Sphingosine Kinase 2 antibody Long Form N Terminal HIS Tag - Active Enzyme
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Catalog numberX1840E
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PricePlease ask
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Size10 μg
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CategoryProteins & Peptides
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Long descriptionThe long form of sphingosine kinase 2 (Sphk2-L) is a species-specific isoform of the Sphk2 enzyme expressed in human but not in mouse. It is an N-terminal extended form of Sphk2, extended by 36 amino acids. It functions as expected, catalyzing the formation of sphingosine 1-phosphate from sphingosine, however it appears to have a decreased ability to inhibit DNA synthesis as compared to Sphk2-S (short form of Sphk2). Under normal cellular conditions, Sphk2-L does not appear to inhibit DNA synthesis, but under serum deprivation, SphK2-L translocates to the nucleus and accumlates. This accumlation may be involved in the cessation of cell proliferation or apoptosis depending on the cell type.
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Antibody come fromn/a
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Other descriptionProvided as solution in phosphate buffered saline with 0.08% sodium azide.
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Clonenot specified
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Antigen antibody binding interactionSphingosine Kinase 2 antibody Long Form N Terminal HIS Tag - Active Enzyme
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Antibody is raised inSf9 cells
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Antibody s reacts withHuman
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Antibody s reacts with these speciesThis antibody doesn't cross react with other species
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Antibody s specificityNo Data Available
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ApplicationStudy of enzyme kinetics, screening inhibitors, and selectivity profiling.
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Antibody s suited forBlocking peptide for use with SIAH1 antibodies (Cat. Nos. X1859P & X1864P).
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Storage-80ºC
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Relevant referencesno information yet
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Protein numbersee ncbi
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WarningsThis product is intended FOR RESEARCH USE ONLY, and FOR TESTS IN VITRO, not for use in diagnostic or therapeutic procedures involving humans or animals. This datasheet is as accurate as reasonably achievable, but Nordic-MUbio accepts no liability for any inaccuracies or omissions in this information.
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PropertiesIf you buy Antibodies supplied by nordc they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
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DescriptionEnzymes are cleaving the substrate. If the substrate is DNA they are called restriction enzymes. Activating enzymes will cut off the domain that is biological active to become functional.
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Conjugationhistidine
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French translationanticorps
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Gene target
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Gene symbolHAL, VIS1, AKR1B10, TRH-GTG1-1, TRH-GTG1-3, TRH-GTG2-1, TRH-GTG3-1, TRH-GTG1-2, TRH-GTG1-4, TRH-GTG1-5
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Short nameSphingosine Kinase 2 antibody Long Form N Terminal HIS Tag - Active Enzyme
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TechniqueAntibody, Enzyme, antibodies against human proteins, antibodies for, enzymes, Tags
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Isotypenot specified
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Labelunlabeled
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Alternative nameSphingosine phosphorylation catalyst 2 (antibody to-) large Form N Terminal histidine detection labelled - functionnal Enzyme
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Alternative techniqueantibodies, enzymes
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Gene info
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Identity
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Gene
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Long gene namehistidine ammonia-lyase
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Synonyms gene
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Locus
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Discovery year1988-08-31
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Entrez gene record
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VEGA ID
Gene info
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Identity
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Gene
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Long gene nameviral integration site 1
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Synonyms
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GenBank acession
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Locus
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Discovery year1992-11-25
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Entrez gene record
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Pubmed identfication
Gene info
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Identity
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Gene
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Long gene namealdo-keto reductase family 1 member B10
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Synonyms gene
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Synonyms gene name
- aldo-keto reductase family 1, member B10 (aldose reductase)
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Synonyms
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Synonyms name
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GenBank acession
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Locus
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Discovery year2000-08-24
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- Aldo-keto reductases
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VEGA ID
Gene info
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Identity
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Gene
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Long gene nametRNA-His (anticodon GTG) 1-1
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Synonyms gene
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Synonyms gene name
- transfer RNA histidine 4 (anticodon GUG)
- transfer RNA-His (GTG) 1-1
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Synonyms
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GenBank acession
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Locus
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Discovery year2008-08-21
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Entrez gene record
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Classification
- Cytoplasmic transfer RNAs
Gene info
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Identity
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Gene
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Long gene nametRNA-His (anticodon GTG) 1-3
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Synonyms gene
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Synonyms gene name
- transfer RNA histidine 9 (anticodon GUG)
- transfer RNA-His (GTG) 1-3
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Synonyms
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GenBank acession
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Locus
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Discovery year2008-08-29
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Entrez gene record
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Classification
- Cytoplasmic transfer RNAs
Gene info
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Identity
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Gene
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Long gene nametRNA-His (GTG) 2-1
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Synonyms gene
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Synonyms gene name
- transfer RNA histidine 11 (anticodon GUG)
- transfer RNA-His (GTG) 2-1
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Synonyms
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GenBank acession
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Locus
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Discovery year2008-08-29
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Entrez gene record
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Classification
- Low confidence cytoplasmic transfer RNAs
Gene info
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Identity
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Gene
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Long gene nametRNA-His (anticodon GTG) 3-1
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Synonyms gene
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Synonyms gene name
- transfer RNA histidine 8 (anticodon GUG)
- transfer RNA-His (GTG) 3-1
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Synonyms
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GenBank acession
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Locus
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Discovery year2008-08-29
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Entrez gene record
Gene info
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Identity
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Gene
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Long gene nametRNA-His (anticodon GTG) 1-2
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Synonyms gene
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Synonyms gene name
- transfer RNA histidine 10 (anticodon GUG)
- transfer RNA-His (GTG) 1-2
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Synonyms
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GenBank acession
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Locus
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Discovery year2008-08-29
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Entrez gene record
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Classification
- Cytoplasmic transfer RNAs
Gene info
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Identity
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Gene
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Long gene nametRNA-His (anticodon GTG) 1-4
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Synonyms gene
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Synonyms gene name
- transfer RNA histidine 7 (anticodon GUG)
- transfer RNA-His (GTG) 1-4
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Synonyms
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GenBank acession
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Locus
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Discovery year2008-08-29
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Entrez gene record
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Classification
- Cytoplasmic transfer RNAs
Gene info
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Identity
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Gene
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Long gene nametRNA-His (anticodon GTG) 1-5
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Synonyms gene
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Synonyms gene name
- transfer RNA histidine 3 (anticodon GUG)
- transfer RNA-His (GTG) 1-8
- transfer RNA-His (GTG) 1-5
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Synonyms
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GenBank acession
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Locus
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Discovery year2008-09-03
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Entrez gene record
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Classification
- Cytoplasmic transfer RNAs
MeSH Data
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Name
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ConceptScope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
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Tree numbers
- E05.196.401.143
- E05.301.300.096
- E05.478.566.320.200
- E05.601.262
- E05.601.470.320.200
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Qualifiersethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data