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Alternative name1
Anti-Platelet Derived Growth Factor Receptor Type B, phosphorylated (PDGFRb)
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Alternative name2
Platelet Derived Growth Factor Receptor Type B, phosphorylated (PDGFRb)
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Alternative name3
Platelet Derived Growth Factor Receptor Type B, phosphorylated (PDGFRb)
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Alternative name4
Platelet Derived Growth Factor Receptor Type B
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Alternative name5
Anti -Platelet Derived Growth Factor Receptor Type B, phosphorylated (PDGFRb)
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Other names
platelet-derived growth factor receptor; Beta-type platelet-derived growth factor receptor; beta-type platelet-derived growth factor receptor; PDGF-R-beta; OTTHUMP00000160528; CD140 antigen-like family member B; platelet-derived growth factor receptor, beta polypeptide; CD140 antigen-like family member B
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Gene name
N/A
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Gene name synonims
N/A
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Other gene names
PDGFRB; PDGFRB; JTK12; PDGFR; CD140B; PDGFR1; N/A
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Category
Antibodies
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Clonality
Polyclonal
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Immunoglobulin isotype
IgG
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Clone
Polyclonal antibody
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Host organism
Host: Rabbit; Source: Human
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Species reactivity
Human, Mouse, Rat
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Specificity and cross reactivity
Recognizes PDGFR b phosphorylated at Y716, Mr 190kDa; an unknown protein was also recognized, Mr 66kDa. Shows crossreactivity with the phosphorylated EGF receptor. Species Crossreactivity: Mouse; predicted to crossreact with human and rat based on conservation of immunogenic sequence.
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Purification method
Affinity Purified by Protein A affinity chromatography.
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Form Appearance
Supplied as 200ug in 200ul of 0.1M Tris-glycine, pH 7.4, 0.15M sodium chloride, 0.05% sodium azide, 30% glycerol.
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Concentration
N/A
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Storage and shipping
Stable for 2 years productone should be stored at -20 degrees Celsius. from date of shipment. For maximum recovery of product, centrifuge the vial prior to removing the cap.
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Tested for
Western Blot (WB), Immunoprecipitation (IP)
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Description
productone is a polyclonal antibody of high purity and binding affinity for the antigen that it is risen against. Properly used, this antibody will ensure excellent and reproducible results with guaranteed success for the applications that it is tested in. Polyclonal antibodies have series of advantages - larger batches can be supplied at a time, they are inexpensive to manufacture and respectively to buy, the time needed for production is considerably shorter. Polyclonal antibodies generally are more stable and retain their reactivity under unfavorable conditions. To obtain more detailed information on productone, please, refer to the full product datasheet.
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Advisory
In order to retain the quality and the affinity of productone unchanged, please, avoid cycles of freezing and thawing. For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube. Prior to use briefly centrifuge the vial to gather all the solution on the bottom.
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Additional description
Aplha, transcription related growth factors and stimulating factors or repressing nuclear factors are complex subunits of proteins involved in cell differentiation. Complex subunit associated factors are involved in hybridoma growth, Eosinohils, eritroid proliferation and derived from promotor binding stimulating subunits on the DNA binding complex. NFKB 105 subunit for example is a polypetide gene enhancer of genes in B cells. Platelets, also called thrombocytes or cloth cells in blood and are needed to stop bleeding by clumping and clotting the blood the vessels when the an injury occurs. Teh bone marrow will produce the platelets that have no nucleus. Platelates are unique to mammals, the are curved shaped 1900nm to 3100 nm large nucleus free clothing structures. The receptors are ligand binding factors of type 1, 2 or 3 and protein-molecules that receive chemical-signals from outside a cell. When such chemical-signals couple or bind to a receptor, they cause some form of cellular/tissue-response, e.g. a change in the electrical-activity of a cell. In this sense, am olfactory receptor is a protein-molecule that recognizes and responds to endogenous-chemical signals, chemokinesor cytokines e.g. an acetylcholine-receptor recognizes and responds to its endogenous-ligand, acetylcholine. However, sometimes in pharmacology, the term is also used to include other proteins that are drug-targets, such as enzymes, transporters and ion-channels.
