Prekallikrein Heavy Chain (Kininogenin, Fletcher factor, KLKB1, KLK3)
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Catalog numberMBS601722
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Price:
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Size5x0.2 mg
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Products_typeAntibody
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Products_short_name[Prekallikrein Heavy Chain]
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Products_name_syn[Anti -Prekallikrein Heavy Chain (Kininogenin, Fletcher factor, KLKB1, KLK3)]
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Other_names[Plasma kallikrein; Plasma kallikrein; plasma kallikrein; kininogenin; Fletcher factor; plasma prekallikrein; plasma kallikrein heavy chain; plasma kallikrein light chain; kallikrein B, plasma (Fletcher factor) 1; Fletcher factor; Kininogenin; Plasma prekallikrein]
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Other_gene_names[KLKB1; KLKB1; PPK; KLK3; KLK3]
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ClonalityMonoclonal
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Clone[1.B.715]
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ReactivityHuman
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SpecificityRecognizes two variants (88kD and 85kD) of human prekallikrein and it's activation products human kallikrein (88kD and 85kD), the complexes formed by kallikrein with its endogenous inhibitors C1 inhibitor, alpha-2-macroglobulin and Antithrombin III, and 45kD prekallikrein/kallikrein fragment(s). Does not cross-react with tissue kallikrein. Recognizes prekallikrein and it's activation products in chimpanzee, Rhesus, and baboon plasmas. The epitope, located on the heavy chain, is involved in the interaction between prekallikrein and factor XIIa.
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PurityAffinity Purified Purified by Protein G chromatography.
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FormSupplied as a liquid in PBS, pH 7.4. No preservative added.
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Storage_stabilityMay be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
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Tested_applicationELISA (EL/EIA), Western Blot (WB)
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DescriptionAplha, transcription related growth factors and stimulating factors or repressing nuclear factors are complex subunits of proteins involved in cell differentiation. Complex subunit associated factors are involved in hybridoma growth, Eosinohils, eritroid proliferation and derived from promotor binding stimulating subunits on the DNA binding complex. NFKB 105 subunit for example is a polypetide gene enhancer of genes in B cells.
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Gene target
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Gene symbolKLKB1, KLK3
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Short namePrekallikrein Heavy Chain (Kininogenin, Fletcher factor, KLKB1, KLK3)
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HostMouse
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IsotypeIgG1
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Alternative namePrekallikrein Heavy epitope (Kininogenin, Fletcher factor, KLKB1, KLK3)
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Gene info
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Identity
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Gene
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Long gene namekallikrein B1
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Synonyms gene
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Synonyms gene name
- kallikrein B, plasma (Fletcher factor) 1
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Synonyms name
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GenBank acession
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Locus
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Discovery year1999-04-23
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- Kallikreins
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VEGA ID
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Locus Specific Databases
Gene info
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Identity
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Gene
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Long gene namekallikrein related peptidase 3
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Synonyms gene
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Synonyms gene name
- kallikrein 3, (prostate specific antigen)
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Synonyms
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GenBank acession
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Locus
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Discovery year2001-06-22
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- Kallikreins
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VEGA ID