptors of about 70-80 kD. Type II receptors bind ligands in the absence of type I receptors, but they require their respective type I receptors for signaling, whereas type I receptors require their respective type II receptors for ligand binding.
• Immunogen
  A portion of amino acids 1-30 from the human protein was used as the immunogen for this BMPR1B antibody.
• Storage
  Aliquot the BMPR1B antibody and store frozen at -20 deg. Celcius or lower. Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity. Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized.
• Properties
  If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• French translation
  anticorps

• Gene target
  BMPR1B  
• Gene symbol
  BMPR1B-DT, BMPR1B
• Short name
  Anti-BMPR1B
• Technique
  Antibody, antibodies against human proteins, antibodies for
• Isotype
  Rabbit Ig
• Alternative name
  Antibodies to BMPR1B
• Alternative technique
  antibodies
• Alternative to gene target
  bone morphogenetic protein receptor, type IB, ALK-6 and ALK6 and CDw293, BMPR1B and IDBG-30667 and ENSG00000138696 and 658, transforming growth factor beta receptor activity, Plasma membranes, Bmpr1b and IDBG-196928 and ENSMUSG00000052430 and 12167, BMPR1B and IDBG-641011 and ENSBTAG00000002081 and 407128

Gene info

• Identity
  HGNC:50864
• Gene
  BMPR1B-DT
• Long gene name
  BMPR1B divergent transcript
• Synonyms gene
  • BMPR1B-AS1
• Synonyms gene name
  • BMPR1B antisense RNA 1 (head to head)
• Synonyms
  • TCONS_00007797
• Locus
  4q22.3
• Discovery year
  2014-07-14
• Entrez gene record
  100507012
• Classification
  • Divergent transcripts
• VEGA ID
  OTTHUMG00000161193

Gene info

• Identity
  HGNC:1077
• Gene
  BMPR1B
• Long gene name
  bone morphogenetic protein receptor type 1B
• Synonyms gene name
  • bone morphogenetic protein receptor, type IB
• Synonyms
  • ALK6
  • CDw293
• GenBank acession
  • D89675
• Locus
  4q22.3
• Discovery year
  1997-03-19
• Entrez gene record
  658
• Pubmed identfication
  • 8140412
  • 9730621
• RefSeq identity
  • NM_001203
• Classification
  • CD molecules
  • Type 1 receptor serine/threonine kinases
• VEGA ID
  OTTHUMG00000130991

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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