Anti - Angiotensin II Type 1 Receptor (AT1)

• Catalog number
  MBS619726
• Price
  Please ask
• Size
  0.1 mL

• Products_type
  Antibody
• Products_short_name
  [Angiotensin II Type 1 Receptor]
• Products_name_syn
  [Angiotensin II Type 1 Receptor (AT1)]
• Other_names
  [angiotensin II type 1 receptor; Type-1 angiotensin II receptor; type-1 angiotensin II receptor; AT1; angiotensin II type 1 receptor; angiotensin II type-1 receptor; Angiotensin II type-1 receptor]
• Other_gene_names
  [AGTR1; AGTR1; AT1-R]
• Clonality
  Polyclonal
• Reactivity
  Human, Mouse, Porcine, Rabbit, Rat
• Specificity
  The 10 AA rat immunogenic peptide is 100% identical in mouse, rat, human, porcine and rabbit. The sequence is the same in all AT II receptor isoforms (Type 1a, 1b and 1c). It has no sequence homology with other G-protein coupled receptors. Actual crossreactivity of antibodies in all species is not established
• Purity
  Serum
• Form
  Serum Supplied as a liquid, neat serum, 40% glycerol.
• Storage_stability
  May be stored at 4 degree C for short-term only. For long-term storage, store at -20 degree C. Aliquots are stable for at least 12 months at -20 degree C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
• Tested_application
  ELISA, Western Blot
• Description
  This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided. The receptors are ligand binding factors of type 1, 2 or 3 and protein-molecules that receive chemical-signals from outside a cell. When such chemical-signals couple or bind to a receptor, they cause some form of cellular/tissue-response, e.g. a change in the electrical-activity of a cell. In this sense, am olfactory receptor is a protein-molecule that recognizes and responds to endogenous-chemical signals, chemokinesor cytokines e.g. an acetylcholine-receptor recognizes and responds to its endogenous-ligand, acetylcholine. However, sometimes in pharmacology, the term is also used to include other proteins that are drug-targets, such as enzymes, transporters and ion-channels.

• Gene target
  Angiotensin   Receptor   AT1  
• Gene symbol
  PGR-AS1, SLC33A1, AGTR1, PLAAT1
• Short name
  Anti - Angiotensin II 1 Receptor (AT1)
• Technique
  anti, antibody to
• Host
  Host: Chicken Source: Rat
• Isotype
  IgY
• Alternative name
  antibody to - Angiotensin II classification 1 Receptor (AT1)
• Alternative technique
  antibodies

Gene info

• Identity
  HGNC:52650
• Gene
  PGR-AS1
• Long gene name
  PGR antisense RNA 1
• Synonyms
  • AT1
  • AT2
  • AT3
• Synonyms name
  • PR-antisense-transcripts
• Locus
  11q22.1
• Discovery year
  2016-11-24
• Entrez gene record
  101054525
• Pubmed identfication
  • 18604220
• RefSeq identity
  • NR_073144
• Classification
  • Antisense RNAs
• VEGA ID
  OTTHUMG00000167532

Gene info

• Identity
  HGNC:95
• Gene
  SLC33A1
• Long gene name
  solute carrier family 33 member 1
• Synonyms gene
  • ACATN
  • SPG42
• Synonyms gene name
  • acetyl-Coenzyme A transporter
  • spastic paraplegia 42 (autosomal dominant)
  • solute carrier family 33 (acetyl-CoA transporter), member 1
• Synonyms
  • AT-1
  • AT1
• GenBank acession
  • D88152
• Locus
  3q25.31
• Discovery year
  1999-02-12
• Entrez gene record
  9197
• Pubmed identfication
  • 9096318
  • 19061983
• RefSeq identity
  • NM_004733
• Classification
  • Solute carriers
• VEGA ID
  OTTHUMG00000158481

Gene info

• Identity
  HGNC:336
• Gene
  AGTR1
• Long gene name
  angiotensin II receptor type 1
• Synonyms gene
  • AGTR1B
• Synonyms gene name
  • angiotensin receptor 1B
• Synonyms
  • AT1
  • AT2R1
  • AGTR1A
  • AT2R1A
  • HAT1R
  • AG2S
  • AT2R1B
  • AT1B
• GenBank acession
  • M87290
• Locus
  3q24
• Discovery year
  1992-08-25
• Entrez gene record
  185
• Pubmed identfication
  • 1550596
• Classification
  • Angiotensin receptors
• VEGA ID
  OTTHUMG00000159503

Gene info

• Identity
  HGNC:14922
• Gene
  PLAAT1
• Long gene name
  phospholipase A and acyltransferase 1
• Synonyms gene
  • HRASLS
• Synonyms gene name
  • HRAS like suppressor
• Synonyms
  • H-REV107
  • HRASLS1
  • A-C1
  • PLA/AT1
  • PLAAT-1
• Synonyms name
  • phospholipase A/acyltransferase 1
• GenBank acession
  • AB030816
• Locus
  3q29
• Discovery year
  2001-04-10
• Entrez gene record
  57110
• Pubmed identfication
  • 21880860
• Classification
  • Phospholipase A and acyltransferase family
• VEGA ID
  OTTHUMG00000156104

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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