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Alternative name1
Anti-NFkB Activating Kinase, CT (Nuclear Factor kappa B, TANK-Binding Kinase 1, NAK, TBK1)
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Alternative name2
NFkB Activating Kinase, CT (Nuclear Factor kappa B, TANK-Binding Kinase 1, NAK, TBK1)
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Alternative name3
NFkB Activating Kinase, CT (Nuclear Factor kappa B, TANK-Binding Kinase 1, NAK, TBK1)
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Alternative name4
NFkB Activating Kinase
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Alternative name5
Anti -NFkB Activating Kinase, CT (Nuclear Factor kappa B, TANK-Binding Kinase 1, NAK, TBK1)
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Other names
NEDD4 family-interacting protein 1; NEDD4 family-interacting protein 1; NEDD4 family-interacting protein 1; Nedd4 WW domain-binding protein 5; putative MAPK-activating protein PM13; breast cancer-associated protein SGA-1M; putative NFKB and MAPK-activating protein; putative NF-kappa-B-activating protein 164; Nedd4 family interacting protein 1; Breast cancer-associated protein SGA-1M; NEDD4 WW domain-binding protein 5; Putative MAPK-activating protein PM13; Putative NF-kappa-B-activating protein 164; Putative NFKB and MAPK-activating protein
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Gene name
N/A
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Gene name synonims
N/A
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Other gene names
NDFIP1; NDFIP1; N4WBP5; N4WBP5
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Category
Antibodies
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Clonality
Polyclonal
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Immunoglobulin isotype
IgG
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Clone
Polyclonal antibody
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Host organism
Host: Rabbit; Source: Human
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Species reactivity
Human, Mouse, Rat
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Specificity and cross reactivity
Recognizes human NF-kB-activating kinase (NAK), otherwise known as TANK-binding kinase 1 (TBK1). Does not cross-react with IKK Alpha, IKK Beta, IKK Gamma or IKK Epsilon. Species Crossreactivity: mouse, rat
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Purification method
Affinity Purified by immunoaffinity chromatography.
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Form Appearance
Supplied as a liquid in PBS, 0.02% sodium azide.
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Concentration
N/A
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Storage and shipping
Store at 4 degrees Celsius for short term storage.. For long-term storage and to avoid repeated freezing and thawing, aliquot and For optimal long term storage, productone should be kept at -20 degrees Celsius. Aliquots are stable for at least 12 months productone should be stored at -20 degrees Celsius.. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
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Tested for
Western Blot (WB), Immunohistochemistry (IHC)
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Description
productone is a polyclonal antibody of high purity and binding affinity for the antigen that it is risen against. Properly used, this antibody will ensure excellent and reproducible results with guaranteed success for the applications that it is tested in. Polyclonal antibodies have series of advantages - larger batches can be supplied at a time, they are inexpensive to manufacture and respectively to buy, the time needed for production is considerably shorter. Polyclonal antibodies generally are more stable and retain their reactivity under unfavorable conditions. To obtain more detailed information on productone, please, refer to the full product datasheet.
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Advisory
In order to retain the quality and the affinity of productone unchanged, please, avoid cycles of freezing and thawing. For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube. Prior to use briefly centrifuge the vial to gather all the solution on the bottom.
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Properties
If you buy Antibodies supplied by MBS Polyclonals they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
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Additional description
Aplha, transcription related growth factors and stimulating factors or repressing nuclear factors are complex subunits of proteins involved in cell differentiation. Complex subunit associated factors are involved in hybridoma growth, Eosinohils, eritroid proliferation and derived from promotor binding stimulating subunits on the DNA binding complex. NFKB 105 subunit for example is a polypetide gene enhancer of genes in B cells.
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Gene
NF-κB (nuclear factor kappa-light-chain-enhancer of activated B cells) is a protein complex that controls transcription of DNA, cytokine production and cell survival. NF-κB is found in almost all animal cell types and is involved in cellular responses to stimuli such as stress, cytokines, free radicals, ultraviolet irradiation, oxidized LDL, and bacterial or viral antigens. NF-κB plays a key role in regulating the immune response to infection (κ light chains are critical components of immunoglobulins). Incorrect regulation of NF-κB has been linked to cancer, inflammatory and autoimmune diseases, septic shock, viral infection, and improper immune development. NF-κB has also been implicated in processes of synaptic plasticity and memory
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French translation
anticorps
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Gene target
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Gene symbol
TBK1, TANK-AS1, TANK, NR4A1
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Short name
NFkB Activating Kinase, CT ( Factor kappa B, TANK-Binding Kinase 1, NAK, TBK1) Antibody
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Technique
Antibody, antibodies against human proteins, antibodies for
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Alternative name
NFkB Activating phosphorylation catalyst, CT (Nuclear Factor kappa B, TANK-Binding phosphorylation catalyst 1, NAK, TANK-binding kinase 1) (antibody to-)
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Alternative technique
antibodies
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Alternative to gene target
TANK-binding kinase 1, TBK1 and IDBG-44993 and ENSG00000183735 and 29110, transferase activity, Cytoplasm, Tbk1 and IDBG-192882 and ENSMUSG00000020115 and 56480, TBK1 and IDBG-634420 and ENSBTAG00000017401 and 533141
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