CD23, Recombinant, Human (IgE Receptor gp45)
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Catalog number
MBS635898
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Price
Please ask
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Size
0.005 mg
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Products_type
Recombinant Protein
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Products_short_name
[CD23]
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Other_names
[CD23; CD23 protein; Fc receptor, IgE, low affinity II, alpha polypeptide; Fcalpha RII; Fcalpha muR; Fc receptor alpha multiple ligand receptor; Fc fragment of IgE, low affinity II, receptor for (CD23)]
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Other_gene_names
[Fcer2; Fcer2; CD23; Fcer2a; CD23]
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Purity
PurifiedOn SDS-PAGE commassie blue stained gel, the purified recombinant protein shows a band at 48kD
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Form
Supplied as a liquid in 50mM Tris-acetate, pH 7.5, 1mM EDTA and 20% glycerol.
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Storage_stability
-20 degree CStability: Store vial at -20 degree C to -80 degree C. When stored at the recommended temperature, this protein is stable for 12 months. Please avoid freeze-thaw cycles.
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Properties
Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples. Immunoglobulin E (IgE) kappa or Fc specific antibody is a kind of antibody (or immunoglobulin (Ig) "isotype") that has only been found in mammals. IgE is synthesized by plasma cells. Monomers of IgE consist of two heavy chains (ε chain) and two light chains, with the ε chain containing 4 Ig-like constant domains (Cε1-Cε4). IgEs play a role in allergy and response to parasite infection. High levels of IgEs caused by parasites can lower the allergic reaction of patients to allergens common present in the human environment. As such the parasite history of an allergic patient needs to be taken in consideration as a positive factor.
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Description
The receptors are ligand binding factors of type 1, 2 or 3 and protein-molecules that receive chemical-signals from outside a cell. When such chemical-signals couple or bind to a receptor, they cause some form of cellular/tissue-response, e.g. a change in the electrical-activity of a cell. In this sense, am olfactory receptor is a protein-molecule that recognizes and responds to endogenous-chemical signals, chemokinesor cytokines e.g. an acetylcholine-receptor recognizes and responds to its endogenous-ligand, acetylcholine. However, sometimes in pharmacology, the term is also used to include other proteins that are drug-targets, such as enzymes, transporters and ion-channels.
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Source
Recombinants or rec. proteins
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Group
recombinants
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Gene target
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Gene symbol
FCER2
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Short name
CD23, Recombinant, (IgE Receptor gp45)
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Technique
Recombinant, IgE, IgEs, E. coli recombinant proteins are genetic recombinations in Escherichia coli, supplied as white sterile powder lyopillized. MyBioSource advises they will be reconstituted in a buffer soluion or culture medium for cell culture.
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Host
E Coli
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Isotype
IgE, IgE
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Species
Human, Humans
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Alternative name
CD23, Rec., H. sapiens (immunoglobuline E Receptor gp45)
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Alternative technique
rec, immunoglobulin-e
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Gene info
MeSH Data
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Name
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Concept
Scope note:
The initial culturing of cells derived directly from fresh TISSUES.
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Tree numbers
- E01.370.225.500.223.500
- E05.200.500.265.500
- E05.242.223.500
- E05.481.500.249.500
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Qualifiers
ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data
Product images
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