MOUSE ANTI AMPK ALPHA 1/2
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Catalog number
MBS219501
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Price
Please ask
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Size
0.1 mg
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Products_type
Antibody
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Products_short_name
[AMPK ALPHA 1/2]
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Other_names
[5'-AMP-activated protein kinase catalytic subunit alpha-1 isoform 1; 5'-AMP-activated protein kinase catalytic subunit alpha-1; 5'-AMP-activated protein kinase catalytic subunit alpha-1; 5'-AMP-activated protein kinase, catalytic alpha-1 chain; ACACA kinase; AMP -activate kinase alpha 1 subunit; AMP-activated protein kinase, catalytic, alpha-1; AMPK alpha 1; AMPK subunit alpha-1; HMGCR kinase; acetyl-CoA carboxylase kinase; hydroxymethylglutaryl-CoA reductase kinase; tau-protein kinase PRKAA1; protein kinase, AMP-activated, alpha 1 catalytic subunit; Acetyl-CoA carboxylase kinase (EC:2.7.11.27); ACACA kinase; Hydroxymethylglutaryl-CoA reductase kinase (EC:2.7.11.31); HMGCR kinase; Tau-protein kinase PRKAA1 (EC:2.7.11.26)]
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Other_gene_names
[PRKAA1; PRKAA1; AMPK; AMPKa1; AMPK1; AMPK subunit alpha-1; ACACA kinase; HMGCR kinase]
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Clonality
Monoclonal
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Clone
[84.1]
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Specificity
This item recognises both the alpha 1 and the alpha 2 isoforms of AMP-activated protein kinase (AMPK). AMPK is a highly conserved heterotrimeric protein kinase found in all eukaryotes. The heterotrimeric complex exists as multiple isoforms and consists of a catalytic alpha subunit, which is stabilised by non-catalytic regulatory beta- and gamma- subunits. AMPK plays a vital role in maintaining cellular energy homeostasis and is activated by rising levels of AMP under conditions of hypoxia, ischemia, exercise, low glucose levels. AMPK may play an important role in the control of type 2 diabetes and metabolic syndromes. Recent studies suggest that AMPK functions as a suppressor of cell proliferation of both malignant and normal cells.
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Form
Purified Purified IgG - liquid
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Concentration
IgG concentration 1.0mg/ml
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Storage_stability
Store at 4 degree C or at -20 degree C if preferred. Storage in frost-free freezers is not recommended. This product should be stored undiluted. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use. Shelf Life: 18 months from date of despatch.
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Tested_application
Immunohistology Frozen, ELISA (EIA), Immunofluorescence (IF), Immunoprecipitation (IP), Western Blot (WB)
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Description
The MOUSE ANTI AMPK ALPHA 1/2 is a α- or alpha protein sometimes glycoprotein present in blood. This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided.
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Test
Mouse or mice from the Mus musculus species are used for production of mouse monoclonal antibodies or mabs and as research model for humans in your lab. Mouse are mature after 40 days for females and 55 days for males. The female mice are pregnant only 20 days and can give birth to 10 litters of 6-8 mice a year. Transgenic, knock-out, congenic and inbread strains are known for C57BL/6, A/J, BALB/c, SCID while the CD-1 is outbred as strain.
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Latin name
Mus musculus
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Gene target
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Gene symbol
PRKAA2, SRPRA, CBX5, AGPAT1, DRAP1, SCART1, TUBA3D, TLK2, CAMK1, CTNNAL1
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Short name
MOUSE ANTI AMPK ALPHA 1/2
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Technique
Mouse, anti, antibody to, mouses
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Host
Mouse
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Isotype
IgG2a
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Species
Mouse, Mouses
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Alternative name
MOUSE antibody to AMPK a 1/2
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Alternative technique
murine, antibodies
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Gene info
Gene info
Gene info
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Identity
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Gene
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Long gene name
chromobox 5
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Synonyms gene name
- chromobox homolog 5 (Drosophila HP1 alpha)
- chromobox homolog 5 (HP1 alpha homolog, Drosophila)
- chromobox homolog 5
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Synonyms
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Synonyms name
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GenBank acession
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Locus
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Discovery year
1999-10-12
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- Chromobox family
- MicroRNA protein coding host genes
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VEGA ID
Gene info
Gene info
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Identity
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Gene
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Long gene name
DR1 associated protein 1
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Synonyms
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Synonyms name
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GenBank acession
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Locus
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Discovery year
1998-09-22
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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VEGA ID
Gene info
Gene info
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Identity
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Gene
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Long gene name
tubulin alpha 3d
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Synonyms
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Synonyms name
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GenBank acession
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Locus
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Discovery year
2007-02-12
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
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VEGA ID
Gene info
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Identity
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Gene
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Long gene name
tousled like kinase 2
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Synonyms gene name
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Synonyms
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GenBank acession
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Locus
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Discovery year
2000-01-07
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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VEGA ID
Gene info
Gene info
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Identity
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Gene
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Long gene name
catenin alpha like 1
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Synonyms gene name
- catenin (cadherin-associated protein), alpha-like 1
- catenin alpha-like 1
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Synonyms
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Synonyms name
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GenBank acession
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Locus
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Discovery year
1998-12-09
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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VEGA ID
MeSH Data
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Name
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Concept
Scope note:
Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
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Tree numbers
- E05.196.401.143
- E05.301.300.096
- E05.478.566.320.200
- E05.601.262
- E05.601.470.320.200
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Qualifiers
ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data
Product images
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