Rat LIFR (Leukemia Inhibitory Factor Receptor) CLIA Kit

• Catalog number
  E-CL-R0417-96T
• Price
  Please ask
• Size
  96Test

• Detection Type
  Colormetric
• Target Species
  Rat
• Target Synonym
  CD118, LIF-R, SJS2, STWS, SWS
• Test principle
  This CLIA kit uses the Sandwich- CLIA principle. The micro CLIA plate provided in this kit has been pre-coated with an antibody specific to Rat LIFR . Standards or samples are added to the micro CLIA plate wells and combined with the specific antibody. Then a biotinylated detection antibody specific for Rat LIFR and Avidin-Horseradish Peroxidase (HRP) conjugate are added successively to each micro plate well and incubated. Free components are washed away. The substrate solution is added to each well. Only those wells that contain Rat LIFR , biotinylated detection antibody and Avidin-HRP conjugate will appear fluorescence. The Relative light unit (RLU) value is measured by the Chemiluminescence immunoassay analyzer. The RLU value is positively associated with the concentration of Rat LIFR . You can calculate the concentration of Rat LIFR in the samples by comparing the RLU value of the samples to the standard curve.
• Sensitivity
  37.5pg/mL
• Detection Range
  62.5~4000pg/mL
• Target Name
  LIFR
• UNIProt ID
  NA
• Tested Sample Types
  Serum, Plasma, Cell supernatant
• Product Name
  Rat LIFR (Leukemia Inhibitory Factor Receptor) CLIA Kit
• Type
  Sandwich
• Technical data
• Standard Curve RUL
• Description
  Aplha, transcription related growth factors and stimulating factors or repressing nuclear factors are complex subunits of proteins involved in cell differentiation. Complex subunit associated factors are involved in hybridoma growth, Eosinohils, eritroid proliferation and derived from promotor binding stimulating subunits on the DNA binding complex. NFKB 105 subunit for example is a polypetide gene enhancer of genes in B cells. The receptors are ligand binding factors of type 1, 2 or 3 and protein-molecules that receive chemical-signals from outside a cell. When such chemical-signals couple or bind to a receptor, they cause some form of cellular/tissue-response, e.g. a change in the electrical-activity of a cell. In this sense, am olfactory receptor is a protein-molecule that recognizes and responds to endogenous-chemical signals, chemokinesor cytokines e.g. an acetylcholine-receptor recognizes and responds to its endogenous-ligand, acetylcholine. However, sometimes in pharmacology, the term is also used to include other proteins that are drug-targets, such as enzymes, transporters and ion-channels.
• About
  Rats are used to make rat monoclonal anti mouse antibodies. There are less rat- than mouse clones however. Rats genes from rodents of the genus Rattus norvegicus are often studied in vivo as a model of human genes in Sprague-Dawley or Wistar rats.
• Latin name
  Rattus norvegicus

• Gene target
  LIFR   Leukemia   Inhibitory   Factor   Receptor   CLIA   Kit  
• Gene symbol
  LIFR-AS1, LIFR
• Short name
  LIFR (Leukemia Inhibitory Factor Receptor) CLIA Kit
• Host
  Rat
• Species
  Rat, Rats
• Alternative name
  Rat leukemia inhibitory factor receptor alpha (Leukemia Inhibitory Factor Receptor) CLIA reagent
• Alternative technique
  kits
• Alternative to gene target
  leukemia inhibitory factor receptor alpha, CD118 and LIF-R and SJS2 and STWS and SWS, LIFR and IDBG-17489 and ENSG00000113594 and 3977, growth factor binding, Extracellular, Lifr and IDBG-128297 and ENSMUSG00000054263 and 16880, LIFR and IDBG-630017 and ENSBTAG00000010423 and 539504
• Virus
  leukemia

Gene info

• Identity
  HGNC:43600
• Gene
  LIFR-AS1
• Long gene name
  LIFR antisense RNA 1
• Synonyms gene name
  • LIFR antisense RNA 1 (non-protein coding)
• GenBank acession
  • BC038371
• Locus
  5p13.1
• Discovery year
  2011-11-23
• Entrez gene record
  100506495
• Pubmed identfication
  • 26725846
  • 29807108
• Classification
  • Antisense RNAs
• VEGA ID
  OTTHUMG00000162109

Gene info

• Identity
  HGNC:6597
• Gene
  LIFR
• Long gene name
  LIF receptor subunit alpha
• Synonyms gene name
  • leukemia inhibitory factor receptor
  • leukemia inhibitory factor receptor alpha
  • LIF receptor alpha
• Synonyms
  • CD118
• GenBank acession
  • X61615
• Locus
  5p13.1
• Discovery year
  1992-08-24
• Entrez gene record
  3977
• Pubmed identfication
  • 1915266
• RefSeq identity
  • NM_002310
• Classification
  • Fibronectin type III domain containing
  • CD molecules
  • MicroRNA protein coding host genes
• VEGA ID
  OTTHUMG00000131138

MeSH Data

• Name
  Leukemia, Experimental
• Concept
  Scope note: Leukemia induced experimentally in animals by exposure to leukemogenic agents, such as VIRUSES; RADIATION; or by TRANSPLANTATION of leukemic tissues.
• Tree numbers
  • C04.557.337.372
  • C04.619.531
  • E05.598.500.496.500
• Qualifiers
  diagnosis, parasitology, immunology, microbiology, diagnostic imaging, physiopathology, rehabilitation, enzymology, etiology, mortality, epidemiology, blood, cerebrospinal fluid, chemically induced, congenital, diet therapy, drug therapy, therapy, psychology, urine, virology, history, classification, economics, embryology, genetics, nursing, radiotherapy, ethnology, prevention & control, pathology, metabolism, complications, surgery

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