Recombinant Leukemia Inhibitory Factor Receptor (LIFR)

• Catalog number
  MBS2009795
• Price
  Please ask
• Size
  0,01 mg

• Other size
  please contact us to order other different size
• Description
  Aplha, transcription related growth factors and stimulating factors or repressing nuclear factors are complex subunits of proteins involved in cell differentiation. Complex subunit associated factors are involved in hybridoma growth, Eosinohils, eritroid proliferation and derived from promotor binding stimulating subunits on the DNA binding complex. NFKB 105 subunit for example is a polypetide gene enhancer of genes in B cells. The receptors are ligand binding factors of type 1, 2 or 3 and protein-molecules that receive chemical-signals from outside a cell. When such chemical-signals couple or bind to a receptor, they cause some form of cellular/tissue-response, e.g. a change in the electrical-activity of a cell. In this sense, am olfactory receptor is a protein-molecule that recognizes and responds to endogenous-chemical signals, chemokinesor cytokines e.g. an acetylcholine-receptor recognizes and responds to its endogenous-ligand, acetylcholine. However, sometimes in pharmacology, the term is also used to include other proteins that are drug-targets, such as enzymes, transporters and ion-channels.
• Source
  Recombinants or rec. proteins
• Group
  recombinants

• Gene target
  Leukemia   Inhibitory   Factor   Receptor   LIFR  
• Gene symbol
  LIFR-AS1, LIFR
• Short name
  Recombinant Leukemia Inhibitory Factor Receptor (LIFR)
• Technique
  Recombinant, E. coli recombinant proteins are genetic recombinations in Escherichia coli, supplied as white sterile powder lyopillized. MyBioSource advises they will be reconstituted in a buffer soluion or culture medium for cell culture.
• Alternative name
  Rec. Leukemia Inhibitory Factor Receptor (leukemia inhibitory factor receptor alpha)
• Alternative technique
  rec
• Alternative to gene target
  leukemia inhibitory factor receptor alpha, CD118 and LIF-R and SJS2 and STWS and SWS, LIFR and IDBG-17489 and ENSG00000113594 and 3977, growth factor binding, Extracellular, Lifr and IDBG-128297 and ENSMUSG00000054263 and 16880, LIFR and IDBG-630017 and ENSBTAG00000010423 and 539504
• Virus
  leukemia

Gene info

• Identity
  HGNC:43600
• Gene
  LIFR-AS1
• Long gene name
  LIFR antisense RNA 1
• Synonyms gene name
  • LIFR antisense RNA 1 (non-protein coding)
• GenBank acession
  • BC038371
• Locus
  5p13.1
• Discovery year
  2011-11-23
• Entrez gene record
  100506495
• Pubmed identfication
  • 26725846
  • 29807108
• Classification
  • Antisense RNAs
• VEGA ID
  OTTHUMG00000162109

Gene info

• Identity
  HGNC:6597
• Gene
  LIFR
• Long gene name
  LIF receptor subunit alpha
• Synonyms gene name
  • leukemia inhibitory factor receptor
  • leukemia inhibitory factor receptor alpha
  • LIF receptor alpha
• Synonyms
  • CD118
• GenBank acession
  • X61615
• Locus
  5p13.1
• Discovery year
  1992-08-24
• Entrez gene record
  3977
• Pubmed identfication
  • 1915266
• RefSeq identity
  • NM_002310
• Classification
  • Fibronectin type III domain containing
  • CD molecules
  • MicroRNA protein coding host genes
• VEGA ID
  OTTHUMG00000131138

MeSH Data

• Name
  Leukemia, Experimental
• Concept
  Scope note: Leukemia induced experimentally in animals by exposure to leukemogenic agents, such as VIRUSES; RADIATION; or by TRANSPLANTATION of leukemic tissues.
• Tree numbers
  • C04.557.337.372
  • C04.619.531
  • E05.598.500.496.500
• Qualifiers
  diagnosis, parasitology, immunology, microbiology, diagnostic imaging, physiopathology, rehabilitation, enzymology, etiology, mortality, epidemiology, blood, cerebrospinal fluid, chemically induced, congenital, diet therapy, drug therapy, therapy, psychology, urine, virology, history, classification, economics, embryology, genetics, nursing, radiotherapy, ethnology, prevention & control, pathology, metabolism, complications, surgery

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