P5CS (012) Mouse mAb
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Catalog numberMBS435154
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PricePlease ask
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Size0.05 mL
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Products_typeAntibody
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Products_short_name[P5CS]
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Products_name_syn[P5CS(012) Mouse mAb; aldehyde dehydrogenase 18 family, member A1; aldehyde dehydrogenase 18A1; Aldehyde dehydrogenase family 18 member A1; ALDH18A1; Delta-1-pyrroline-5-carboxylate synthase; delta-1-pyrroline-5-carboxylate synthetase; delta1-pyrroline-5-carboxlate synthetase; glutamate gamma-semialdehyde synthetase; GSAS; MGC117316; P5CS; PYCS; pyrroline-5-carboxylate synthetase (glutamate gamma-semialdehyde synthetase); 2810433K04Rik; ADCL3; AI429789; ALDH18A1; ARCL3A; GSAS; P5CS; PYCS; SPG9A; SPG9B]
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Other_names[delta-1-pyrroline-5-carboxylate synthase isoform 2; Delta-1-pyrroline-5-carboxylate synthase; delta-1-pyrroline-5-carboxylate synthase; aldehyde dehydrogenase 18 family member A1; Aldehyde dehydrogenase family 18 member A1Including the following 2 domains:Glutamate 5-kinase (EC:2.7.2.111 PublicationManual assertion based on experiment iniRef.14"ALDH18A1 gene mutations cause dominant spastic paraplegia SPG9: loss of function effect and plausibility of a dominant negative mechanism."Panza E., Escamilla-Honrubia J.M., Marco-Marin C., Gougeard N., De Michele G., Morra V.B., Liguori R., Salviati L., Donati M.A., Cusano R., Pippucci T., Ravazzolo R., Nemeth A.H., Smithson S., Davies S., Hurst J.A., Bordo D., Rubio V., Seri M.Brain 139:E3-E3(2016) [PubMed] [Europe PMC] [Abstract]Cited for: FUNCTION, CATALYTIC ACTIVITY, PATHWAY, SUBUNIT, SUBCELLULAR LOCATION, INVOLVEMENT IN SPG9A, VARIANTS SPG9A LEU-243 AND GLN-252, CHARACTERIZATION OF VARIANTS SPG9A LEU-243 AND GLN-252.]
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Products_gene_name[P5CS]
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Other_gene_names[ALDH18A1; ALDH18A1; GSAS; P5CS; PYCS; SPG9; ADCL3; SPG9A; SPG9B; ARCL3A; GSAS; P5CS; PYCS; P5CS; GK; GPR]
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ClonalityMonoclonal
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ReactivityHuman
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Storage_stabilityStore at -20 degree C. Stable for one year from the date of shipment.
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Tested_applicationWestern Blot (WB), Immunoprecipitation (IP), Flow Cytometry (FC/FACS)
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TestMouse or mice from the Mus musculus species are used for production of mouse monoclonal antibodies or mabs and as research model for humans in your lab. Mouse are mature after 40 days for females and 55 days for males. The female mice are pregnant only 20 days and can give birth to 10 litters of 6-8 mice a year. Transgenic, knock-out, congenic and inbread strains are known for C57BL/6, A/J, BALB/c, SCID while the CD-1 is outbred as strain.
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Latin nameMus musculus
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Gene target
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Gene symbolALDH18A1
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Short nameP5CS (012) Mouse mAb
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TechniqueMouse, mouses
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HostMouse
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IsotypeIgG
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SpeciesMouse, Mouses
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Alternative nameP5CS (012) Mouse monoclonal
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Alternative techniquemurine
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Gene info
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Identity
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Gene
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Long gene namealdehyde dehydrogenase 18 family member A1
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Synonyms gene
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Synonyms gene name
- pyrroline-5-carboxylate synthetase (glutamate gamma-semialdehyde synthetase)
- spastic paraplegia 9 (autosomal dominant)
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Synonyms
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Synonyms name
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GenBank acession
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Locus
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Discovery year1996-10-02
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- Aldehyde dehydrogenases
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VEGA ID