- Catalog numberMBS601722
- Product namePrekallikrein Heavy Chain (Kininogenin, Fletcher factor, KLKB1, KLK3)
- Size0.1 mg
- PriceAsk For Price
- Products typeAntibody
- Products short name[Prekallikrein Heavy Chain]
- Products name syn[Anti -Prekallikrein Heavy Chain (Kininogenin, Fletcher factor, KLKB1, KLK3)]
- Other names[Plasma kallikrein; Plasma kallikrein; plasma kallikrein; kininogenin; Fletcher factor; plasma prekallikrein; plasma kallikrein heavy chain; plasma kallikrein light chain; kallikrein B, plasma (Fletcher factor) 1; Fletcher factor; Kininogenin; Plasma prekallikrein]
- Other gene names[KLKB1; KLKB1; PPK; KLK3; KLK3]
- ClonalityMonoclonal
- IsotypeIgG1
- Clone[1.B.715]
- HostMouse
- ReactivityHuman
- SpecificityRecognizes two variants (88kD and 85kD) of human prekallikrein and it's activation products human kallikrein (88kD and 85kD), the complexes formed by kallikrein with its endogenous inhibitors C1 inhibitor, alpha-2-macroglobulin and Antithrombin III, and 45kD prekallikrein/kallikrein fragment(s). Does not cross-react with tissue kallikrein. Recognizes prekallikrein and it's activation products in chimpanzee, Rhesus, and baboon plasmas. The epitope, located on the heavy chain, is involved in the interaction between prekallikrein and factor XIIa.
- PurityAffinity Purified Purified by Protein G chromatography.
- FormSupplied as a liquid in PBS, pH 7.4. No preservative added.
- Storage stabilityMay be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
- Tested applicationELISA (EL/EIA), Western Blot (WB)
- Gene targetPrekallikrein Heavy Chain Kininogenin Fletcher factor KLKB1 KLK3
- Identity:HGNC:6371
- Gene:KLKB1
- Long gene name:kallikrein B1
- Synonyms gene name:kallikrein B, plasma (Fletcher factor) 1
- Discovery year:1999-04-23
- Entrez gene record:3818
- Pubmed identification:9535413, 3521732
- RefSeq identity:NM_000892
- Classification:Kallikreins
- VEGA ID:OTTHUMG00000150347
- Identity:HGNC:6364
- Gene:KLK3
- Long gene name:kallikrein related peptidase 3
- Synonyms gene name:kallikrein 3, (prostate specific antigen)
- Synonyms:PSA
- Discovery year:2001-06-22
- Entrez gene record:354
- Pubmed identification:2456523, 2436946, 16800724, 16800723
- RefSeq identity:NM_145864
- Classification:Kallikreins
- VEGA ID:OTTHUMG00000182867
- Gene symbolKLKB1, KLK3
- isotype filter
- IgG1
- Short namePrekallikrein Heavy Chain (Kininogenin, Fletcher factor, KLKB1, KLK3)
Gene info
Locus Specific Databases:LRG_565