Anti-IL-6 receptor [rhPM-1 (Tocilizumab)]
-
Catalog number
MBS488275
-
Price
Please ask
-
Size
0.2 mg
-
-
Products_type
Recombinant Antibody
-
Products_short_name
[IL-6 receptor]
-
Products_name_syn
[MRA; atlizumab]
-
Products_gene_name
[IL6R]
-
Clonality
Monoclonal
-
Clone
[rhPM-1 (Tocilizumab)]
-
Reactivity
Human
-
Specificity
Tocilizumab binds specifically to both the membrane bound and soluble forms of humanIL-6R. The IL6 receptor is a protein complex consisting of an IL-6 receptor subunit (IL6R) andinterleukin 6 signal transducer Glycoprotein 130. Interleukin 6 (IL6) is a potent pleiotropic cytokinethat regulates cell growth and differentiation and plays an important role in immune response.
-
Purity
Purified Protein A Affinity Purified
-
Storage_stability
Store at 4 degree C for up to 3 months. For longer storage, aliquot and store at -20 degree C.
-
Tested_application
ELISA (EIA), Inhibit
-
Description
This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided. Antibody for research use. The receptors are ligand binding factors of type 1, 2 or 3 and protein-molecules that receive chemical-signals from outside a cell. When such chemical-signals couple or bind to a receptor, they cause some form of cellular/tissue-response, e.g. a change in the electrical-activity of a cell. In this sense, am olfactory receptor is a protein-molecule that recognizes and responds to endogenous-chemical signals, chemokinesor cytokines e.g. an acetylcholine-receptor recognizes and responds to its endogenous-ligand, acetylcholine. However, sometimes in pharmacology, the term is also used to include other proteins that are drug-targets, such as enzymes, transporters and ion-channels.
-
Gene target
-
Gene symbol
IL6, IL6-AS1, IL36G, IL25, IL22, IL18, IL37, IL6R, IL17C, IL17D
-
Short name
Anti-IL-6 receptor [rhPM-1 (Tocilizumab)]
-
Technique
anti-, anti, antibody to, antibodies
-
Isotype
Human IgG1, kappa
-
Alternative name
Antibody toIL-6 receptor [rhPM-1 (Tocilizumab)]
-
Alternative technique
antibodies
-
Gene info
-
Identity
-
Gene
-
Long gene name
interleukin 6
-
Synonyms gene
-
Synonyms gene name
- interleukin 6 (interferon, beta 2)
-
Synonyms
-
Synonyms name
-
GenBank acession
-
Locus
-
Discovery year
1986-01-01
-
Entrez gene record
-
Pubmed identfication
-
RefSeq identity
-
Classification
- Interleukins
- Interferons
- Interleukin 6 type cytokine family
-
VEGA ID
Gene info
-
Identity
-
Gene
-
Long gene name
IL6 antisense RNA 1
-
Locus
-
Discovery year
2019-08-14
-
Entrez gene record
-
RefSeq identity
-
Classification
Gene info
-
Identity
-
Gene
-
Long gene name
interleukin 36 gamma
-
Synonyms gene
-
Synonyms gene name
- interleukin 1 family, member 9
-
Synonyms
-
Synonyms name
-
GenBank acession
-
Locus
-
Discovery year
2002-08-02
-
Entrez gene record
-
Pubmed identfication
-
RefSeq identity
-
Classification
-
VEGA ID
Gene info
-
Identity
-
Gene
-
Long gene name
interleukin 25
-
Synonyms gene
-
Synonyms gene name
-
Synonyms
-
GenBank acession
-
Locus
-
Discovery year
2001-01-26
-
Pubmed identfication
-
Classification
-
VEGA ID
Gene info
-
Identity
-
Gene
-
Long gene name
interleukin 22
-
Synonyms
-
Synonyms name
-
GenBank acession
-
Locus
-
Discovery year
2001-03-12
-
Entrez gene record
-
Pubmed identfication
-
RefSeq identity
-
Classification
-
VEGA ID
-
Locus Specific Databases
Gene info
-
Identity
-
Gene
-
Long gene name
interleukin 18
-
Synonyms gene name
- interleukin 18 (interferon-gamma-inducing factor)
-
Synonyms
-
Synonyms name
-
GenBank acession
-
Locus
-
Discovery year
1997-07-25
-
Entrez gene record
-
Pubmed identfication
-
RefSeq identity
-
Classification
-
VEGA ID
Gene info
-
Identity
-
Gene
-
Long gene name
interleukin 37
-
Synonyms gene
-
Synonyms gene name
- interleukin 1 family, member 7 (zeta)
-
Synonyms
-
Synonyms name
-
GenBank acession
-
Locus
-
Discovery year
2002-08-02
-
Entrez gene record
-
Pubmed identfication
-
RefSeq identity
-
Classification
-
VEGA ID
Gene info
-
Identity
-
Gene
-
Long gene name
interleukin 6 receptor
-
Synonyms
-
Synonyms name
-
GenBank acession
-
Locus
-
Discovery year
2001-06-22
-
Entrez gene record
-
Pubmed identfication
-
RefSeq identity
-
Classification
- CD molecules
- Interleukin receptors
- Immunoglobulin like domain containing
-
VEGA ID
Gene info
-
Identity
-
Gene
-
Long gene name
interleukin 17C
-
Synonyms
-
GenBank acession
-
Locus
-
Discovery year
2000-01-20
-
Entrez gene record
-
Pubmed identfication
-
RefSeq identity
-
Classification
-
VEGA ID
Gene info
-
Identity
-
Gene
-
Long gene name
interleukin 17D
-
Synonyms
-
Synonyms name
-
GenBank acession
-
Locus
-
Discovery year
2000-05-02
-
Entrez gene record
-
Pubmed identfication
-
RefSeq identity
-
Classification
-
VEGA ID
MeSH Data
-
Name
-
Concept
Scope note:
Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
-
Tree numbers
- E05.196.401.143
- E05.301.300.096
- E05.478.566.320.200
- E05.601.262
- E05.601.470.320.200
-
Qualifiers
ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data
Similar products
