GOAT ANTI HUMAN AMPK ALPHA 2

• Catalog number
  MBS224265
• Price
  Please ask
• Size
  5x0.1 mg

• Products_type
  Antibody
• Products_short_name
  [AMPK ALPHA 2]
• Other_names
  [5'-AMP-activated protein kinase catalytic subunit alpha-2; 5'-AMP-activated protein kinase catalytic subunit alpha-2; 5'-AMP-activated protein kinase catalytic subunit alpha-2; 5'-AMP-activated protein kinase, catalytic alpha-2 chain; ACACA kinase; AMP-activated protein kinase alpha-2 subunit variant 2; AMP-activated protein kinase alpha-2 subunit variant 3; AMPK alpha 2; AMPK subunit alpha-2; AMPK-alpha-2 chain; HMGCR kinase; acetyl-CoA carboxylase kinase; hydroxymethylglutaryl-CoA reductase kinase; protein kinase, AMP-activated, alpha 2 catalytic subunit; Acetyl-CoA carboxylase kinase (EC:2.7.11.27); ACACA kinase; Hydroxymethylglutaryl-CoA reductase kinase (EC:2.7.11.31); HMGCR kinase]
• Other_gene_names
  [PRKAA2; PRKAA2; AMPK; AMPK2; PRKAA; AMPKa2; AMPK; AMPK2; AMPK subunit alpha-2; ACACA kinase; HMGCR kinase]
• Clonality
  Polyclonal
• Reactivity
  Bovine (Expected from Sequence), Dog (Expected from Sequence), Mouse, Pig (Expected from Sequence), Rat
• Specificity
  This item specifically recognises AMPK alpha 2, otherwise known as PRKAA2, a Serine/threonine-protein kinase and the catalytic subunit of the AMP-activated protein kinase (AMPK), a central metabolic sensor, essential for the regulation of fatty acid and cholesterol synthesis, in response to fluctuations in nutrient and intracellular energy levels. AMPK has been implicated as a suppressor of cell proliferation of both normal and malignant cells, and recent studies have shown that the binding of AMPK to the PS domain of ULK1, is essential for ULK1-mediated autophagy, and that the phosphorylation of raptor by AMPK, plays an important role in autophagy induction.
• Form
  Purified Purified IgG - liquid
• Concentration
  IgG concentration 0.5mg/ml
• Storage_stability
  Store at 4 degree C or at -20 degree C if preferred. Storage in frost-free freezers is not recommended. This product should be stored undiluted. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use. Shelf Life: 18 months from date of despatch.
• Tested_application
  ELISA (EIA), Western Blot (WB)
• Description
  The GOAT ANTI AMPK ALPHA 2 is a α- or alpha protein sometimes glycoprotein present in blood. This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided. Antibody against the Hu protein or peptide or recombinant supplied in 1 volumes. Ask for quote if you need bulk.
• Latin name
  Capra aegagrus hircus
• Properties
  Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.

• Gene target
  AMPK   ALPHA  
• Gene symbol
  PRKAA2, SRPRA, CBX5, AGPAT1, DRAP1, SCART1, TUBA3D, TLK2, CAMK1, CTNNAL1
• Short name
  GOAT ANTI AMPK ALPHA 2
• Technique
  anti human, anti, Goat, antibody to, anti human antibodies, goats
• Host
  Goat, The goat polyclonal antibodies are directed against human genes or rabbit or mouse IgGs (H +L) chain primary antibodies and conjugated for detection. It are very good secondary antibodies that are affinity purified and have a good affinity themselves too. Often KLH is coupled to the antigen so anti KLH can be present in the vial.
• Isotype
  IgG
• Species
  Human, Goats, Humans
• Alternative name
  caprine antibody to H. sapiens AMPK a 2
• Alternative technique
  antibodies, caprine

Gene info

• Identity
  HGNC:9377
• Gene
  PRKAA2
• Long gene name
  protein kinase AMP-activated catalytic subunit alpha 2
• Synonyms gene
  • PRKAA
• Synonyms gene name
  • protein kinase, AMP-activated, alpha 2 catalytic subunit
• Synonyms
  • AMPK
  • AMPKa2
• GenBank acession
  • BC069823
• Locus
  1p32.2
• Discovery year
  1995-12-12
• Entrez gene record
  5563
• Pubmed identfication
  • 7959015
• RefSeq identity
  • NM_006252
• VEGA ID
  OTTHUMG00000008282

Gene info

• Identity
  HGNC:11307
• Gene
  SRPRA
• Long gene name
  SRP receptor subunit alpha
• Synonyms gene
  • SRPR
• Synonyms gene name
  • signal recognition particle receptor (docking protein)
• Synonyms
  • SRP-alpha
  • Sralpha
  • SR-alpha
• GenBank acession
  • BC001162
• Locus
  11q24.2
• Discovery year
  2001-06-22
• Entrez gene record
  6734
• Pubmed identfication
  • 3340536
  • 1312991
• RefSeq identity
  • NM_003139
• VEGA ID
  OTTHUMG00000165826

