Prekallikrein Heavy Chain (Kininogenin, Fletcher factor, KLKB1, KLK3)

  • Catalog number
    MBS601722
  • Price
    Please ask
  • Size
    0.1 mg
  • Products_type
    Antibody
  • Products_short_name
    [Prekallikrein Heavy Chain]
  • Products_name_syn
    [Anti -Prekallikrein Heavy Chain (Kininogenin, Fletcher factor, KLKB1, KLK3)]
  • Other_names
    [Plasma kallikrein; Plasma kallikrein; plasma kallikrein; kininogenin; Fletcher factor; plasma prekallikrein; plasma kallikrein heavy chain; plasma kallikrein light chain; kallikrein B, plasma (Fletcher factor) 1; Fletcher factor; Kininogenin; Plasma prekallikrein]
  • Other_gene_names
    [KLKB1; KLKB1; PPK; KLK3; KLK3]
  • Clonality
    Monoclonal
  • Clone
    [1.B.715]
  • Reactivity
    Human
  • Specificity
    Recognizes two variants (88kD and 85kD) of human prekallikrein and it's activation products human kallikrein (88kD and 85kD), the complexes formed by kallikrein with its endogenous inhibitors C1 inhibitor, alpha-2-macroglobulin and Antithrombin III, and 45kD prekallikrein/kallikrein fragment(s). Does not cross-react with tissue kallikrein. Recognizes prekallikrein and it's activation products in chimpanzee, Rhesus, and baboon plasmas. The epitope, located on the heavy chain, is involved in the interaction between prekallikrein and factor XIIa.
  • Purity
    Affinity Purified Purified by Protein G chromatography.
  • Form
    Supplied as a liquid in PBS, pH 7.4. No preservative added.
  • Storage_stability
    May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
  • Tested_application
    ELISA (EL/EIA), Western Blot (WB)
  • Description
    Aplha, transcription related growth factors and stimulating factors or repressing nuclear factors are complex subunits of proteins involved in cell differentiation. Complex subunit associated factors are involved in hybridoma growth, Eosinohils, eritroid proliferation and derived from promotor binding stimulating subunits on the DNA binding complex. NFKB 105 subunit for example is a polypetide gene enhancer of genes in B cells.
  • Gene target
  • Gene symbol
    KLKB1, KLK3
  • Short name
    Prekallikrein Heavy Chain (Kininogenin, Fletcher factor, KLKB1, KLK3)
  • Host
    Mouse
  • Isotype
    IgG1
  • Alternative name
    Prekallikrein Heavy epitope (Kininogenin, Fletcher factor, KLKB1, KLK3)
Gene info
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