NFkB Activating Kinase (Nuclear Factor kappa B, TANK-Binding Kinase 1, NAK, TBK1)
#
-
Catalog numberMBS604330
-
Price:
-
Size0,1 mg
-
-
Other sizeplease contact us to order other different size
-
DescriptionAplha, transcription related growth factors and stimulating factors or repressing nuclear factors are complex subunits of proteins involved in cell differentiation. Complex subunit associated factors are involved in hybridoma growth, Eosinohils, eritroid proliferation and derived from promotor binding stimulating subunits on the DNA binding complex. NFKB 105 subunit for example is a polypetide gene enhancer of genes in B cells.
-
GeneNF-κB (nuclear factor kappa-light-chain-enhancer of activated B cells) is a protein complex that controls transcription of DNA, cytokine production and cell survival. NF-κB is found in almost all animal cell types and is involved in cellular responses to stimuli such as stress, cytokines, free radicals, ultraviolet irradiation, oxidized LDL, and bacterial or viral antigens. NF-κB plays a key role in regulating the immune response to infection (κ light chains are critical components of immunoglobulins). Incorrect regulation of NF-κB has been linked to cancer, inflammatory and autoimmune diseases, septic shock, viral infection, and improper immune development. NF-κB has also been implicated in processes of synaptic plasticity and memory
-
Gene target
-
Gene symbolTBK1, TANK-AS1, TANK, NR4A1
-
Short nameNFkB Activating Kinase ( Factor kappa B, TANK-Binding Kinase 1, NAK, TBK1)
-
Alternative nameNFkB Activating phosphorylation catalyst (Nuclear Factor kappa B, TANK-Binding phosphorylation catalyst 1, NAK, TANK-binding kinase 1)
-
Alternative to gene targetTANK-binding kinase 1, TBK1 and IDBG-44993 and ENSG00000183735 and 29110, transferase activity, Cytoplasm, Tbk1 and IDBG-192882 and ENSMUSG00000020115 and 56480, TBK1 and IDBG-634420 and ENSBTAG00000017401 and 533141
-
Gene info
-
Identity
-
Gene
-
Long gene nameTANK binding kinase 1
-
Synonyms gene name
- TANK-binding kinase 1
-
Synonyms
-
GenBank acession
-
Locus
-
Discovery year2000-06-08
-
Entrez gene record
-
Pubmed identfication
-
RefSeq identity
-
Classification
- I kappa B kinases
-
VEGA ID
-
Locus Specific Databases
Gene info
-
Identity
-
Gene
-
Long gene nameTANK antisense RNA 1
-
Locus
-
Discovery year2020-03-27
-
Entrez gene record
-
Classification
- Antisense RNAs
Gene info
-
Identity
-
Gene
-
Long gene nameTRAF family member associated NFKB activator
-
Synonyms gene
-
Synonyms gene name
- TRAF family member-associated NFKB activator
-
Synonyms
-
GenBank acession
-
Locus
-
Discovery year1997-06-12
-
Entrez gene record
-
Pubmed identfication
-
RefSeq identity
-
VEGA ID
Gene info
-
Identity
-
Gene
-
Long gene namenuclear receptor subfamily 4 group A member 1
-
Synonyms gene
-
Synonyms gene name
- nuclear receptor subfamily 4, group A, member 1
-
Synonyms
-
GenBank acession
-
Locus
-
Discovery year1990-09-10
-
Entrez gene record
-
Pubmed identfication
-
Classification
- Nuclear receptor subfamily 4 group A
-
VEGA ID