Gene info

• Identity
  HGNC:1555
• Gene
  CBX5
• Long gene name
  chromobox 5
• Synonyms gene name
  • chromobox homolog 5 (Drosophila HP1 alpha)
  • chromobox homolog 5 (HP1 alpha homolog, Drosophila)
  • chromobox homolog 5
• Synonyms
  • HP1Hs-alpha
  • HP1
  • HP1-ALPHA
• Synonyms name
  • HP1 alpha homolog (Drosophila)
• GenBank acession
  • U26311
• Locus
  12q13.13
• Discovery year
  1999-10-12
• Entrez gene record
  23468
• Pubmed identfication
  • 8663349
• RefSeq identity
  • NM_012117
• Classification
  • Chromobox family
  • MicroRNA protein coding host genes
• VEGA ID
  OTTHUMG00000169700

Gene info

• Identity
  HGNC:324
• Gene
  AGPAT1
• Long gene name
  1-acylglycerol-3-phosphate O-acyltransferase 1
• Synonyms gene name
  • 1-acylglycerol-3-phosphate O-acyltransferase 1 (lysophosphatidic acid acyltransferase, alpha)
• Synonyms
  • LPAAT-alpha
• Synonyms name
  • lysophosphatidic acid acyltransferase, alpha
• GenBank acession
  • U56417
• Locus
  6p21.32
• Discovery year
  1999-12-07
• Entrez gene record
  10554
• Pubmed identfication
  • 9461603
  • 9291118
• RefSeq identity
  • NM_006411
• Classification
  • MicroRNA protein coding host genes
  • 1-acylglycerol-3-phosphate O-acyltransferases
• VEGA ID
  OTTHUMG00000031210

Gene info

• Identity
  HGNC:3019
• Gene
  DRAP1
• Long gene name
  DR1 associated protein 1
• Synonyms
  • NC2-alpha
• Synonyms name
  • negative cofactor 2 alpha
  • DR1-associated corepressor
• GenBank acession
  • U41843
• Locus
  11q13.1
• Discovery year
  1998-09-22
• Entrez gene record
  10589
• Pubmed identfication
  • 8608938
• RefSeq identity
  • NM_006442
• VEGA ID
  OTTHUMG00000166723

Gene info

• Identity
  HGNC:32411
• Gene
  SCART1
• Long gene name
  scavenger receptor family member expressed on T cells 1
• Synonyms gene name
  • scavenger receptor family member expressed on T-cells 1
• Synonyms
  • CD163c-alpha
• Locus
  10q26.3
• Discovery year
  2017-02-28
• Entrez gene record
  619207
• Pubmed identfication
  • 19297026
  • 22795646
• RefSeq identity
  • NM_001396050
• Classification
  • Scavenger receptor cysteine rich domain containing

Gene info

• Identity
  HGNC:24071
• Gene
  TUBA3D
• Long gene name
  tubulin alpha 3d
• Synonyms
  • H2-ALPHA
• Synonyms name
  • alpha-tubulin isotype H2-alpha
• GenBank acession
  • K03460
• Locus
  2q21.1
• Discovery year
  2007-02-12
• Entrez gene record
  113457
• Pubmed identfication
  • 3785200
• RefSeq identity
  • NM_080386
• Classification
  • Tubulins
• VEGA ID
  OTTHUMG00000153600

Gene info

• Identity
  HGNC:11842
• Gene
  TLK2
• Long gene name
  tousled like kinase 2
• Synonyms gene name
  • tousled-like kinase 2
• Synonyms
  • PKU-ALPHA
  • MGC44450
• GenBank acession
  • AB004884
• Locus
  17q23.2
• Discovery year
  2000-01-07
• Entrez gene record
  11011
• Pubmed identfication
  • 9427565
  • 10523312
• RefSeq identity
  • NM_006852
• VEGA ID
  OTTHUMG00000179176

Gene info

• Identity
  HGNC:1459
• Gene
  CAMK1
• Long gene name
  calcium/calmodulin dependent protein kinase I
• Synonyms
  • CaMKI
  • CaMKI-alpha
• GenBank acession
  • L41816
• Locus
  3p25.3
• Discovery year
  1998-10-16
• Entrez gene record
  8536
• Pubmed identfication
  • 7641687
• RefSeq identity
  • NM_003656
• Classification
  • Calmodulin dependent protein kinases
• VEGA ID
  OTTHUMG00000128419

Gene info

• Identity
  HGNC:2512
• Gene
  CTNNAL1
• Long gene name
  catenin alpha like 1
• Synonyms gene name
  • catenin (cadherin-associated protein), alpha-like 1
  • catenin alpha-like 1
• Synonyms
  • CLLP
  • alpha-CATU
• Synonyms name
  • alpha-catulin
  • alpha2-catulin
• GenBank acession
  • AF030233
• Locus
  9q31.3
• Discovery year
  1998-12-09
• Entrez gene record
  8727
• Pubmed identfication
  • 9806841
• RefSeq identity
  • NM_003798
• VEGA ID
  OTTHUMG00000020466

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

Product images

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