Mouse anti Rb1 [1F8]: Horseradish peroxidase (HRP)
-
Catalog number
MBS375256
-
Price
648.41 USD
-
Size
0.05 mL
-
-
Products_type
Antibody
-
Products_short_name
[Rb1]
-
Products_name_syn
[OSRC; p105-Rb; pp110; pRb; Rb; RB1; retinoblastoma 1; retinoblastoma suspectibility protein; Retinoblastoma-associated protein]
-
Products_gene_name
[Rb1]
-
Clonality
Monoclonal
-
Clone
[1F8]
-
Reactivity
Mouse, Human
-
Specificity
This antibody recognises retinoblastoma-associated protein (RB), a 105kDa tumour suppressor which is also known as Rb1. Rb1 functions as a transcription factor that controls cell cycle progression (at the G1/S phase transition) through its repression of E2F-mediated transcription. Mutation of the Rb gene is found frequently in human sarcomas, lung, bladder and breast carcinomas and is the molecular basis for hereditary disposition to retinoblastoma.
-
Purity
Purified on protein A from tissue culture supernatant.
-
Form
Purified IgG conjugated to Horseradish Peroxidase, supplied in Phosphate buffered saline (PBS) containing 0.01% Thiomersal
-
Concentration
1mg/ml
-
Tested_application
Immunohistochemistry (IHC) Formalin, Immunoprecipitation (IP), Western Blot (WB)
-
Description
This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided.
-
Properties
HRP conjugates are often primary rabbit polyclonal antibodies couples to the enzyme horseradish peroxidase (HRP), found in the roots of horseradish. Also monoclonal HRP conjugates are often used for Western Blot.
-
Conjugation
HRP Conjugated
-
Test
Mouse or mice from the Mus musculus species are used for production of mouse monoclonal antibodies or mabs and as research model for humans in your lab. Mouse are mature after 40 days for females and 55 days for males. The female mice are pregnant only 20 days and can give birth to 10 litters of 6-8 mice a year. Transgenic, knock-out, congenic and inbread strains are known for C57BL/6, A/J, BALB/c, SCID while the CD-1 is outbred as strain.
-
Latin name
Mus musculus
-
Conjugate
Peroxidases with EC number 1.11.1.x are catalyzing the reaction of
ROOR' + electron donor (2 e−) + 2H+ → ROH + R'OH
-
Gene target
-
Gene symbol
IL36B
-
Short name
Mouse anti Rb1 [1F8]: Horseradish ( )
-
Technique
Mouse, anti, antibody to, mouses
-
Host
Mouse
-
Isotype
IgG1
-
Label
horseradish
-
Species
Mouse, Mouses
-
Alternative name
Mouse antibody to retinoblastoma 1 [1F8]: Horseradish peroxidase (horseradish peroxidase)
-
Alternative technique
murine, antibodies
-
Alternative to gene target
retinoblastoma 1, OSRC and p105-Rb and pp110 and PPP1R130 and pRb and RB, RB1 and IDBG-32092 and ENSG00000139687 and 5925, phosphoprotein binding, nuclei, Rb1 and IDBG-179829 and ENSMUSG00000022105 and 19645, BT.68871 and IDBG-629082 and ENSBTAG00000006640 and 534712
-
Gene info
-
Identity
-
Gene
-
Long gene name
interleukin 36 beta
-
Synonyms gene
-
Synonyms gene name
- interleukin 1 family, member 8 (eta)
-
Synonyms
-
GenBank acession
-
Locus
-
Discovery year
2002-08-02
-
Entrez gene record
-
Pubmed identfication
-
RefSeq identity
-
Classification
-
VEGA ID
MeSH Data
-
Name
-
Concept
Scope note:
Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
-
Tree numbers
- E05.196.401.143
- E05.301.300.096
- E05.478.566.320.200
- E05.601.262
- E05.601.470.320.200
-
Qualifiers
ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data
Product images
Similar products