a1-Antitrypsin (AAT, alpha1 Proteinase Inhibitor, alpha1 PI)

• Catalog number
  MBS610859
• Price
  Please ask
• Size
  5x1 mg

• Products_type
  Antibody
• Products_short_name
  [a1-Antitrypsin]
• Products_name_syn
  [Anti -a1-Antitrypsin (AAT, alpha1 Proteinase Inhibitor, alpha1 PI)]
• Other_names
  [alpha-1-antitrypsin; Alpha-1-antitrypsin; alpha-1-antitrypsin; serpin A1; alpha-1-antiproteinase; alpha-1-antitrypsin null; alpha-1 protease inhibitor; protease inhibitor 1 (anti-elastase), alpha-1-antitrypsin; serine (or cysteine) proteinase inhibitor, clade A, member 1; serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1; Alpha-1 protease inhibitor; Alpha-1-antiproteinase; Serpin A1]
• Other_gene_names
  [SERPINA1; SERPINA1; PI; A1A; AAT; PI1; A1AT; PRO2275; alpha1AT; AAT; PI; SPAAT]
• Clonality
  Polyclonal
• Reactivity
  Human
• Specificity
  Specific for alpha1AT as demonstrated by immunoelectrophoresis. A single precipitin arc is observed with normal plasma of identical mobility to that obtained with purified alpha1AT.
• Purity
  Purified Purified by caprylic acid and ammonium sulfate precipitations, and solid -phase adsorption to remove unwanted crossreactivity.
• Form
  Supplied in 10mM HEPES, pH7.4, 0.1M sodium chloride and 50% glycerol.
• Storage_stability
  May be stored at 4 degree C for short-term only. For long-term storage, store at -20 degree C. Aliquots are stable for at least 12 months at -20 degree C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
• Description
  Tissue, pathway, proteinase, peptidase, protease ,acrosin, lipoprotein, activator, caspase, trypsin, papain, esterase inhibitors are proteins or receptor ligands or receptor antagonists that bind to an enzyme receptor and decreases its activity. Since blocking an enzyme's activity can kill a pathogen or correct a metabolic imbalance, many drugs are enzyme inhibitors. Not all receptor antagonist that bind to enzymes are inhibitors; enzyme activator ligands or agonists bind to enzymes and increase their enzymatic activity, while enzyme substrates bind and are converted to products in the normal catalytic cycle of the enzyme.

• Gene target
  a1-Antitrypsin   AAT   alpha1   Proteinase   Inhibitor   alpha1  
• Gene symbol
  TRI-AAT1-1, TRI-AAT4-1, TRI-AAT7-1, TRI-AAT3-1, TRI-AAT11-1, TRI-AAT7-2, TRI-AAT12-1, TRI-AAT2-1, TRI-AAT6-1, TRI-AAT8-1
• Short name
  a1-Antitrypsin (AAT, alpha1 Proteinase Inhibitor, alpha1 PI)
• Host
  Goat
• Isotype
  IgG
• Alternative name
  a1-Antitrypsin (AAT, alpha1 Proteinase suppressor, alpha1 PI)

Gene info

• Identity
  HGNC:34812
• Gene
  TRI-AAT1-1
• Long gene name
  tRNA-Ile (anticodon AAT) 1-1
• Synonyms gene
  • TRNAI12
• Synonyms gene name
  • transfer RNA isoleucine 12 (anticodon AAU)
  • transfer RNA-Ile (AAT) 1-1
• Synonyms
  • tRNA-Ile-AAT-1-1
• GenBank acession
  • HG983843
• Locus
  6p11.2
• Discovery year
  2008-08-29
• Entrez gene record
  100189249
• Classification
  • Cytoplasmic transfer RNAs

Gene info

• Identity
  HGNC:34961
• Gene
  TRI-AAT4-1
• Long gene name
  tRNA-Ile (anticodon AAT) 4-1
• Synonyms gene
  • TRNAI24
• Synonyms gene name
  • transfer RNA isoleucine 24 (anticodon AAU)
  • transfer RNA-Ile (AAT) 4-1
• Synonyms
  • tRNA-Ile-AAT-4-1
• GenBank acession
  • HG983846
• Locus
  17p13.1
• Discovery year
  2008-08-29
• Entrez gene record
  100189393
• Classification
  • Cytoplasmic transfer RNAs

Gene info

• Identity
  HGNC:34710
• Gene
  TRI-AAT7-1
• Long gene name
  tRNA-Ile (anticodon AAT) 7-1
• Synonyms gene
  • TRNAI8
• Synonyms gene name
  • transfer RNA isoleucine 8 (anticodon AAU)
  • transfer RNA-Ile (AAT) 7-1
• Synonyms
  • tRNA-Ile-AAT-7-1
• GenBank acession
  • HG983853
• Locus
  6p22.2
• Discovery year
  2008-08-29
• Entrez gene record
  100189401
• Classification
  • Cytoplasmic transfer RNAs

