Platelet Derived Growth Factor Receptor alpha, extracellular domain, Recombinant Human (PDGFRA, Platelet-Derived Growth Factor Receptor, alpha polypeptide, Alpha Platelet-Derived Growth Factor Receptor precursor, CD140a, CD140A, CD140a antigen, MGC74795, [Platelet Derived Growth Factor Receptor alpha, extracellular domain Human]

• Catalog number
  MBS638288
• Price
  Please ask
• Size
  NA

• Products_type
  Recombinant Protein
• Description
  The Platelet Derived Growth Factor Receptor alpha, extracellular domain, Recombinant (PDGFRA, Platelet-Derived Growth Factor Receptor, alpha polypeptide, Alpha Platelet-Derived Growth Factor Receptor , CD140a, CD140A, CD140a antigen, MGC74795, [Platelet Derived Growth Factor Receptor alpha, extracellular domain ] is a α- or alpha protein sometimes glycoprotein present in blood. Antigens are peptides or recombinant or native dependent on the production method. Aplha, transcription related growth factors and stimulating factors or repressing nuclear factors are complex subunits of proteins involved in cell differentiation. Complex subunit associated factors are involved in hybridoma growth, Eosinohils, eritroid proliferation and derived from promotor binding stimulating subunits on the DNA binding complex. NFKB 105 subunit for example is a polypetide gene enhancer of genes in B cells. Platelets, also called thrombocytes or cloth cells in blood and are needed to stop bleeding by clumping and clotting the blood the vessels when the an injury occurs. Teh bone marrow will produce the platelets that have no nucleus. Platelates are unique to mammals, the are curved shaped 1900nm to 3100 nm large nucleus free clothing structures. Precursor cell, also called a blast cell or simply blast, is a type of partially differentiated, usually unipotent cell that has lost most or all of the stem cell multipotency. The receptors are ligand binding factors of type 1, 2 or 3 and protein-molecules that receive chemical-signals from outside a cell. When such chemical-signals couple or bind to a receptor, they cause some form of cellular/tissue-response, e.g. a change in the electrical-activity of a cell. In this sense, am olfactory receptor is a protein-molecule that recognizes and responds to endogenous-chemical signals, chemokinesor cytokines e.g. an acetylcholine-receptor recognizes and responds to its endogenous-ligand, acetylcholine. However, sometimes in pharmacology, the term is also used to include other proteins that are drug-targets, such as enzymes, transporters and ion-channels.
• Properties
  Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.
• Source
  Recombinants or rec. proteins
• Group
  recombinants

• Gene target
  Platelet   Derived   Growth   Factor   Receptor   alpha   extracellular   domain   PDGFRA   Platelet-Derived   Growth   Factor   Receptor   alpha   polypeptide   Alpha   Platelet-Derived   Growth   Factor   Receptor   precursor   CD140a   CD140A   CD140a   MGC74795   [Platelet   Derived   Growth   Factor   Receptor   alpha   extracellular   domain  
• Gene symbol
  PDGFRA
• Short name
  Platelet Derived Growth Factor Receptor alpha, extracellular domain, Recombinant (PDGFRA, Platelet-Derived Growth Factor Receptor, alpha polypeptide, Alpha Platelet-Derived Growth Factor Receptor , CD140a, CD140A, CD140a antigen, MGC74795, [Platelet Derived Growth Factor Receptor alpha, extracellular domain ]
• Technique
  Recombinant, antigen, antigenes, E. coli recombinant proteins are genetic recombinations in Escherichia coli, supplied as white sterile powder lyopillized. MyBioSource advises they will be reconstituted in a buffer soluion or culture medium for cell culture.
• Host
  Sf9
• Species
  Human, Humans
• Alternative name
  Platelet Derived Growth Factor Receptor a, extracellular domain, Rec. H. sapiens (platelet-derived growth factor receptor, a polypeptide, Platelet-Derived Growth Factor Receptor, a multipeptide, a Platelet-Derived Growth Factor Receptor precursor, CD140a, CD140A, CD140a protein, MGC74795, [Platelet Derived Growth Factor Receptor a, extracellular domain H. sapiens]
• Alternative technique
  rec, antigenes
• Alternative to gene target
  platelet-derived growth factor receptor, alpha polypeptide, CD140A and PDGFR-2 and PDGFR2 and RHEPDGFRA, PDGFRA and IDBG-18854 and ENSG00000134853 and 5156, transferase activity, nuclei, Pdgfra and IDBG-171929 and ENSMUSG00000029231 and 18595, PDGFRA and IDBG-642308 and ENSBTAG00000007173 and 282301

Gene info

• Identity
  HGNC:8803
• Gene
  PDGFRA
• Long gene name
  platelet derived growth factor receptor alpha
• Synonyms gene name
  • platelet-derived growth factor receptor, alpha polypeptide
• Synonyms
  • CD140a
  • PDGFR2
  • GAS9
• GenBank acession
  • D50001
• Locus
  4q12
• Discovery year
  1989-05-19
• Entrez gene record
  5156
• Pubmed identfication
  • 8643452
• RefSeq identity
  • NM_006206
• Classification
  • I-set domain containing
  • Receptor tyrosine kinases
  • CD molecules
• VEGA ID
  OTTHUMG00000128699
• Locus Specific Databases
  • LRG_309

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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