Angiotensin II Type 1 Receptor Antibody

• Catalog number
  bs-2097R
• Price
  Please ask
• Size
  0.1ml

• Long name
  Angiotensin II Type 1 Receptor Antibody
• Also known as
  Angiotensin II Type 1 Receptor Antibody
• Category
  Primary Antibodies
• Conjugation
  Unconjugated
• Target Antigen
  Angiotensin II Type 1 Receptor
• Specificity
  This is a highly specific antibody against Angiotensin II Type 1 Receptor.
• Modification s
  None
• Modification site s
  Unmodified antibody
• Clonality
  Polyclonal antibody
• Clone number
  Polyclonal antibody
• Concentration
  1ug per 1ul
• Subcellular location
  Cytoplasm
• Source
  This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human AT1R
• Gene ID number
  185
• Tested Applications
  WB, IHC-P, IF(IHC-P)
• Recommended dilutions
  WB(1:100-1000), IHC-P(1:100-500), IF(IHC-P)(1:50-200)
• Cross reactivity
  Human, Mouse, Rat
• Cross reactive species details
  Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.
• Background of the target antigen
  Angiotensin II is a potent vasopressor hormone and a primary regulator of aldosterone secretion. It is an important effector controlling blood pressure and volume in the cardiovascular system. It acts through at least two types of receptors. This gene encodes the type 1 receptor which is thought to mediate the major cardiovascular effects of angiotensin II. This gene may play a role in the generation of reperfusion arrhythmias following restoration of blood flow to ischemic or infarcted myocardium. It was previously thought that a related gene, denoted as AGTR1B, existed; however, it is now believed that there is only one type 1 receptor gene in humans. At least five transcript variants have been described for this gene. Additional variants have been described but their full-length nature has not been determined. The entire coding sequence is contained in the terminal exon and is present in all transcript variants. [provided by RefSeq].
• Purification method
  This antibody was purified via Protein A.
• Storage conditions
  Keep the antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store at -20°C for up to 1 year.
• Synonym names
  AG2S; Agtr 1; Agtr1; Agtr1a; AGTR1B; Angiotensin II receptor type 1; Angiotensin II type 1 receptor; AT-1B; AT-1r; AT1; At1a; AT1AR; AT1B; AT1BR; AT2R1; AT2R1A; AT2R1B; HAT1R; Type 1 angiotensin II receptor; AGTR1_HUMAN; Type-1 angiotensin II receptor; Angiotensin II type-1 receptor; AT1R; Ang II; Angiotensin II receptor type 1; Angiotensin II type 1 receptor; Angiotensin receptor 1; Angiotensin receptor 1B; AT 1B; AT1; AT1R.
• Properties
  If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• Description
  The receptors are ligand binding factors of type 1, 2 or 3 and protein-molecules that receive chemical-signals from outside a cell. When such chemical-signals couple or bind to a receptor, they cause some form of cellular/tissue-response, e.g. a change in the electrical-activity of a cell. In this sense, am olfactory receptor is a protein-molecule that recognizes and responds to endogenous-chemical signals, chemokinesor cytokines e.g. an acetylcholine-receptor recognizes and responds to its endogenous-ligand, acetylcholine. However, sometimes in pharmacology, the term is also used to include other proteins that are drug-targets, such as enzymes, transporters and ion-channels.
• French translation
  anticorps

• Gene target
  Angiotensin   Receptor  
• Gene symbol
  AGTR1, APLNR, FBXW7-AS1
• Short name
  Anti-Angiotensin II Type 1 Receptor
• Technique
  Antibody, antibodies against human proteins, antibodies for
• Host
  Rabbit (Oryctolagus cuniculus)
• Isotype
  Immunoglobulin G (IgG)
• Alternative name
  Angiotensin II Type 1 Receptor Antibody
• Alternative technique
  antibodies

Gene info

• Identity
  HGNC:336
• Gene
  AGTR1
• Long gene name
  angiotensin II receptor type 1
• Synonyms gene
  • AGTR1B
• Synonyms gene name
  • angiotensin receptor 1B
• Synonyms
  • AT1
  • AT2R1
  • AGTR1A
  • AT2R1A
  • HAT1R
  • AG2S
  • AT2R1B
  • AT1B
• GenBank acession
  • M87290
• Locus
  3q24
• Discovery year
  1992-08-25
• Entrez gene record
  185
• Pubmed identfication
  • 1550596
• Classification
  • Angiotensin receptors
• VEGA ID
  OTTHUMG00000159503

Gene info

• Identity
  HGNC:339
• Gene
  APLNR
• Long gene name
  apelin receptor
• Synonyms gene
  • AGTRL1
• Synonyms gene name
  • angiotensin II receptor-like 1
• Synonyms
  • FLJ90771
  • APJ
  • APJR
• Synonyms name
  • APJ (apelin) receptor
• GenBank acession
  • U03642
• Locus
  11q12.1
• Discovery year
  1994-07-07
• Entrez gene record
  187
• Pubmed identfication
  • 8294032
  • 14622440
• RefSeq identity
  • NM_005161
• VEGA ID
  OTTHUMG00000167021

Gene info

• Identity
  HGNC:52397
• Gene
  FBXW7-AS1
• Long gene name
  FBXW7 antisense RNA 1
• Synonyms
  • DEAR
  • DEspR
• Synonyms name
  • dual-endothelin1/VEGFsp receptor
  • dual endothelin-1(VEGFsp)/angiotensin II receptor
• Locus
  4q31.3
• Discovery year
  2016-10-13
• Entrez gene record
  102191832
• Classification
  • Antisense RNAs
• VEGA ID
  OTTHUMG00000185247

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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