Interleukin-2 Soluble Receptor alpha (IL-2 sRa)

Catalog number

MBS590008
Price

Please ask
Size

192 Wells

Products_type

ELISA Kit
Products_short_name

[Interleukin-2]
Other_names

[interleukin-2 receptor subunit alpha; Interleukin-2 receptor subunit alpha; interleukin-2 receptor subunit alpha; IL-2 receptor subunit alpha; IL-2R subunit alpha; TAC antigen; interleukin 2 receptor, alpha; TAC antigen; p55; CD_antigen: CD25]
Products_gene_name

[IL-2 sRa]
Other_gene_names

[IL2RA; IL2RA; p55; CD25; IL2R; TCGFR; IDDM10]
Specificity

This sandwich ELISA can detect both natural and recombinant human IL-2 sRalpha. This kit exhibits no significant cross-reactivity with factors related to or associated with IL-2 sRalpha such as rhIL-2, rhIL-2 sRalpha. No significant cross-reactivity was observed with recombinant human: IL-1alpha, IL-1beta, IL-1 sRI, IL-1 sRII, IL-1ra, IL-3, IL-3 sR alpha, IL-5, IL-5 sR alpha, IL-5 sRb, IL-6, IL-6 sR, IL-7, IL-8, IL-9, IL-10, IL-11, IL-12, IL-13 ANG, AR, CNTF, beta-ECGR, EGF, EPO, FGF acidic, FGF basic, FGF-4, FGF-5, FGF-6, FGF-7, GCSF, GM-CSF, sgp 130, GRO alpha, GRObeta, GROgamma, HB-EGF, HGF, INF-gamma, IGF-I IGF-II, LAP (TGF-beta1), LIF, M-CSF, MCP-1, MIP-1alpha, MIP-1beta, beta-NGF, OSN, PD-ECGF, PDGFAA, PDGF-AB, PDGF-BB, PTN, RANTES, SCF, SLPI, TGF- alpha, TGF-beta, TNF- alpha, TNF- beta, sTNF RI, sTNF RII, VEGF.
Description

The Interleukin-2 Soluble Receptor alpha (IL-2 sRa) is a α- or alpha protein sometimes glycoprotein present in blood. The receptors are ligand binding factors of type 1, 2 or 3 and protein-molecules that receive chemical-signals from outside a cell. When such chemical-signals couple or bind to a receptor, they cause some form of cellular/tissue-response, e.g. a change in the electrical-activity of a cell. In this sense, am olfactory receptor is a protein-molecule that recognizes and responds to endogenous-chemical signals, chemokinesor cytokines e.g. an acetylcholine-receptor recognizes and responds to its endogenous-ligand, acetylcholine. However, sometimes in pharmacology, the term is also used to include other proteins that are drug-targets, such as enzymes, transporters and ion-channels.

Gene target

Interleukin-2 Soluble Receptor alpha IL-2 sRa
Gene symbol

IL2, IL36G, IL25, IL22, IL18, IL37, IL1RAPL2, IL6R, IL17C, IL17A
Short name

Interleukin-2 Soluble Receptor alpha (IL-2 sRa)
Alternative name

Interleukin-2 Soluble Receptor a (Interleukin-2 sRa)

Gene info

Identity

HGNC:6001
Gene

IL2
Long gene name

interleukin 2
Synonyms
- IL-2
- TCGF
Synonyms name
- T cell growth factor
GenBank acession
- U25676
Locus

4q27
Discovery year

1986-01-01
Entrez gene record

3558
Pubmed identfication
- 3260003
Classification
- Interleukins
VEGA ID

OTTHUMG00000133075

Gene info

Identity

HGNC:15741
Gene

IL36G
Long gene name

interleukin 36 gamma
Synonyms gene
- IL1F9
Synonyms gene name
- interleukin 1 family, member 9
Synonyms
- IL-1H1
- IL-1RP2
- IL-1F9
- IL1H1
- IL1E
Synonyms name
GenBank acession
- AF200492
Locus

2q14.1
Discovery year

2002-08-02
Entrez gene record

56300
Pubmed identfication
- 10860666
- 10744718
- 11991722
- 11991723
RefSeq identity
- NM_019618
Classification
- Interleukins
VEGA ID

OTTHUMG00000131336

Gene info

Identity

HGNC:13765
Gene

IL25
Long gene name

interleukin 25
Synonyms gene
- IL17E
Synonyms gene name
- interleukin 17E
Synonyms
- IL-25
- IL-17E
GenBank acession
- AF305200
Locus

