P5CS (016) Mouse mAb

• Catalog number
  MBS435179
• Price
  Please ask
• Size
  0.02 mL

• Products_type
  Antibody
• Products_short_name
  [P5CS]
• Products_name_syn
  [aldehyde dehydrogenase 18 family, member A1; aldehyde dehydrogenase 18A1; Aldehyde dehydrogenase family 18 member A1; ALDH18A1; Delta-1-pyrroline-5-carboxylate synthase; delta-1-pyrroline-5-carboxylate synthetase; delta1-pyrroline-5-carboxlate synthetase; glutamate gamma-semialdehyde synthetase; GSAS; MGC117316; P5CS; PYCS; pyrroline-5-carboxylate synthetase (glutamate gamma-semialdehyde synthetase); 2810433K04Rik; ADCL3; AI429789; ALDH18A1; ARCL3A; GSAS; P5CS; PYCS; SPG9A; SPG9B]
• Other_names
  [delta-1-pyrroline-5-carboxylate synthase isoform 2; Delta-1-pyrroline-5-carboxylate synthase; delta-1-pyrroline-5-carboxylate synthase; aldehyde dehydrogenase 18 family member A1; Aldehyde dehydrogenase family 18 member A1Including the following 2 domains:Glutamate 5-kinase (EC:2.7.2.111 PublicationManual assertion based on experiment iniRef.14"ALDH18A1 gene mutations cause dominant spastic paraplegia SPG9: loss of function effect and plausibility of a dominant negative mechanism."Panza E., Escamilla-Honrubia J.M., Marco-Marin C., Gougeard N., De Michele G., Morra V.B., Liguori R., Salviati L., Donati M.A., Cusano R., Pippucci T., Ravazzolo R., Nemeth A.H., Smithson S., Davies S., Hurst J.A., Bordo D., Rubio V., Seri M.Brain 139:E3-E3(2016) [PubMed] [Europe PMC] [Abstract]Cited for: FUNCTION, CATALYTIC ACTIVITY, PATHWAY, SUBUNIT, SUBCELLULAR LOCATION, INVOLVEMENT IN SPG9A, VARIANTS SPG9A LEU-243 AND GLN-252, CHARACTERIZATION OF VARIANTS SPG9A LEU-243 AND GLN-252.]
• Products_gene_name
  [P5CS]
• Other_gene_names
  [ALDH18A1; ALDH18A1; GSAS; P5CS; PYCS; SPG9; ADCL3; SPG9A; SPG9B; ARCL3A; GSAS; P5CS; PYCS; P5CS; GK; GPR]
• Clonality
  Monoclonal
• Reactivity
  Human
• Storage_stability
  Store at -20 degree C. Stable for one year from the date of shipment.
• Tested_application
  Western Blot (WB), Immunoprecipitation (IP), Flow Cytometry (FC/FACS)
• Test
  Mouse or mice from the Mus musculus species are used for production of mouse monoclonal antibodies or mabs and as research model for humans in your lab. Mouse are mature after 40 days for females and 55 days for males. The female mice are pregnant only 20 days and can give birth to 10 litters of 6-8 mice a year. Transgenic, knock-out, congenic and inbread strains are known for C57BL/6, A/J, BALB/c, SCID while the CD-1 is outbred as strain.
• Latin name
  Mus musculus

• Gene target
  P5CS   016   mAb  
• Gene symbol
  ALDH18A1
• Short name
  P5CS (016) Mouse mAb
• Technique
  Mouse, mouses
• Host
  Mouse
• Isotype
  IgG
• Species
  Mouse, Mouses
• Alternative name
  P5CS (016) Mouse monoclonal
• Alternative technique
  murine

Gene info

• Identity
  HGNC:9722
• Gene
  ALDH18A1
• Long gene name
  aldehyde dehydrogenase 18 family member A1
• Synonyms gene
  • GSAS
  • PYCS
  • SPG9
• Synonyms gene name
  • pyrroline-5-carboxylate synthetase (glutamate gamma-semialdehyde synthetase)
  • spastic paraplegia 9 (autosomal dominant)
• Synonyms
  • P5CS
• Synonyms name
  • delta-1-pyrroline-5-carboxylate synthase
• GenBank acession
  • X94453
• Locus
  10q24.1
• Discovery year
  1996-10-02
• Entrez gene record
  5832
• Pubmed identfication
  • 8921385
  • 26297558
• RefSeq identity
  • NM_002860
• Classification
  • Aldehyde dehydrogenases
• VEGA ID
  OTTHUMG00000018815

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