-
Products_type
Antibody
-
Products_short_name
[Nerve Growth Factor Receptor, p75NTR]
-
Products_name_syn
[Anti -Nerve Growth Factor Receptor, p75NTR (Low-affinity, NGF receptor, Neurotrophin receptor, Gp80-LNGFR, p75 ICD)]
-
Other_names
[nerve growth factor receptor; nerve growth factor receptor; NRH; nerve growth factor receptor (TNFR superfamily, member 16); nerve growth factor receptor
-
Other_gene_names
[ngfr; nrh1; CD271; NRH1b; p75ntr; p75(NTR); tnfrsf16; MGC131034; Gp80-LNGFR]
-
Clonality
Monoclonal
-
Clone
[9G396]
-
Reactivity
Rat
-
Specificity
Recognizes the extracellular domain of the neurotrophin receptor in p75NTR-expressing cells in rat spinal cord and brain. Does not cross react with p75NTR-expressing cells in other species.
-
Purity
Affinity Purified Purified by Protein G affinity chromatography.
-
Form
Supplied as a lyophilized powder, 1% BSA. Reconstitute with 100ul sterile ddH2O.
-
Storage_stability
Lyophilized powder may be stored at -20 degree C. Stable for 12 months at -20 degree C. Reconstitute with sterile ddH2O. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Reconstituted product is stable for 12 months at -20 degree C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
-
Tested_application
ELISA (EL/EIA), Western Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)
-
Test
A high affinity purification column was use to purify Nerve Growth Factor Receptor, p75NTR ( - , NGF receptor, Neurotrophin receptor, Gp80-LNGFR, p75 ICD) by MyBioSource by chromatographic size exclusion.
-
Description
Aplha, transcription related growth factors and stimulating factors or repressing nuclear factors are complex subunits of proteins involved in cell differentiation. Complex subunit associated factors are involved in hybridoma growth, Eosinohils, eritroid proliferation and derived from promotor binding stimulating subunits on the DNA binding complex. NFKB 105 subunit for example is a polypetide gene enhancer of genes in B cells. The receptors are ligand binding factors of type 1, 2 or 3 and protein-molecules that receive chemical-signals from outside a cell. When such chemical-signals couple or bind to a receptor, they cause some form of cellular/tissue-response, e.g. a change in the electrical-activity of a cell. In this sense, am olfactory receptor is a protein-molecule that recognizes and responds to endogenous-chemical signals, chemokinesor cytokines e.g. an acetylcholine-receptor recognizes and responds to its endogenous-ligand, acetylcholine. However, sometimes in pharmacology, the term is also used to include other proteins that are drug-targets, such as enzymes, transporters and ion-channels.
-
Gene target
-
Gene symbol
NGF, NGF-AS1
-
Short name
Nerve Growth Factor Receptor, p75NTR ( - , NGF receptor, Neurotrophin receptor, Gp80-LNGFR, p75 ICD)
-
Technique
affinity
-
Host
Mouse
-
Isotype
IgG
-
Alternative name
Nerve Growth Factor Receptor, p75NTR (Low-protein, nerve growth factor (beta polypeptide) receptor, Neurotrophin receptor, Gp80-LNGFR, p75 ICD)
-
Alternative to gene target
nerve growth factor (beta polypeptide), Beta-NGF and HSAN5 and NGFB, NGF and IDBG-101347 and ENSG00000134259 and 4803, growth factor activity, Extracellular, Ngf and IDBG-180362 and ENSMUSG00000027859 and 18049, NGF and IDBG-648895 and ENSBTAG00000007446 and 281350
-
Tissue
nerve
-
