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Also known as
Angiotensin II, Type 1 Receptor
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Other names
angiotensinogen preproprotein; Angiotensinogen; angiotensinogen; serpin A8; angiotensin I; angiotensin II; pre-angiotensinogen; alpha-1 antiproteinase, antitrypsin; serine (or cysteine) proteinase inhibitor; angiotensinogen (serpin peptidase inhibitor, clade A, member 8); Serpin A8Cleaved into the following 8 chains:Angiotensin-1; Alternative name(s):; Angiotensin 1-10; Angiotensin I; Ang IAngiotensin-2; Alternative name(s):; Angiotensin 1-8; Angiotensin II; Ang IIAngiotensin-3; Alternative name(s):; Angiotensin 2-8; Angiotensin III; Ang III; Des-Asp[1]-angiotensin IIAngiotensin-4; Alternative name(s):; Angiotensin 3-8; Angiotensin IV
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Category
Antibodies
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Subcategory
Mnoclonal antibodies
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Gene name
AGT; AGT; ANHU; SERPINA8; SERPINA8; Ang I; Ang II; Ang III; Ang IV
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Gene name synonims
AGT; AGT; ANHU; SERPINA8; SERPINA8; Ang I; Ang II; Ang III; Ang IV
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Other gene names
AGT; AGT; ANHU; SERPINA8; SERPINA8; Ang I; Ang II; Ang III; Ang IV
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Clonality
Monoclonal
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Immunoglobulin isotype
IgG1,k
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Clone
3H296
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Host organism
Mouse (Mus musculus)
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Source organism
Rat (Rattus norvegicus)
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Species reactivity
Human (Homo sapiens), Rat (Rattus norvegicus); Due to limited knowledge and inability for testing each and every species, the reactivity of the antibody may extend to other species which are not listed hereby.
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Specificity and cross reactivity
Recognizes Angiotensin II, Type 1 receptor, both the recombinant form as well as that expressed on transfected CHO cells and rat smooth muscle cells. Species Crossreactivity: human and rat.; Since it is not possible to test each and every species our knowledge on the corss reactivity of the antibodies is limited. This particular antibody might cross react with speacies outside of the listed ones.
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Purification method
Affinity Purified by Protein A affinity chromatography.
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Form Appearance
Supplied as a liquid in 0.15M PBS. No preservative added.
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Concentration
N/A
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Storage and shipping
Store the antibody at +4 degrees Celsius for short term storage.. Aliquot to avoid repeated freezing and thawing. For optimal long term storage, the antibody should be kept at -20 degrees Celsius. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
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Tested applications
ELISA (EL/EIA)
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Description
The receptors are ligand binding factors of type 1, 2 or 3 and protein-molecules that receive chemical-signals from outside a cell. When such chemical-signals couple or bind to a receptor, they cause some form of cellular/tissue-response, e.g. a change in the electrical-activity of a cell. In this sense, am olfactory receptor is a protein-molecule that recognizes and responds to endogenous-chemical signals, chemokinesor cytokines e.g. an acetylcholine-receptor recognizes and responds to its endogenous-ligand, acetylcholine. However, sometimes in pharmacology, the term is also used to include other proteins that are drug-targets, such as enzymes, transporters and ion-channels.