Human FGFR3 (Fibroblast Growth Factor Receptor 3) Extracellular Domain Recombinant Protein
-
Catalog numberMBS698030
-
PricePlease ask
-
Size1 mg
-
-
Products_typeRecombinant Protein
-
Products_short_name[FGFR3 (Fibroblast Growth Factor Receptor 3)]
-
Products_name_syn[Fibroblast Growth Factor Receptor 3 (IIIc); FGFR3 protein; EC 2.7.10.1; FGFR-3; CD333 antigen; Fibroblast growth factor receptor 3 isoform 1; FGFR3; JTK4;]
-
Other_names[fibroblast growth factor receptor 3 isoform 1; Fibroblast growth factor receptor 3; fibroblast growth factor receptor 3; fibroblast growth factor receptor 3]
-
Products_gene_name[FGFR3]
-
Other_gene_names[FGFR3; FGFR3; ACH; CEK2; JTK4; CD333; HSFGFR3EX; JTK4; FGFR-3]
-
Purity>99%Purification: Fc and 6xHis, Protein A affinity chromatography
-
FormFrozen/Solution; 0.1M Glicina, 50mM Tris, pH 7.4. No preservatives added.
-
Storage_stabilityFor extended storage, conserve at -80 degree C. Repeated freezing and thawing is not recommended. Store working aliquots at 4 degree C for up to one week.
-
Tested_applicationELISA (EIA), Western Blot (WB), Antibody Production, Protein Array
-
DescriptionAplha, transcription related growth factors and stimulating factors or repressing nuclear factors are complex subunits of proteins involved in cell differentiation. Complex subunit associated factors are involved in hybridoma growth, Eosinohils, eritroid proliferation and derived from promotor binding stimulating subunits on the DNA binding complex. NFKB 105 subunit for example is a polypetide gene enhancer of genes in B cells. The receptors are ligand binding factors of type 1, 2 or 3 and protein-molecules that receive chemical-signals from outside a cell. When such chemical-signals couple or bind to a receptor, they cause some form of cellular/tissue-response, e.g. a change in the electrical-activity of a cell. In this sense, am olfactory receptor is a protein-molecule that recognizes and responds to endogenous-chemical signals, chemokinesor cytokines e.g. an acetylcholine-receptor recognizes and responds to its endogenous-ligand, acetylcholine. However, sometimes in pharmacology, the term is also used to include other proteins that are drug-targets, such as enzymes, transporters and ion-channels.
-
PropertiesHuman proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.
-
SourceRecombinants or rec. proteins
-
Grouprecombinants
-
Gene target
-
Gene symbolFGFR3
-
Short nameFGFR3 (Fibroblast Growth Factor Receptor 3) Extracellular Domain Recombinant Protein
-
TechniqueRecombinant, E. coli recombinant proteins are genetic recombinations in Escherichia coli, supplied as white sterile powder lyopillized. MyBioSource advises they will be reconstituted in a buffer soluion or culture medium for cell culture.
-
HostHEK293E Cells
-
SpeciesHuman, Humans
-
Alternative nameH. sapiens FGFR3 (Fibroblast Growth Factor Receptor 3) Extracellular Domain Rec. Protein
-
Alternative techniquerec
-
Gene info
-
Identity
-
Gene
-
Long gene namefibroblast growth factor receptor 3
-
Synonyms gene
-
Synonyms gene name
- achondroplasia, thanatophoric dwarfism
-
Synonyms
-
GenBank acession
-
Locus
-
Discovery year1991-06-07
-
Entrez gene record
-
Pubmed identfication
-
RefSeq identity
-
Classification
- I-set domain containing
- Receptor tyrosine kinases
- CD molecules
-
VEGA ID
-
Locus Specific Databases
MeSH Data
-
Name
-
ConceptScope note: The initial culturing of cells derived directly from fresh TISSUES.
-
Tree numbers
- E01.370.225.500.223.500
- E05.200.500.265.500
- E05.242.223.500
- E05.481.500.249.500
-
Qualifiersethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data