Human IgE
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Catalog numberGWB-A0C883
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Price:
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Size1 vial
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Old catalog number11-511-248621
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Storage temperaturestore cold
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Expiry date1 y
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Categoryresearch antibodies, ELISAs, recombinant proteins, vectors and reagents for laboratory use
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PropertiesHuman proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples. Immunoglobulin E (IgE) kappa or Fc specific antibody is a kind of antibody (or immunoglobulin (Ig) "isotype") that has only been found in mammals. IgE is synthesized by plasma cells. Monomers of IgE consist of two heavy chains (ε chain) and two light chains, with the ε chain containing 4 Ig-like constant domains (Cε1-Cε4). IgEs play a role in allergy and response to parasite infection. High levels of IgEs caused by parasites can lower the allergic reaction of patients to allergens common present in the human environment. As such the parasite history of an allergic patient needs to be taken in consideration as a positive factor.
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Gene target
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Gene symbolFCER2, FCER1G, MS4A2
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Short nameIgE
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TechniqueIgE, IgEs
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IsotypeIgE, IgE
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SpeciesHuman, Humans
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Alternative nameH. sapiens immunoglobuline E
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Alternative techniqueimmunoglobulin-e
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Gene info
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Identity
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Gene
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Long gene nameFc fragment of IgE receptor II
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Synonyms gene
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Synonyms gene name
- Fc fragment of IgE, low affinity II, receptor for (CD23A)
- Fc fragment of IgE, low affinity II, receptor for (CD23)
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Synonyms
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Synonyms name
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GenBank acession
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Locus
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Discovery year1988-08-05
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Entrez gene record
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RefSeq identity
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Classification
- C-type lectin domain containing
- CD molecules
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VEGA ID
Gene info
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Identity
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Gene
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Long gene nameFc fragment of IgE receptor Ig
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Synonyms gene name
- Fc fragment of IgE, high affinity I, receptor for; gamma polypeptide
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Synonyms name
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Locus
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Discovery year1990-08-15
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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VEGA ID
Gene info
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Identity
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Gene
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Long gene namemembrane spanning 4-domains A2
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Synonyms gene
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Synonyms gene name
- IgE responsiveness (atopic)
- membrane-spanning 4-domains, subfamily A, member 2 (Fc fragment of IgE, high affinity I, receptor for; beta polypeptide)
- membrane-spanning 4-domains, subfamily A, member 2
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Synonyms name
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GenBank acession
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Locus
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Discovery year1992-07-09
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Entrez gene record
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Pubmed identfication
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Classification
- Membrane spanning 4-domains
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VEGA ID