IL-2Ralpha (CD25) Recombinant monoclonal antibody (Human IgG1 kappa)
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Catalog number
MBS567021
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Price
Please ask
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Size
0.2 mg
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Products_type
Antibody
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Products_short_name
[IL-2Ralpha]
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Other_names
[interleukin-2 receptor subunit alpha; Interleukin-2 receptor subunit alpha; interleukin-2 receptor subunit alpha; p55; IL2-RA; IL-2-RA; TAC antigen; IL-2R subunit alpha; IL-2 receptor subunit alpha; interleukin 2 receptor, alpha; TAC antigen; p55]
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Other_gene_names
[IL2RA; IL2RA; CD25; IL2R; TCGFR; IDDM10; IL-2 receptor subunit alpha; IL-2-RA; IL-2R subunit alpha; IL2-RA]
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Clonality
Monoclonal
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Clone
[Basiliximab]
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Reactivity
Human
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Specificity
Recognizes human IL-2R and binds to the epitope E116RIYHFV122 within the extracellular domain of the CD25 subunit. Binding is abolished when 2 or more residues within the epitope are mutated. This epitope overlaps with the interaction site of CD25 and IL-2. CD25 is found in the high-affinity IL-2R (alphabetagammac) - T cells only express CD25 upon activation. IL-2 binding to IL-2R on T cells modulates proliferation and differentiation
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Purity
Protein A affinity purified
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Form
Liquid. In PBS containing 0.02% Proclin 300
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Storage_stability
For long term storage, store at -20 degree C Stable at 4 degree C for up to 3 months. For longer storage, aliquot and store at -20 degree C. Avoid freeze/thaw cycles Shipping: Shipped on Blue Ice
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Tested_application
Flow Cytometry (FC/FACS), Immunofluorescence (IF), Immunohistochemistry (IHC), Western Blot (WB), Functional Application (FUNC)
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Properties
If you buy Antibodies supplied by MyBioSource they should be stored frozen at - 24°C for long term storage and for short term at + 5°C. Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.
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About
Monoclonals of this antigen are available in different clones. Each murine monoclonal anibody has his own affinity specific for the clone. Mouse monoclonal antibodies are purified protein A or G and can be conjugated to FITC for flow cytometry or FACS and can be of different isotypes.
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Source
Recombinants or rec. proteins
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Group
recombinants
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French translation
anticorps
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Gene target
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Gene symbol
IL36G, IL25, IL22, IL18, IL37, IL6R, IL17C, IL17A, IL17D, IL31
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Short name
IL-2Ralpha (CD25) Recombinant monoclonal antibody ( IgG1 kappa)
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Technique
Recombinant, Antibody, antibodies against human proteins, antibodies for, Monoclonals or monoclonal antibodies, E. coli recombinant proteins are genetic recombinations in Escherichia coli, supplied as white sterile powder lyopillized. MyBioSource advises they will be reconstituted in a buffer soluion or culture medium for cell culture.
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Host
Human
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Isotype
Human IgG1 kappa, IgG1
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Species
Human, Humans
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Alternative name
Interleukin-2Ralpha (CD25) Rec. monoclonal (antibody to-) (H. sapiens IgG1 kappa)
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Alternative technique
rec, antibodies
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Gene info
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Identity
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Gene
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Long gene name
interleukin 36 gamma
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Synonyms gene
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Synonyms gene name
- interleukin 1 family, member 9
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Synonyms
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Synonyms name
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GenBank acession
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Locus
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Discovery year
2002-08-02
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
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VEGA ID
Gene info
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Identity
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Gene
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Long gene name
interleukin 25
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Synonyms gene
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Synonyms gene name
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Synonyms
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GenBank acession
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Locus
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Discovery year
2001-01-26
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Pubmed identfication
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Classification
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VEGA ID
Gene info
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Identity
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Gene
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Long gene name
interleukin 22
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Synonyms
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Synonyms name
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GenBank acession
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Locus
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Discovery year
2001-03-12
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
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VEGA ID
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Locus Specific Databases
Gene info
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Identity
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Gene
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Long gene name
interleukin 18
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Synonyms gene name
- interleukin 18 (interferon-gamma-inducing factor)
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Synonyms
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Synonyms name
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GenBank acession
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Locus
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Discovery year
1997-07-25
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
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VEGA ID
Gene info
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Identity
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Gene
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Long gene name
interleukin 37
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Synonyms gene
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Synonyms gene name
- interleukin 1 family, member 7 (zeta)
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Synonyms
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Synonyms name
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GenBank acession
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Locus
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Discovery year
2002-08-02
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
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VEGA ID
Gene info
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Identity
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Gene
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Long gene name
interleukin 6 receptor
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Synonyms
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Synonyms name
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GenBank acession
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Locus
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Discovery year
2001-06-22
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- CD molecules
- Interleukin receptors
- Immunoglobulin like domain containing
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VEGA ID
Gene info
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Identity
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Gene
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Long gene name
interleukin 17C
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Synonyms
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GenBank acession
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Locus
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Discovery year
2000-01-20
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
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VEGA ID
Gene info
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Identity
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Gene
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Long gene name
interleukin 17A
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Synonyms gene
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Synonyms gene name
- interleukin 17 (cytotoxic T-lymphocyte-associated serine esterase 8)
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Synonyms
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Synonyms name
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GenBank acession
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Locus
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Discovery year
1993-10-25
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
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VEGA ID
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Locus Specific Databases
Gene info
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Identity
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Gene
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Long gene name
interleukin 17D
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Synonyms
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Synonyms name
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GenBank acession
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Locus
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Discovery year
2000-05-02
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
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VEGA ID
Gene info
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Identity
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Gene
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Long gene name
interleukin 31
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Synonyms
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GenBank acession
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Locus
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Discovery year
2003-11-06
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
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VEGA ID
MeSH Data
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Name
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Concept
Scope note:
Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
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Tree numbers
- E05.196.401.143
- E05.301.300.096
- E05.478.566.320.200
- E05.601.262
- E05.601.470.320.200
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Qualifiers
ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data
Product images
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