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BMPR1B Antibody

  • Catalog number
    F47735-0.4ML
  • Product name
    BMPR1B Antibody
  • Size
    0.4 ml
  • Price
    Ask For Price
  • Contact us
    BMPR1B Antibody
  • Short name
    Anti-BMPR1B
  • Category
    Antibody
  • Concentration
    In 1X PBS, pH 7.4, with 0.09% sodium azide
  • Form
    Purified
  • Conjugation
    Unconjugated
  • Clone
    Polyclonal antibody
  • Recognised antigen
    BMPR1B
  • Host animal
    Rabbit (Oryctolagus cuniculus)
  • Clonality
    Polyclonal (rabbit origin)
  • Isotype
    Rabbit Ig
  • Species reactivity
    Human (Homo sapiens) ; Due to limited knowledge and inability to test the antibody against all known species, we cannot guarantee that no other cross reactivity can occur.
  • Tested applications
    WB, IHC, ELISA
  • Recommended dilutions
    Western blot: 1:1000,IHC (Paraffin): 1:50-1:100
  • Notes
    Titration of the BMPR1B antibody may be required due to differences in protocols and secondary/substrate sensitivity.
  • Intented use
    This BMPR1B antibodyis to be used only for research purposes and not for diagnostics..
  • Uniprot
    O00238
  • Purity
    Purified
  • Description
    The bone morphogenetic protein (BMP) receptors are a family of transmembrane serine/threonine kinases that include the type I receptors BMPR1A and BMPR1B and the type II receptor BMPR2. These receptors are also closely related to the activin receptors, ACVR1 and ACVR2. The ligands of these receptors are members of the TGF-beta superfamily. TGF-betas and activins transduce their signals through the formation of heteromeric complexes with 2 different types of serine (threonine) kinase receptors: type I receptors of about 50-55 kD and type II receptors of about 70-80 kD. Type II receptors bind ligands in the absence of type I receptors, but they require their respective type I receptors for signaling, whereas type I receptors require their respective type II receptors for ligand binding.
  • Immunogen
    A portion of amino acids 472-502 from the human protein was used as the immunogen for this BMPR1B antibody.
  • Storage
    Aliquot the BMPR1B antibody and store frozen at -20 deg. Celcius or lower. Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity. Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized.
  • Alternative to gene target
    • [ "bone morphogenetic protein receptor, type IB", "ALK-6 and ALK6 and CDw293", "BMPR1B and IDBG-30667 and ENSG00000138696 and 658", "transforming growth factor beta receptor activity", "Plasma membranes", "Bmpr1b and IDBG-196928 and ENSMUSG00000052430 and 12167", "BMPR1B and IDBG-641011 and ENSBTAG00000002081 and 407128" ]
  • Gene target
    BMPR1B
    • Gene info
    Gene info
  • Gene symbol
    BMPR1B-DT, BMPR1B
  • isotype filter
    • Rabbit Ig
  • technique filter
    • Antibody
  • Technique
    Antibody, antibodies against human proteins, antibodies for
  • Alternative technique
    antibodies