Anti-APAF1 (aa12-28)
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Catalog numberMBS223169
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PricePlease ask
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Size50ug
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Alternative name1Anti-RABBIT ANTI APAF1 (aa12-28)
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Alternative name2RABBIT ANTI APAF1 (aa12-28)
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Alternative name3Lapin ANTI APAF1 (aa12-28)
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Alternative name4APAF1
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Alternative name5N/A
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Other namesapoptotic protease-activating factor 1 isoform b; Apoptotic protease-activating factor 1; apoptotic protease-activating factor 1; apoptotic peptidase activating factor 1; N/A
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Gene nameAPAF1
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Gene name synonimsN/A
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Other gene namesAPAF1; APAF1; CED4; APAF-1; KIAA0413; APAF-1
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CategoryAntibodies
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ClonalityPolyclonal
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Immunoglobulin isotypePolyclonal IgG
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ClonePolyclonal antibody
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Host organismRabbit
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Species reactivityHuman
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Specificity and cross reactivityAPAF1 Apaf1 (Apoptosis protease activating factor 1) is the mammalian homologue of the CED-4 cell death protein in C. Elegans. Apaf1 binds to cytochrome C and caspase-9 leading to caspase-9 activation, resulting in the beginning of the proteolytic cascade characteristic of apoptosis. Apaf1 can also associate with caspase-4 and caspase-8. MBS221594 recognises a 130kD band in Western blots.
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Purification methodN/A
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Form AppearancePurified (Purified IgG - liquid)
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ConcentrationIgG concentration 0.5 mg/ml
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Storage and shippingStore at +Store productone at +4 degrees Celsius. or productone should be stored at -20 degrees Celsius. if preferred. productone should be stored undiluted. Avoid repeated freezing and thawing as this may denature the antibody. Should productone contain a precipitate we recommend microcentrifugation before use. Shelf Life: 18 months from date of dispatch.
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Tested forImmunohistology - Paraffin (IHC), Western Blot (WB)
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Descriptionproductone is a polyclonal antibody of high purity and binding affinity for the antigen that it is risen against. Properly used, this antibody will ensure excellent and reproducible results with guaranteed success for the applications that it is tested in. Polyclonal antibodies have series of advantages - larger batches can be supplied at a time, they are inexpensive to manufacture and respectively to buy, the time needed for production is considerably shorter. Polyclonal antibodies generally are more stable and retain their reactivity under unfavorable conditions. To obtain more detailed information on productone, please, refer to the full product datasheet.
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AdvisoryIn order to retain the quality and the affinity of productone unchanged, please, avoid cycles of freezing and thawing. For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube. Prior to use briefly centrifuge the vial to gather all the solution on the bottom.
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Additional descriptionThis antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided. Antibody for research use.
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Gene target
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Gene symbolAPAF1
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Short nameAnti-APAF1 (aa12-28)
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Techniqueanti-, anti, antibody to, antibodies
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Alternative nameAntibody toAPAF1 (aa12-28)
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Alternative techniqueantibodies
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Alternative to gene targetapoptotic peptidase activating factor 1, APAF-1 and CED4, APAF1 and IDBG-52364 and ENSG00000120868 and 317, ADP binding, nuclei, Apaf1 and IDBG-185032 and ENSMUSG00000019979 and 11783, APAF1 and IDBG-636787 and ENSBTAG00000021661 and 537782
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Gene info
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Identity
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Gene
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Long gene nameapoptotic peptidase activating factor 1
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Synonyms gene name
- apoptotic protease activating factor
- apoptotic peptidase activating factor
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Synonyms
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GenBank acession
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Locus
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Discovery year1998-01-20
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- Apoptosome
- WD repeat domain containing
- Caspase recruitment domain containing
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VEGA ID
MeSH Data
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Name
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ConceptScope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
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Tree numbers
- E05.196.401.143
- E05.301.300.096
- E05.478.566.320.200
- E05.601.262
- E05.601.470.320.200
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Qualifiersethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data