Mouse Anti-Melanoma Associated Antigen

• Catalog number
  GEN570276
• Price
  Please ask
• Size
  1 mililiter

• Also known as
  Melanoma Associated Antigen
• Other names
  melanoma-associated antigen; N/A
• Category
  Antibodies
• Subcategory
  Mnoclonal antibodies
• Gene name
  N/A
• Gene name synonims
  N/A
• Other gene names
  N/A
• Clonality
  Monoclonal
• Immunoglobulin isotype
  IgG2b
• Clone
  NKI-Beteb
• Host organism
  Mouse (Mus musculus)
• Species reactivity
  Human (Homo sapiens); Due to limited knowledge and inability for testing each and every species, the reactivity of the antibody may extend to other species which are not listed hereby.
• Specificity and cross reactivity
  NKI-Beteb reacts with Melanoma Associated Antigen, a glycoprotein of 100 + 7 kDa. Melanoma associated antigen (MAA) is dispersed in the cytoplasma of melanoma cells, and is more concentRated inside vacuoles and sometimes on the melanosomes. Occasionally the antigen is seen on the cell surface. The antigen is actively shed from living cells. Melanoma Associated Antigen 100 + 7 kDa is present in melanomas, clear cells sarcomas (melanoma of soft tissue), nevocellular nevi, and normal melanocytes. Except for one case of non Hodgkin's lymphoma in which macrophages were positive, the antigen has not been detected with other tumors or tissues observed. The antibody reacts with melanomas, clear cell sarcomas (melanoma of soft tissue), nevocellular nevi, and normal melanocytes. The antibody reacts with melanomas, clear cell sarcomas (melanoma of soft tissue), nevocellular nevi, and normal melanocytes.; Since it is not possible to test each and every species our knowledge on the corss reactivity of the antibodies is limited. This particular antibody might cross react with speacies outside of the listed ones.
• Purification method
  N/A
• Form Appearance
  Each vial contains 1ml of culture supernatant of monoclonal antibody containing 0.09% sodium azide.
• Concentration
  N/A
• Storage and shipping
  Store the antibody at +4 degrees Celsius., or in small aliquots the antibody should be stored at -20 degrees Celsius..
• Tested applications
  Immunohistochemistry (IHC) (frozen), Immunohistochemistry (IHC) (paraffin)
• Description
  This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided. Antibody for research use. Antigens are peptides or recombinant or native dependent on the production method.
• Test
  Mouse or mice from the Mus musculus species are used for production of mouse monoclonal antibodies or mabs and as research model for humans in your lab. Mouse are mature after 40 days for females and 55 days for males. The female mice are pregnant only 20 days and can give birth to 10 litters of 6-8 mice a year. Transgenic, knock-out, congenic and inbread strains are known for C57BL/6, A/J, BALB/c, SCID while the CD-1 is outbred as strain.
• Latin name
  Mus musculus

• Gene target
  Melanoma   Associated  
• Gene symbol
  MAGEA1, CSPG4, MAGED2
• Short name
  Mouse Anti-Melanoma Associated Antigen
• Technique
  antigen, anti-, Mouse, anti, antibody to, antibodies, antigenes, mouses
• Host
  mouse
• Species
  Mouse, Mouses
• Alternative name
  Anti-Mouse anti Melanoma Associated Antigen
• Alternative technique
  antigenes, murine, antibodies

Gene info

• Identity
  HGNC:6796
• Gene
  MAGEA1
• Long gene name
  MAGE family member A1
• Synonyms gene
  • MAGE1
• Synonyms gene name
  • melanoma antigen family A, 1 (directs expression of antigen MZ2-E)
  • melanoma antigen family A1
• Synonyms
  • MGC9326
  • CT1.1
• Synonyms name
  • melanoma-associated antigen 1
  • melanoma-associated antigen MZ2-E
  • melanoma antigen MAGE-1
  • melanoma antigen family A 1
  • cancer/testis antigen family 1, member 1
• Locus
  Xq28
• Discovery year
  1994-04-04
• Entrez gene record
  4100
• Pubmed identfication
  • 1840703
  • 25590999
• RefSeq identity
  • NM_004988
• Classification
  • MAGE family
• VEGA ID
  OTTHUMG00000024192
• Locus Specific Databases
  • Global Variome shared LOVD

Gene info

• Identity
  HGNC:2466
• Gene
  CSPG4
• Long gene name
  chondroitin sulfate proteoglycan 4
• Synonyms gene name
  • chondroitin sulfate proteoglycan 4 (melanoma-associated)
• Synonyms
  • MCSPG
  • MEL-CSPG
  • MSK16
  • NG2
  • MCSP
  • HMW-MAA
  • CSPG4A
• Synonyms name
  • melanoma-associated chondroitin sulfate proteoglycan
• GenBank acession
  • X96753
  • AY359468
• Locus
  15q24.2
• Discovery year
  1997-11-28
• Entrez gene record
  1464
• Pubmed identfication
  • 8790396
  • 16407841
• RefSeq identity
  • NM_001897
• Classification
  • Proteoglycans
• VEGA ID
  OTTHUMG00000142836

Gene info

• Identity
  HGNC:16353
• Gene
  MAGED2
• Long gene name
  MAGE family member D2
• Synonyms gene name
  • melanoma antigen family D2
• Synonyms
  • JCL-1
  • BCG1
  • 11B6
  • MAGE-D2
  • HCA10
  • MAGED
  • MGC8386
• Synonyms name
  • hepatocellular carcinoma associated protein
  • breast cancer associated gene 1
  • melanoma-associated antigen D2
  • hepatocellular carcinoma-associated protein HCA10
• GenBank acession
  • AF128527
• Locus
  Xp11.21
• Discovery year
  2001-08-16
• Entrez gene record
  10916
• RefSeq identity
  • NM_014599
• Classification
  • MAGE family
  • Small nucleolar RNA protein coding host genes
• VEGA ID
  OTTHUMG00000021638
• Locus Specific Databases
  • Global Variome shared LOVD

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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