Mouse IgE

Old catalog number

11-511-248320
Storage temperature

store cold
Expiry date

1 y
Category

research antibodies, ELISAs, recombinant proteins, vectors and reagents for laboratory use
Properties

Immunoglobulin E (IgE) kappa or Fc specific antibody is a kind of antibody (or immunoglobulin (Ig) "isotype") that has only been found in mammals. IgE is synthesized by plasma cells. Monomers of IgE consist of two heavy chains (ε chain) and two light chains, with the ε chain containing 4 Ig-like constant domains (Cε1-Cε4). IgEs play a role in allergy and response to parasite infection. High levels of IgEs caused by parasites can lower the allergic reaction of patients to allergens common present in the human environment. As such the parasite history of an allergic patient needs to be taken in consideration as a positive factor.
Test

Mouse or mice from the Mus musculus species are used for production of mouse monoclonal antibodies or mabs and as research model for humans in your lab. Mouse are mature after 40 days for females and 55 days for males. The female mice are pregnant only 20 days and can give birth to 10 litters of 6-8 mice a year. Transgenic, knock-out, congenic and inbread strains are known for C57BL/6, A/J, BALB/c, SCID while the CD-1 is outbred as strain.
Latin name

Mus musculus

Identity

HGNC:3612
Gene

FCER2
Long gene name

Fc fragment of IgE receptor II
Synonyms gene
- CD23A
- FCE2
Synonyms gene name
- Fc fragment of IgE, low affinity II, receptor for (CD23A)
- Fc fragment of IgE, low affinity II, receptor for (CD23)
Synonyms
- CLEC4J
- CD23
Synonyms name
- Fc epsilon receptor II
GenBank acession
- M15059
Locus

19p13.2
Discovery year

1988-08-05
Entrez gene record

2208
RefSeq identity
- NM_002002
Classification
- C-type lectin domain containing
- CD molecules
VEGA ID

OTTHUMG00000182517

Identity

HGNC:3611
Gene

FCER1G
Long gene name

Fc fragment of IgE receptor Ig
Synonyms gene name
- Fc fragment of IgE, high affinity I, receptor for; gamma polypeptide
Synonyms name
- Fc epsilon receptor Ig
Locus

1q23.3
Discovery year

1990-08-15
Entrez gene record

2207
Pubmed identfication
- 2138619
RefSeq identity
- NM_004106
VEGA ID

OTTHUMG00000034343

Identity

HGNC:7316
Gene

MS4A2
Long gene name

membrane spanning 4-domains A2
Synonyms gene
- FCER1B
- IGER
- APY
Synonyms gene name
- IgE responsiveness (atopic)
- membrane-spanning 4-domains, subfamily A, member 2 (Fc fragment of IgE, high affinity I, receptor for; beta polypeptide)
- membrane-spanning 4-domains, subfamily A, member 2
Synonyms name
- Fc fragment of IgE, high affinity I, receptor for; beta polypeptide
GenBank acession
- M89796
Locus

11q12.1
Discovery year

1992-07-09
Entrez gene record

2206
Pubmed identfication
- 1386024
Classification
- Membrane spanning 4-domains
VEGA ID

OTTHUMG00000167239