-
Also known as
Platelet Derived Growth Factor Receptor, Type B
-
Other names
platelet-derived growth factor receptor; Beta-type platelet-derived growth factor receptor; beta-type platelet-derived growth factor receptor; PDGF-R-beta; OTTHUMP00000160528; CD140 antigen-like family member B; platelet-derived growth factor receptor, beta polypeptide; CD140 antigen-like family member B
-
Category
Antibodies
-
Subcategory
Mnoclonal antibodies
-
Gene name
PDGFRB; PDGFRB; JTK12; PDGFR; CD140B; PDGFR1; N/A
-
Gene name synonims
PDGFRB; PDGFRB; JTK12; PDGFR; CD140B; PDGFR1; N/A
-
Other gene names
PDGFRB; PDGFRB; JTK12; PDGFR; CD140B; PDGFR1; N/A
-
Clonality
Monoclonal
-
Immunoglobulin isotype
IgG
-
Clone
10F652
-
Host organism
Rabbit (Oryctolagus cuniculus)
-
Source organism
Mouse (Mus musculus)
-
Species reactivity
N/A; Due to limited knowledge and inability for testing each and every species, the reactivity of the antibody may extend to other species which are not listed hereby.
-
Specificity and cross reactivity
Recognizes mouse phospho-PDGF Receptor beta (Tyr857).; Since it is not possible to test each and every species our knowledge on the corss reactivity of the antibodies is limited. This particular antibody might cross react with speacies outside of the listed ones.
-
Purification method
Supernatant
-
Form Appearance
Supplied as a liquid in PBS, 50mM Tris-Glycine, pH 7.4, 0.15 M NaCl, 40% glycerol, 0.01% sodium azide, 0.05% BSA.
-
Concentration
N/A
-
Storage and shipping
Store the antibody at +4 degrees Celsius for short term storage.. Aliquot to avoid repeated freezing and thawing. For optimal long term storage, the antibody should be kept at -20 degrees Celsius. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
-
Tested applications
Western Blot (WB)
-
Description
Antigens are peptides or recombinant or native dependent on the production method. Aplha, transcription related growth factors and stimulating factors or repressing nuclear factors are complex subunits of proteins involved in cell differentiation. Complex subunit associated factors are involved in hybridoma growth, Eosinohils, eritroid proliferation and derived from promotor binding stimulating subunits on the DNA binding complex. NFKB 105 subunit for example is a polypetide gene enhancer of genes in B cells. Platelets, also called thrombocytes or cloth cells in blood and are needed to stop bleeding by clumping and clotting the blood the vessels when the an injury occurs. Teh bone marrow will produce the platelets that have no nucleus. Platelates are unique to mammals, the are curved shaped 1900nm to 3100 nm large nucleus free clothing structures. The receptors are ligand binding factors of type 1, 2 or 3 and protein-molecules that receive chemical-signals from outside a cell. When such chemical-signals couple or bind to a receptor, they cause some form of cellular/tissue-response, e.g. a change in the electrical-activity of a cell. In this sense, am olfactory receptor is a protein-molecule that recognizes and responds to endogenous-chemical signals, chemokinesor cytokines e.g. an acetylcholine-receptor recognizes and responds to its endogenous-ligand, acetylcholine. However, sometimes in pharmacology, the term is also used to include other proteins that are drug-targets, such as enzymes, transporters and ion-channels.
-
Gene target
-
Gene symbol
PDGFRB, PDGFA
-
Short name
Platelet Derived Growth Factor Receptor, B, phosphorylated (Tyr857) (PDGF Receptor beta, PDGFRb, CD140b Antigen, JTK12, PDGFR1)
-
Technique
antigen, antigenes
-
Alternative name
Anti-Platelet Derived Growth Factor Receptor, Type B, phosphorylated (Tyr857) (PDGF Receptor beta, PDGFRb, CD140b Antigen, JTK12, PDGFR1)
-
Alternative technique
antigenes
-
Alternative to gene target
platelet-derived growth factor receptor, beta polypeptide, CD140B and IBGC4 and IMF1 and JTK12 and PDGFR and PDGFR-1 and PDGFR1, PDGFRB and IDBG-53326 and ENSG00000113721 and 5159, transferase activity, nuclei, Pdgfrb and IDBG-150834 and ENSMUSG00000024620 and 18596, BT.74208 and IDBG-646273 and ENSBTAG00000002804 and 527165
-
