Human NGF receptor extracellular domain (RECOMBINANT)

Product type

Receptors
Properties

Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.
Description

The receptors are ligand binding factors of type 1, 2 or 3 and protein-molecules that receive chemical-signals from outside a cell. When such chemical-signals couple or bind to a receptor, they cause some form of cellular/tissue-response, e.g. a change in the electrical-activity of a cell. In this sense, am olfactory receptor is a protein-molecule that recognizes and responds to endogenous-chemical signals, chemokinesor cytokines e.g. an acetylcholine-receptor recognizes and responds to its endogenous-ligand, acetylcholine. However, sometimes in pharmacology, the term is also used to include other proteins that are drug-targets, such as enzymes, transporters and ion-channels.
Source

Recombinants or rec. proteins
Group

recombinants

Gene target

NGF receptor extracellular domain
Gene symbol

NGF, NGF-AS1
Short name

NGF receptor extracellular domain (RECOMBINANT)
Technique

Recombinant, E. coli recombinant proteins are genetic recombinations in Escherichia coli, supplied as white sterile powder lyopillized. Austral Biologicals advises they will be reconstituted in a buffer soluion or culture medium for cell culture.
Species

Human, Humans
Alternative name

H. sapiens nerve growth factor (beta polypeptide) receptor extracellular domain (Rec.)
Alternative technique

rec
Alternative to gene target

nerve growth factor (beta polypeptide), Beta-NGF and HSAN5 and NGFB, NGF and IDBG-101347 and ENSG00000134259 and 4803, growth factor activity, Extracellular, Ngf and IDBG-180362 and ENSMUSG00000027859 and 18049, NGF and IDBG-648895 and ENSBTAG00000007446 and 281350

Identity

HGNC:7808
Gene

NGF
Long gene name

nerve growth factor
Synonyms gene
- NGFB
Synonyms gene name
- nerve growth factor (beta polypeptide)
Locus

1p13.2
Discovery year

2001-06-22
Entrez gene record

4803
RefSeq identity
- NM_002506
Classification
- Neurotrophins
VEGA ID

OTTHUMG00000011880
Locus Specific Databases
- Inherited Peripheral Neuropathies Mutation Database
- LRG_260

Name

Primary Cell Culture
Concept

Scope note: The initial culturing of cells derived directly from fresh TISSUES.
Tree numbers
- E01.370.225.500.223.500
- E05.200.500.265.500
- E05.242.223.500
- E05.481.500.249.500
Qualifiers

ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data