RABBIT ANTI APAF1 (aa12-28)
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Catalog number
MBS221594
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Price
Please ask
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Size
5x0.1 mg
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Products_type
Antibody
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Products_short_name
[APAF1]
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Other_names
[apoptotic protease-activating factor 1 isoform b; Apoptotic protease-activating factor 1; apoptotic protease-activating factor 1; apoptotic peptidase activating factor 1]
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Products_gene_name
[APAF1]
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Other_gene_names
[APAF1; APAF1; CED4; APAF-1; KIAA0413; APAF-1]
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Clonality
Polyclonal
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Reactivity
Mouse
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Specificity
Apaf1 (Apoptosis protease activating factor 1) is the mammalian homologue of the CED-4 cell death protein in C. Elegans. Apaf1 binds to cytochrome C and caspase-9 leading to caspase-9 activation, resulting in the beginning of the proteolytic cascade characteristic of apoptosis. Apaf1 can also associate with caspase-4 and caspase-8. This item recognises a 130kD band in Western blots.
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Form
Purified Purified IgG - liquid
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Concentration
IgG concentration 0.5 mg/ml
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Storage_stability
Store at 4 degree C or at -20 degree C if preferred. This product should be stored undiluted. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use. Shelf Life: 18 months from date of despatch.
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Tested_application
Immunohistology Paraffin*, Western Blot (WB)
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Description
This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided.
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About
Rabbits are used for polyclonal antibody production by MyBioSource. Rabbit antibodies are very stable and can be stored for several days at room temperature. MyBioSource adds sodium azide and glycerol to enhance the stability of the rabbit polyclonal antibodies. Anti-human, anti mouse antibodies to highly immunogenic selected peptide sequences are" monoclonal like" since the epitope to which they are directed is less than 35 amino acids long.
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Latin name
Oryctolagus cuniculus
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Gene target
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Gene symbol
APAF1
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Short name
RABBIT ANTI APAF1 (aa12-28)
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Technique
Rabbit, anti, antibody to
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Host
Rabbit, Rabbits
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Isotype
IgG
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Alternative name
production species: rabbit antibody to apoptotic peptidase activating factor 1 (aa12-28)
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Alternative technique
rabbit-anti, antibodies
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Alternative to gene target
apoptotic peptidase activating factor 1, APAF-1 and CED4, APAF1 and IDBG-52364 and ENSG00000120868 and 317, ADP binding, nuclei, Apaf1 and IDBG-185032 and ENSMUSG00000019979 and 11783, APAF1 and IDBG-636787 and ENSBTAG00000021661 and 537782
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Gene info
MeSH Data
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Name
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Concept
Scope note:
Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
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Tree numbers
- E05.196.401.143
- E05.301.300.096
- E05.478.566.320.200
- E05.601.262
- E05.601.470.320.200
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Qualifiers
ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data
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