Prekallikrein Heavy Chain (Kininogenin, Fletcher factor, KLKB1, KLK3)
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Catalog numberGEN601722
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Price:
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Size200ug
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Also known asPrekallikrein Heavy Chain
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Other namesPlasma kallikrein; Plasma kallikrein; plasma kallikrein; kininogenin; Fletcher factor; plasma prekallikrein; plasma kallikrein heavy chain; plasma kallikrein light chain; kallikrein B, plasma (Fletcher factor) 1; Fletcher factor; Kininogenin; Plasma prekallikrein
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CategoryAntibodies
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SubcategoryMnoclonal antibodies
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Gene nameKLKB1; KLKB1; PPK; KLK3; KLK3
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Gene name synonimsKLKB1; KLKB1; PPK; KLK3; KLK3
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Other gene namesKLKB1; KLKB1; PPK; KLK3; KLK3
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ClonalityMonoclonal
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Immunoglobulin isotypeIgG1
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Clone1.B.715
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Host organismMouse (Mus musculus)
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Source organismHuman (Homo sapiens)
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Species reactivityHuman (Homo sapiens); Due to limited knowledge and inability for testing each and every species, the reactivity of the antibody may extend to other species which are not listed hereby.
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Specificity and cross reactivityRecognizes two variants (88kD and 85kD) of human prekallikrein and it's activation products human kallikrein (88kD and 85kD), the complexes formed by kallikrein with its endogenous inhibitors C1 inhibitor, alpha-2-macroglobulin and Antithrombin III, and 45kD prekallikrein/kallikrein fragment(s). Does not cross-react with tissue kallikrein. Recognizes prekallikrein and it's activation products in chimpanzee, Rhesus, and baboon plasmas. The epitope, located on the heavy chain, is involved in the interaction between prekallikrein and factor XIIa. ; Since it is not possible to test each and every species our knowledge on the corss reactivity of the antibodies is limited. This particular antibody might cross react with speacies outside of the listed ones.
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Purification methodAffinity Purified by Protein G chromatography.
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Form AppearanceSupplied as a liquid in PBS, pH 7.4. No preservative added.
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ConcentrationN/A
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Storage and shippingStore the antibody at +4 degrees Celsius for short term storage.. Aliquot to avoid repeated freezing and thawing. For optimal long term storage, the antibody should be kept at -20 degrees Celsius. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
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Tested applicationsELISA (EL/EIA), Western Blot (WB)
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DescriptionAplha, transcription related growth factors and stimulating factors or repressing nuclear factors are complex subunits of proteins involved in cell differentiation. Complex subunit associated factors are involved in hybridoma growth, Eosinohils, eritroid proliferation and derived from promotor binding stimulating subunits on the DNA binding complex. NFKB 105 subunit for example is a polypetide gene enhancer of genes in B cells.
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Gene target
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Gene symbolKLKB1, KLK3
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Short namePrekallikrein Heavy Chain (Kininogenin, Fletcher factor, KLKB1, KLK3)
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Alternative nameAnti-Prekallikrein Heavy Chain (Kininogenin, Fletcher factor, KLKB1, KLK3)
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Gene info
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Identity
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Gene
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Long gene namekallikrein B1
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Synonyms gene
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Synonyms gene name
- kallikrein B, plasma (Fletcher factor) 1
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Synonyms name
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GenBank acession
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Locus
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Discovery year1999-04-23
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- Kallikreins
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VEGA ID
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Locus Specific Databases
Gene info
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Identity
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Gene
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Long gene namekallikrein related peptidase 3
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Synonyms gene
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Synonyms gene name
- kallikrein 3, (prostate specific antigen)
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Synonyms
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GenBank acession
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Locus
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Discovery year2001-06-22
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- Kallikreins
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VEGA ID