Alpha1 Antitrypsin Antibody

  • Catalog number
    7009-30T
  • Price
    Please ask
  • Size
    30 µg
  • Antibody Target
    Alpha1 Antitrypsin
  • Target Alternative Name
    Alpha-1 protease inhibitor, Alpha-1-antiproteinase, Serpin A1, AAT, PI
  • Antibody Type
    Polyclonal
  • Species Reactivities
    Human, Mouse, Rat
  • Immunogen Sequence
    Human alpha1 antitrypsin (Cat # 7294)
  • Accession
    P01009
  • Gene Id
    5265
  • Appearance
    Colorless liquid
  • Form
    Liquid
  • Concentration
    0.5 mg/ml
  • Formulation
    30 µg (0.5 mg/ml) of antibody in PBS pH 7.2, 0.01 % BSA, 0.03 % ProClin®, and 50 % glycerol.
  • Purification
    Affinity purified rabbit IgG
  • Application
    Western blot
  • Positive Control
    Western blot: h serum, m muscle, rat kidney, h alpha1 antitrypsin
  • Application And Usages
    Western blot: 1-4 µg
  • Description
    Alpha 1 Antitrypsin is an acute-phase plasma protein found at 290 mg per 100 ml. It functions as a serine protease inhibitor with targets like elastase, plasmin, collagenase, thrombin, leucocyte proteases, trypsin, chymotrypsin, and plasminogen activator. Clinically, its deficiency is associated with two major diseases: pulmonary emphysema and early onset/juvenile hepatic cirrhosis. It is elevated in inflammatory conditions, malignancies, liver disease and pregnancy and also after surgical trauma and use of oral contraceptives. The simultaneous quantitative determination of alpha-1-PI and ceruloplasmin permits differential diagnosis of liver afflictions. Rise in alpha 1 antitrypsin occurs as an acute phase response to tissue necrosis and inflammation.
  • Storage Condition
    -20°C
  • Shipping Condition
    gel pack
  • Shelf Life
    12 months
  • Usage
    For Research Use Only! Not to be used in humans.
  • Handling
    The antibody solution should be gently mixed before use.
  • Western Blot Verified
    Verified
  • Immunocytochemistry Verified
    Not Verified
  • Immunofluorescence Verified
    Not Verified
  • Immunoprecipitation Verified
    Not Verified
  • ELISA Verified
    Not Verified
  • ChIP Verified
    Not Verified
  • Dot Blot Verified
    Not Verified
  • Flow Cytometry Verified
    Not Verified
  • Properties
    If you buy Antibodies supplied by Biovision they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
  • French translation
    anticorps
  • Gene target
  • Short name
    Alpha1 Antitrypsin Antibody
  • Technique
    Antibody, antibodies against human proteins, antibodies for
  • Isotype
    rabbit IgG
  • Alternative name
    Alpha1 Antitrypsin (antibody to-)
  • Alternative technique
    antibodies
MeSH Data
  • Name
  • Concept
    Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
  • Tree numbers
    • E05.196.401.143
    • E05.301.300.096
    • E05.478.566.320.200
    • E05.601.262
    • E05.601.470.320.200
  • Qualifiers
    ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data
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