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Products_type
Antibody
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Products_short_name
[Nerve Growth Factor Receptor, p75NTR]
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Products_name_syn
[Anti -Nerve Growth Factor Receptor, p75NTR (Low-affinity NGF receptor, Gp80-LNGFR, p75 ICD, Low affinity neurotrophin receptor p75NTR)]
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Other_names
[nerve growth factor receptor; nerve growth factor receptor; NRH; nerve growth factor receptor (TNFR superfamily, member 16); nerve growth factor receptor]
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Other_gene_names
[ngfr; nrh1; CD271; NRH1b; p75ntr; p75(NTR); tnfrsf16; MGC131034; Gp80-LNGFR]
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Clonality
Monoclonal
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Clone
[9G398]
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Reactivity
Rat
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Specificity
Recognizes the extracellular domain of the neurotrophin receptor p75NTR in rat. MC192 antibody may be used for immunocytochemical localisation of rat cells expressing p75NTR, ELISA and western blot. Does not react with mouse.
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Purity
Affinity Purified Purified by affinity chromatography.
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Form
Supplied as a liquid in PBS, pH 7.2. No preservative added.
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Storage_stability
May be stored at 4 degree C. For long-term storage, aliquot and store at 4 degree C. Do not freeze. Aliquots are stable for up to 4 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer. Note: We do not recommended adding glycerol as a cryopreservative.
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Tested_application
ELISA (EL/EIA), Immunohistochemistry (IHC), Immunocytochemistry (ICC), Flow Cytometry (FC/FACS)
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Test
A high affinity purification column was use to purify Nerve Growth Factor Receptor, p75NTR ( - NGF receptor, Gp80-LNGFR, p75 ICD, neurotrophin receptor p75NTR) by MyBioSource by chromatographic size exclusion.
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Description
Aplha, transcription related growth factors and stimulating factors or repressing nuclear factors are complex subunits of proteins involved in cell differentiation. Complex subunit associated factors are involved in hybridoma growth, Eosinohils, eritroid proliferation and derived from promotor binding stimulating subunits on the DNA binding complex. NFKB 105 subunit for example is a polypetide gene enhancer of genes in B cells. The receptors are ligand binding factors of type 1, 2 or 3 and protein-molecules that receive chemical-signals from outside a cell. When such chemical-signals couple or bind to a receptor, they cause some form of cellular/tissue-response, e.g. a change in the electrical-activity of a cell. In this sense, am olfactory receptor is a protein-molecule that recognizes and responds to endogenous-chemical signals, chemokinesor cytokines e.g. an acetylcholine-receptor recognizes and responds to its endogenous-ligand, acetylcholine. However, sometimes in pharmacology, the term is also used to include other proteins that are drug-targets, such as enzymes, transporters and ion-channels.
