Mouse anti Rb1 [1F8]: Fluorescein

• Catalog number
  MBS375371
• Price
  Please ask
• Size
  0.05 mL

• Products_type
  Antibody
• Products_short_name
  [Rb1]
• Products_name_syn
  [OSRC; p105-Rb; pp110; pRb; Rb; RB1; retinoblastoma 1; retinoblastoma suspectibility protein; Retinoblastoma-associated protein]
• Products_gene_name
  [Rb1]
• Clonality
  Monoclonal
• Clone
  [1F8]
• Reactivity
  Mouse, Human
• Specificity
  This antibody recognises retinoblastoma-associated protein (RB), a 105kDa tumour suppressor which is also known as Rb1. Rb1 functions as a transcription factor that controls cell cycle progression (at the G1/S phase transition) through its repression of E2F-mediated transcription. Mutation of the Rb gene is found frequently in human sarcomas, lung, bladder and breast carcinomas and is the molecular basis for hereditary disposition to retinoblastoma.
• Purity
  Purified on protein A from tissue culture supernatant.
• Form
  Purified IgG conjugated to Fluorescein, supplied in Phosphate buffered saline (PBS) containing 0.09% Sodium azide
• Concentration
  1mg/ml
• Tested_application
  Immunocytochemistry (ICC), Immunofluorescence (IF), Immunohistochemistry (IHC) Formalin
• Description
  This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided.
• Test
  Mouse or mice from the Mus musculus species are used for production of mouse monoclonal antibodies or mabs and as research model for humans in your lab. Mouse are mature after 40 days for females and 55 days for males. The female mice are pregnant only 20 days and can give birth to 10 litters of 6-8 mice a year. Transgenic, knock-out, congenic and inbread strains are known for C57BL/6, A/J, BALB/c, SCID while the CD-1 is outbred as strain.
• Latin name
  Mus musculus

• Gene target
  Rb1   [1F8]   Fluorescein  
• Gene symbol
  IL36B
• Short name
  Mouse anti Rb1 [1F8]: Fluorescein
• Technique
  Mouse, anti, antibody to, mouses
• Host
  Mouse
• Isotype
  IgG1
• Species
  Mouse, Mouses
• Alternative name
  Mouse antibody to retinoblastoma 1 [1F8]: Fluorescein
• Alternative technique
  murine, antibodies
• Alternative to gene target
  retinoblastoma 1, OSRC and p105-Rb and pp110 and PPP1R130 and pRb and RB, RB1 and IDBG-32092 and ENSG00000139687 and 5925, phosphoprotein binding, nuclei, Rb1 and IDBG-179829 and ENSMUSG00000022105 and 19645, BT.68871 and IDBG-629082 and ENSBTAG00000006640 and 534712

Gene info

• Identity
  HGNC:15564
• Gene
  IL36B
• Long gene name
  interleukin 36 beta
• Synonyms gene
  • IL1F8
• Synonyms gene name
  • interleukin 1 family, member 8 (eta)
• Synonyms
  • FIL1
  • IL-1H2
  • IL-1F8
  • FILI-(ETA)
  • IL1-ETA
  • IL1H2
  • MGC126880
  • MGC126882
• GenBank acession
  • AF201833
• Locus
  2q14.1
• Discovery year
  2002-08-02
• Entrez gene record
  27177
• Pubmed identfication
  • 10625660
  • 10512743
  • 16646978
• RefSeq identity
  • NM_014438
• Classification
  • Interleukins
• VEGA ID
  OTTHUMG00000131338

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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