a1-Antitrypsin (AAT, alpha1 Proteinase Inhibitor, alpha1 PI)
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Catalog numberMBS610859
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PricePlease ask
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Size1 mg
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Products_typeAntibody
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Products_short_name[a1-Antitrypsin]
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Products_name_syn[Anti -a1-Antitrypsin (AAT, alpha1 Proteinase Inhibitor, alpha1 PI)]
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Other_names[alpha-1-antitrypsin; Alpha-1-antitrypsin; alpha-1-antitrypsin; serpin A1; alpha-1-antiproteinase; alpha-1-antitrypsin null; alpha-1 protease inhibitor; protease inhibitor 1 (anti-elastase), alpha-1-antitrypsin; serine (or cysteine) proteinase inhibitor, clade A, member 1; serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1; Alpha-1 protease inhibitor; Alpha-1-antiproteinase; Serpin A1]
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Other_gene_names[SERPINA1; SERPINA1; PI; A1A; AAT; PI1; A1AT; PRO2275; alpha1AT; AAT; PI; SPAAT]
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ClonalityPolyclonal
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ReactivityHuman
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SpecificitySpecific for alpha1AT as demonstrated by immunoelectrophoresis. A single precipitin arc is observed with normal plasma of identical mobility to that obtained with purified alpha1AT.
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PurityPurified Purified by caprylic acid and ammonium sulfate precipitations, and solid -phase adsorption to remove unwanted crossreactivity.
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FormSupplied in 10mM HEPES, pH7.4, 0.1M sodium chloride and 50% glycerol.
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Storage_stabilityMay be stored at 4 degree C for short-term only. For long-term storage, store at -20 degree C. Aliquots are stable for at least 12 months at -20 degree C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
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DescriptionTissue, pathway, proteinase, peptidase, protease ,acrosin, lipoprotein, activator, caspase, trypsin, papain, esterase inhibitors are proteins or receptor ligands or receptor antagonists that bind to an enzyme receptor and decreases its activity. Since blocking an enzyme's activity can kill a pathogen or correct a metabolic imbalance, many drugs are enzyme inhibitors. Not all receptor antagonist that bind to enzymes are inhibitors; enzyme activator ligands or agonists bind to enzymes and increase their enzymatic activity, while enzyme substrates bind and are converted to products in the normal catalytic cycle of the enzyme.
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Gene target
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Gene symbolTRI-AAT1-1, TRI-AAT4-1, TRI-AAT7-1, TRI-AAT3-1, TRI-AAT11-1, TRI-AAT7-2, TRI-AAT12-1, TRI-AAT2-1, TRI-AAT6-1, TRI-AAT8-1
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Short namea1-Antitrypsin (AAT, alpha1 Proteinase Inhibitor, alpha1 PI)
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HostGoat
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IsotypeIgG
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Alternative namea1-Antitrypsin (AAT, alpha1 Proteinase suppressor, alpha1 PI)
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Gene info
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Identity
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Gene
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Long gene nametRNA-Ile (anticodon AAT) 1-1
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Synonyms gene
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Synonyms gene name
- transfer RNA isoleucine 12 (anticodon AAU)
- transfer RNA-Ile (AAT) 1-1
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Synonyms
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GenBank acession
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Locus
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Discovery year2008-08-29
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Entrez gene record
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Classification
- Cytoplasmic transfer RNAs
Gene info
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Identity
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Gene
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Long gene nametRNA-Ile (anticodon AAT) 4-1
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Synonyms gene
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Synonyms gene name
- transfer RNA isoleucine 24 (anticodon AAU)
- transfer RNA-Ile (AAT) 4-1
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Synonyms
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GenBank acession
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Locus
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Discovery year2008-08-29
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Entrez gene record
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Classification
- Cytoplasmic transfer RNAs
Gene info
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Identity
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Gene
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Long gene nametRNA-Ile (anticodon AAT) 7-1
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Synonyms gene
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Synonyms gene name
- transfer RNA isoleucine 8 (anticodon AAU)
- transfer RNA-Ile (AAT) 7-1
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Synonyms
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GenBank acession
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Locus
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Discovery year2008-08-29
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Entrez gene record
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Classification
- Cytoplasmic transfer RNAs
Gene info
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Identity
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Gene
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Long gene nametRNA-Ile (anticodon AAT) 3-1
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Synonyms gene
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Synonyms gene name
- transfer RNA isoleucine 11 (anticodon AAU)
- transfer RNA-Ile (AAT) 3-1
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Synonyms
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GenBank acession
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Locus
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Discovery year2008-08-29
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Entrez gene record
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Classification
- Cytoplasmic transfer RNAs
Gene info
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Identity
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Gene
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Long gene nametRNA-Ile (anticodon AAT) 11-1
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Synonyms gene
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Synonyms gene name
- transfer RNA isoleucine 29 (anticodon AAU) pseudogene
- transfer RNA-Ile (AAT) 11-1
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Synonyms
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GenBank acession
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Locus
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Discovery year2008-08-29
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Entrez gene record
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RefSeq identity
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Classification
- Cytoplasmic transfer RNA pseudogenes
Gene info
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Identity
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Gene
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Long gene nametRNA-Ile (anticodon AAT) 7-2
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Synonyms gene
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Synonyms gene name
- transfer RNA isoleucine 25 (anticodon AAU)
- transfer RNA-Ile (AAT) 7-2
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Synonyms
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GenBank acession
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Locus
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Discovery year2008-08-29
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Entrez gene record
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Classification
- Cytoplasmic transfer RNAs
Gene info
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Identity
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Gene
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Long gene nametRNA-Ile (anticodon AAT) 12-1
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Synonyms gene
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Synonyms gene name
- transfer RNA isoleucine 30 (anticodon AAU) pseudogene
- transfer RNA-Ile (AAT) 12-1
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Synonyms
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GenBank acession
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Locus
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Discovery year2008-08-29
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Entrez gene record
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Classification
- Cytoplasmic transfer RNAs
Gene info
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Identity
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Gene
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Long gene nametRNA-Ile (anticodon AAT) 2-1
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Synonyms gene
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Synonyms gene name
- transfer RNA isoleucine 4 (anticodon AAU)
- transfer RNA-Ile (AAT) 2-1
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Synonyms
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GenBank acession
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Locus
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Discovery year2008-08-29
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Entrez gene record
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Classification
- Cytoplasmic transfer RNAs
Gene info
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Identity
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Gene
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Long gene nametRNA-Ile (anticodon AAT) 6-1
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Synonyms gene
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Synonyms gene name
- transfer RNA isoleucine 22 (anticodon AAU)
- transfer RNA-Ile (AAT) 6-1
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Synonyms
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GenBank acession
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Locus
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Discovery year2008-08-29
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Entrez gene record
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Classification
- Cytoplasmic transfer RNAs
Gene info
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Identity
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Gene
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Long gene nametRNA-Ile (anticodon AAT) 8-1
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Synonyms gene
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Synonyms gene name
- transfer RNA isoleucine 5 (anticodon AAU)
- transfer RNA-Ile (AAT) 8-1
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Synonyms
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GenBank acession
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Locus
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Discovery year2008-08-29
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Entrez gene record
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Classification
- Cytoplasmic transfer RNAs
MeSH Data
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Name
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ConceptScope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
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Tree numbers
- E05.196.401.143
- E05.301.300.096
- E05.478.566.320.200
- E05.601.262
- E05.601.470.320.200
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Qualifiersethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data