anti-mouse IL-17A mAb MT2270, biotinylated

Categories

Antibodies
Description

This monoclonal antibody enables sensitive and specific detection of mouse IL-17A in immunoassays such as ELISA and ELISpot.
Recommandation

We recommend MT2270 as detection antibody in ELISA and ELISpot in combination with capture antibody IL17-I.
Antibody Clone

MT2270
Enzyme Conjugate

biotin
Format

biotinylated
Application

ELISA, ELISpot
Reactivities

mouse
Analytes

IL17A
Specificity

Native and recombinant IL-17A
Contents

MT2270, biotinylated, supplied at 0.5 mg/ml in PBS with 0.02% sodium azide
Datasheet
Product Header

Monoclonal antibody specific for IL-17A
Shelf Life

18 months
Additional description

This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided. Antibody for research use.
Test

Mouse or mice from the Mus musculus species are used for production of mouse monoclonal antibodies or mabs and as research model for humans in your lab. Mouse are mature after 40 days for females and 55 days for males. The female mice are pregnant only 20 days and can give birth to 10 litters of 6-8 mice a year. Transgenic, knock-out, congenic and inbread strains are known for C57BL/6, A/J, BALB/c, SCID while the CD-1 is outbred as strain.
Latin name

Mus musculus

Gene target

IL-17A mAb MT2270 biotinylated
Gene symbol

IL17A, IL36G, IL25, IL22, IL18, IL37, IL6R, IL17C, IL17D, IL31
Short name

anti-mouse IL-17A mAb MT2270, biotinylated
Technique

anti-, Mouse, anti, antibody to, antibodies, mouses
Host

Mouse
Isotype

IgG1
Species

Mouse, Mouses
Alternative name

Antibody tomouse Interleukin-17A monoclonal MT2270, biotinylated
Alternative technique

murine, antibodies

Identity

HGNC:5981
Gene

IL17A
Long gene name

interleukin 17A
Synonyms gene
- CTLA8
- IL17
Synonyms gene name
- interleukin 17 (cytotoxic T-lymphocyte-associated serine esterase 8)
Synonyms
- IL-17A
- IL-17
Synonyms name
- cytotoxic T-lymphocyte-associated protein 8
GenBank acession
- U32659
Locus

6p12.2
Discovery year

1993-10-25
Entrez gene record

3605
Pubmed identfication
- 8390535
RefSeq identity
- NM_002190
Classification
- Interleukins
VEGA ID

OTTHUMG00000014840
Locus Specific Databases
- LRG_1223

Identity

HGNC:6019
Gene

IL6R
Long gene name

interleukin 6 receptor
Synonyms
- CD126
- IL-6R
- IL-1Ra
- IL6RA
- gp80
Synonyms name
- membrane glycoprotein 80
- interleukin 6 receptor subunit alpha
GenBank acession
- X12830
Locus

1q21.3
Discovery year

2001-06-22
Entrez gene record

3570
Pubmed identfication
- 8428753
- 12633863
RefSeq identity
- NM_000565
Classification
- CD molecules
- Interleukin receptors
- Immunoglobulin like domain containing
VEGA ID

OTTHUMG00000036073

Name

Blotting, Western
Concept

Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
Tree numbers
- E05.196.401.143
- E05.301.300.096
- E05.478.566.320.200
- E05.601.262
- E05.601.470.320.200
Qualifiers

ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data