Gene info

• Identity
  HGNC:34776
• Gene
  TRI-AAT3-1
• Long gene name
  tRNA-Ile (anticodon AAT) 3-1
• Synonyms gene
  • TRNAI11
• Synonyms gene name
  • transfer RNA isoleucine 11 (anticodon AAU)
  • transfer RNA-Ile (AAT) 3-1
• Synonyms
  • tRNA-Ile-AAT-3-1
• GenBank acession
  • HG983845
• Locus
  6p22.1
• Discovery year
  2008-08-29
• Entrez gene record
  100189213
• Classification
  • Cytoplasmic transfer RNAs

Gene info

• Identity
  HGNC:35047
• Gene
  TRI-AAT11-1
• Long gene name
  tRNA-Ile (anticodon AAT) 11-1
• Synonyms gene
  • TRNAI29P
• Synonyms gene name
  • transfer RNA isoleucine 29 (anticodon AAU) pseudogene
  • transfer RNA-Ile (AAT) 11-1
• Synonyms
  • tRNA-Ile-AAT-11-1
• GenBank acession
  • HG983858
• Locus
  12q24.33
• Discovery year
  2008-08-29
• Entrez gene record
  100189474
• RefSeq identity
  • NG_008532
• Classification
  • Cytoplasmic transfer RNA pseudogenes

Gene info

• Identity
  HGNC:34970
• Gene
  TRI-AAT7-2
• Long gene name
  tRNA-Ile (anticodon AAT) 7-2
• Synonyms gene
  • TRNAI25
• Synonyms gene name
  • transfer RNA isoleucine 25 (anticodon AAU)
  • transfer RNA-Ile (AAT) 7-2
• Synonyms
  • tRNA-Ile-AAT-7-2
• GenBank acession
  • HG983854
• Locus
  6p22.2
• Discovery year
  2008-08-29
• Entrez gene record
  107986683
• Classification
  • Cytoplasmic transfer RNAs

Gene info

• Identity
  HGNC:35054
• Gene
  TRI-AAT12-1
• Long gene name
  tRNA-Ile (anticodon AAT) 12-1
• Synonyms gene
  • TRNAI30P
• Synonyms gene name
  • transfer RNA isoleucine 30 (anticodon AAU) pseudogene
  • transfer RNA-Ile (AAT) 12-1
• Synonyms
  • tRNA-Ile-AAT-12-1
• GenBank acession
  • HG983859
• Locus
  20q13.2
• Discovery year
  2008-08-29
• Entrez gene record
  100189481
• Classification
  • Cytoplasmic transfer RNAs

Gene info

• Identity
  HGNC:34630
• Gene
  TRI-AAT2-1
• Long gene name
  tRNA-Ile (anticodon AAT) 2-1
• Synonyms gene
  • TRNAI4
• Synonyms gene name
  • transfer RNA isoleucine 4 (anticodon AAU)
  • transfer RNA-Ile (AAT) 2-1
• Synonyms
  • tRNA-Ile-AAT-2-1
• GenBank acession
  • HG983844
• Locus
  6p22.1
• Discovery year
  2008-08-29
• Entrez gene record
  100189071
• Classification
  • Cytoplasmic transfer RNAs

Gene info

• Identity
  HGNC:34940
• Gene
  TRI-AAT6-1
• Long gene name
  tRNA-Ile (anticodon AAT) 6-1
• Synonyms gene
  • TRNAI22
• Synonyms gene name
  • transfer RNA isoleucine 22 (anticodon AAU)
  • transfer RNA-Ile (AAT) 6-1
• Synonyms
  • tRNA-Ile-AAT-6-1
• GenBank acession
  • HG983852
• Locus
  6p22.2
• Discovery year
  2008-08-29
• Entrez gene record
  100189372
• Classification
  • Cytoplasmic transfer RNAs

Gene info

• Identity
  HGNC:34656
• Gene
  TRI-AAT8-1
• Long gene name
  tRNA-Ile (anticodon AAT) 8-1
• Synonyms gene
  • TRNAI5
• Synonyms gene name
  • transfer RNA isoleucine 5 (anticodon AAU)
  • transfer RNA-Ile (AAT) 8-1
• Synonyms
  • tRNA-Ile-AAT-8-1
• GenBank acession
  • HG983855
• Locus
  6p22.1
• Discovery year
  2008-08-29
• Entrez gene record
  100189095
• Classification
  • Cytoplasmic transfer RNAs

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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