BMPR1B Antibody

• Catalog number
  F41873-0.4ML
• Price
  Please ask
• Size
  0.4 ml

• Category
  Antibody
• Concentration
  In 1X PBS, pH 7.4, with 0.09% sodium azide
• Form
  Antigen affinity purified
• Conjugation
  Unconjugated
• Clone
  Polyclonal antibody
• Recognised antigen
  BMPR1B
• Host animal
  Rabbit (Oryctolagus cuniculus)
• Clonality
  Polyclonal (rabbit origin)
• Species reactivity
  Human (Homo sapiens) ; Due to limited knowledge and inability to test the antibody against all known species, we cannot guarantee that no other cross reactivity can occur.
• Tested applications
  WB, IHC, ELISA
• Recommended dilutions
  Western blot: 1:1000,IHC (Paraffin): 1:10-1:50
• Notes
  Titration of the BMPR1B antibody may be required due to differences in protocols and secondary/substrate sensitivity.
• Intented use
  This BMPR1B antibodyis to be used only for research purposes and not for diagnostics..
• Uniprot
  O00238
• Purity
  Antigen affinity
• Description
  This gene encodes a member of the bone morphogenetic protein (BMP) receptor family of transmembrane serine/threonine kinases. The ligands of this receptor are BMPs, which are members of the TGF-beta superfamily. BMPs are involved in endochondral bone formation and embryogenesis. These proteins transduce their signals through the formation of heteromeric complexes of 2 different types of serine (threonine) kinase receptors: type I receptors of about 50-55 kD and type II receptors of about 70-80 kD. Type II receptors bind ligands in the absence of type I receptors, but they require their respective type I receptors for signaling, whereas type I receptors require their respective type II receptors for ligand binding. Mutations in this gene have been associated with primary pulmonary hypertension.
• Immunogen
  A portion of amino acids 134-162 from the human protein was used as the immunogen for this BMPR1B antibody.
• Storage
  Aliquot the BMPR1B antibody and store frozen at -20 deg. Celcius or lower. Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity. Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized.
• Properties
  If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• French translation
  anticorps

• Gene target
  BMPR1B  
• Gene symbol
  BMPR1B-DT, BMPR1B
• Short name
  Anti-BMPR1B
• Technique
  Antibody, antibodies against human proteins, antibodies for
• Isotype
  Rabbit Ig
• Alternative name
  Antibodies to BMPR1B
• Alternative technique
  antibodies
• Alternative to gene target
  bone morphogenetic protein receptor, type IB, ALK-6 and ALK6 and CDw293, BMPR1B and IDBG-30667 and ENSG00000138696 and 658, transforming growth factor beta receptor activity, Plasma membranes, Bmpr1b and IDBG-196928 and ENSMUSG00000052430 and 12167, BMPR1B and IDBG-641011 and ENSBTAG00000002081 and 407128

Gene info

• Identity
  HGNC:50864
• Gene
  BMPR1B-DT
• Long gene name
  BMPR1B divergent transcript
• Synonyms gene
  • BMPR1B-AS1
• Synonyms gene name
  • BMPR1B antisense RNA 1 (head to head)
• Synonyms
  • TCONS_00007797
• Locus
  4q22.3
• Discovery year
  2014-07-14
• Entrez gene record
  100507012
• Classification
  • Divergent transcripts
• VEGA ID
  OTTHUMG00000161193

Gene info

• Identity
  HGNC:1077
• Gene
  BMPR1B
• Long gene name
  bone morphogenetic protein receptor type 1B
• Synonyms gene name
  • bone morphogenetic protein receptor, type IB
• Synonyms
  • ALK6
  • CDw293
• GenBank acession
  • D89675
• Locus
  4q22.3
• Discovery year
  1997-03-19
• Entrez gene record
  658
• Pubmed identfication
  • 8140412
  • 9730621
• RefSeq identity
  • NM_001203
• Classification
  • CD molecules
  • Type 1 receptor serine/threonine kinases
• VEGA ID
  OTTHUMG00000130991

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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