CRP (C11F2) Monoclonal Antibody, ALEXA FLUOR 350
#
-
Catalog numberbsm-0391M-A350
-
Price:
-
Size100ul
-
-
Long nameCRP (C11F2) Monoclonal Antibody, ALEXA FLUOR 350 Conjugated
-
Also known asAnti-CRPC MAb ALEXA FLUOR 350
-
CategoryConjugated Primary Antibodies
-
Conjugated withALEXA FLUOR® 350
-
Host OrganismMouse (Mus musculus)
-
Target AntigenCRPC
-
SpecificityThis is a highly specific antibody against CRPC.
-
ModificationUnmodified
-
Modification SiteNone
-
ClonalityMonoclonal
-
CloneC11F2
-
Concentration1ug per 1ul
-
Subcellular locationSecreted
-
SourceRecombinant CRP protein
-
Gene ID Number1401
-
Tested applicationsIF(IHC-P)
-
Recommended dilutionsIF(IHC-P)(1:50-200)
-
CrossreactivityHuman
-
Cross reactive species detailsDue to limited amount of testing and knowledge, not every possible cross-reactivity is known.
-
Background of the antigenC Reactive Protein is a major acute phase reactant synthesized primarily in the liver hepatocytes. It is a pentraxin (cyclic pentameric protein) compound of five identical nonglycosylated subunits of 206 amino acids each (m.w. 24 kDa), that are bound noncovalently to form the physiologic CRP molecule (m.w. 117.5 kDa). C Reactive Protein mediates activities associated with preimmune nonspecific host resistance. It is opsonic, an initiator of the classical complement cascade and an activator of monocytes/macrophages. CRP also binds to several nuclear components including chromatin, histones and snRNP, suggesting that it may play a role as a scavenger during cell necrosis. Studies have revealed that among other markers of inflammation, CRP shows the strongest association with cardiovascular events. Many clinical studies demonstrated that coronary mortality among patients with unstable angina and elevated CRP is significantly higher comparing with the patients without elevated CRP. Measurements of C reactive protein (hsCRP) in the patients with ischemic heart disease provide a novel method for detecting individuals at high risk of plaque rupture.
-
PurificationPurified by Protein G.
-
Storage conditionsStore this antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Keep refrigerated at 2 to 8 degrees Celcius for up to one year.
-
Excitation emission343nm/442nm
-
SynonymsC reactive protein pentraxin related; CRP; MGC88244; PTX 1; PTX1; C Reactive Protein.
-
PropertiesFor facs or microscopy Alexa 1 conjugate. Alexa Fluor 350 conjugates can be used in multi-color flow cytometry with FACS's equipped with a second red laser or red diode. If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies. ALEXA FLUOR they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
-
ConjugationAlexa Fluor, ALEXA FLUOR 350
-
GeneC reactive proteins are detected by anti-CRP antibodies supplied by GENTAUR.
-
AboutMonoclonals of this antigen are available in different clones. Each murine monoclonal anibody has his own affinity specific for the clone. Mouse monoclonal antibodies are purified protein A or G and can be conjugated to FITC for flow cytometry or FACS and can be of different isotypes.
-
French translationanticorps
-
Gene target
-
Gene symbolCRP, PPIAP10
-
Short nameAnti-CRPC
-
TechniqueAntibody, antibodies against human proteins, antibodies for, Monoclonals or monoclonal antibodies
-
IsotypeImmunoglobulin G (IgG)
-
LabelALEXA FLUOR 350
-
Alternative nameCRP (C11F2) Monoclonal Antibody, ALEXA FLUOR 350
-
Alternative techniqueantibodies
-
Alternative to gene targetC-reactive protein, pentraxin-related, PTX1, CRP and IDBG-103911 and ENSG00000132693 and 1401, protein homodimerization activity, Extracellular, Crp and IDBG-205690 and ENSMUSG00000037942 and 12944, CRP and IDBG-630749 and ENSBTAG00000013907 and 527553
-
Gene info
-
Identity
-
Gene
-
Long gene nameC-reactive protein
-
Synonyms gene name
- C-reactive protein, pentraxin-related
-
Synonyms
-
Synonyms name
-
GenBank acession
-
Locus
-
Discovery year2001-06-22
-
Entrez gene record
-
Pubmed identfication
-
RefSeq identity
-
Classification
- Short pentraxins
-
VEGA ID
Gene info
-
Identity
-
Gene
-
Long gene namepeptidylprolyl isomerase A pseudogene 10
-
Synonyms gene
-
Synonyms gene name
- peptidylprolyl isomerase A (cyclophilin A)-like 2
- peptidylprolyl isomerase (cyclophilin) pseudogene 10
-
Synonyms
-
Synonyms name
-
GenBank acession
-
Locus
-
Discovery year1998-10-12
-
Entrez gene record
-
Pubmed identfication
-
RefSeq identity
-
VEGA ID
MeSH Data
-
Name
-
ConceptScope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
-
Tree numbers
- E05.196.401.143
- E05.301.300.096
- E05.478.566.320.200
- E05.601.262
- E05.601.470.320.200
-
Qualifiersethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data