14q11.2
Discovery year

2001-01-26
Pubmed identfication
- 11058597
- 11754819
Classification
- Interleukins
VEGA ID

OTTHUMG00000028749

Gene info

Identity

HGNC:14900
Gene

IL22
Long gene name

interleukin 22
Synonyms
- ILTIF
- IL-21
- zcyto18
- IL-TIF
- IL-D110
- TIFa
- TIFIL-23
- IL-22
- MGC79382
- MGC79384
Synonyms name
- IL-10-related T-cell-derived inducible factor
GenBank acession
- AF279437
Locus

12q15
Discovery year

2001-03-12
Entrez gene record

50616
Pubmed identfication
- 10954742
- 10875937
RefSeq identity
- NM_020525
Classification
- Interleukins
VEGA ID

OTTHUMG00000169119
Locus Specific Databases
- LRG_1248

Gene info

Identity

HGNC:5986
Gene

IL18
Long gene name

interleukin 18
Synonyms gene name
- interleukin 18 (interferon-gamma-inducing factor)
Synonyms
- IGIF
- IL1F4
- IL-1g
- IL-18
Synonyms name
- interferon-gamma-inducing factor
GenBank acession
- U90434
Locus

11q23.1
Discovery year

1997-07-25
Entrez gene record

3606
Pubmed identfication
- 7477296
- 9693051
RefSeq identity
- NM_001562
Classification
- Interleukins
VEGA ID

OTTHUMG00000167006

Gene info

Identity

HGNC:15563
Gene

IL37
Long gene name

interleukin 37
Synonyms gene
- IL1F7
Synonyms gene name
- interleukin 1 family, member 7 (zeta)
Synonyms
- FIL1
- FIL1Z
- FIL1(ZETA)
- IL-1H4
- IL-1RP1
- IL-1F7
Synonyms name
GenBank acession
- AF201832
Locus

2q14.1
Discovery year

2002-08-02
Entrez gene record

27178
Pubmed identfication
RefSeq identity
- NM_014439
Classification
- Interleukins
VEGA ID

OTTHUMG00000131345

Gene info

Identity

HGNC:5997
Gene

IL1RAPL2
Long gene name

interleukin 1 receptor accessory protein like 2
Synonyms
- IL-1R9
- TIGIRR-1
- IL1RAPL-2
- IL1R9
GenBank acession
- AF181285
Locus

Xq22.3
Discovery year

1999-11-19
Entrez gene record

26280
Pubmed identfication
- 10757639
RefSeq identity
- NM_017416
Classification
- TIR domain containing
- Immunoglobulin like domain containing
- Interleukin receptors
VEGA ID

OTTHUMG00000022141
Locus Specific Databases
- Global Variome shared LOVD

Gene info

Identity

HGNC:6019
Gene

IL6R
Long gene name

interleukin 6 receptor
Synonyms
- CD126
- IL-6R
- IL-1Ra
- IL6RA
- gp80
Synonyms name
- membrane glycoprotein 80
- interleukin 6 receptor subunit alpha
GenBank acession
- X12830
Locus

1q21.3
Discovery year

2001-06-22
Entrez gene record

3570
Pubmed identfication
- 8428753
- 12633863
RefSeq identity
- NM_000565
Classification
- CD molecules
- Interleukin receptors
- Immunoglobulin like domain containing
VEGA ID

OTTHUMG00000036073

Gene info

Identity

HGNC:5983
Gene

IL17C
Long gene name

interleukin 17C
Synonyms
- IL-17C
- CX2
- IL-21
- MGC126884
- MGC138401
GenBank acession
- AF152099
Locus

16q24.2
Discovery year

2000-01-20
Entrez gene record

27189
Pubmed identfication
- 10639155
RefSeq identity
- NM_013278
Classification
- Interleukins
VEGA ID

OTTHUMG00000173241

Gene info

Identity

HGNC:5981
Gene

IL17A
Long gene name

interleukin 17A
Synonyms gene
- CTLA8
- IL17
Synonyms gene name
- interleukin 17 (cytotoxic T-lymphocyte-associated serine esterase 8)
Synonyms
- IL-17A
- IL-17
Synonyms name
- cytotoxic T-lymphocyte-associated protein 8
GenBank acession
- U32659
Locus

6p12.2
Discovery year

1993-10-25
Entrez gene record

3605
Pubmed identfication
- 8390535
RefSeq identity
- NM_002190
Classification
- Interleukins
VEGA ID

OTTHUMG00000014840
Locus Specific Databases
- LRG_1223

Interleukin-2 Soluble Receptor alpha (IL-2 sRa)

Gene info

Gene info

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