Anti-CRP (C11F2) Monoclonal, ALEXA Fluor 594

• Catalog number
  GENTObsm-0391M-A594
• Price
  Please ask
• Size
  100 microliters

• Type
  Conjugated Primary Antibody
• Conjugated with
  ALEXA FLUOR 594
• Host organism
  Mouse (Mus musculus)
• Target Protein Peptide
  CRPC
• Specificity
  Highly specific antibody against CRPC
• Modification
  Not modified
• Clonality
  Monoclonal Antibodies
• Clone
  C11F2
• Concentration
  1ug per 1ul
• Antigen Source
  Recombinant CRP protein
• Gene ID
  1401
• Applications
  IF(IHC-P)
• Applications with corresponding dilutions
  IF(IHC-P)(1:50-200)
• Cross Reactive species
  Human (Homo sapiens)
• Cross Reactive Species details
  No significant cross reactivity is observed
• Background information
  C Reactive Protein is a major acute phase reactant synthesized primarily in the liver hepatocytes. It is a pentraxin (cyclic pentameric protein) compound of five identical nonglycosylated subunits of 206 amino acids each (m.w. 24 kDa), that are bound noncovalently to form the physiologic CRP molecule (m.w. 117.5 kDa). C Reactive Protein mediates activities associated with preimmune nonspecific host resistance. It is opsonic, an initiator of the classical complement cascade and an activator of monocytes/macrophages. CRP also binds to several nuclear components including chromatin, histones and snRNP, suggesting that it may play a role as a scavenger during cell necrosis. Studies have revealed that among other markers of inflammation, CRP shows the strongest association with cardiovascular events. Many clinical studies demonstrated that coronary mortality among patients with unstable angina and elevated CRP is significantly higher comparing with the patients without elevated CRP. Measurements of C reactive protein (hsCRP) in the patients with ischemic heart disease provide a novel method for detecting individuals at high risk of plaque rupture.
• Purification method
  Purified by Protein G.
• Storage
  Aqueous buffered solution containing 100ug/ml BSA, 50% glycerol and 0.09% sodium azide. Store at 4°C for 12 months.
• Excitation emission
  590nm/617nm
• Synonyms
  C reactive protein pentraxin related; CRP; MGC88244; PTX 1; PTX1; C Reactive Protein.
• Alternative name 1
  CRP (C11F2) Monoclonal Antibody, ALEXA FLUOR® 594 Conjugated
• Alternative name 2
  CRP (C11F2) Monoclonal anti-, ALEXA FLUOR 594 Conjugated
• Advisory
  Cycles of freezing and thawing should be avoided as such cycles may denature the peptide chains of the antibody and reduce its affinity, specificity and reactivity. For antibodies in a liquid form or reconstituted lyophilized antibodies - small amounts of the soultion could be captured on the cap or the walls of the container. Right before use you could briefly centrifuge the vial to collect all of the solution on the bottom.
• Properties
  For facs or microscopy Alexa 1 conjugate.
• Conjugation
  Alexa Fluor, ALEXA FLUOR® 594
• Conjugated
  Alexa conjugate 1
• Description
  This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided. Antibody for research use.
• Gene
  C reactive proteins are detected by anti-CRP antibodies supplied by GENTAUR.
• About
  Monoclonals of this antigen are available in different clones. Each murine monoclonal anibody has his own affinity specific for the clone. Mouse monoclonal antibodies are purified protein A or G and can be conjugated to FITC for flow cytometry or FACS and can be of different isotypes.

• Gene target
  CRP   C11F2   Monoclonal  
• Gene symbol
  CRP, PPIAP10
• Short name
  Anti-CRP (C11F2) Monoclonal,
• Technique
  anti-, anti, antibody to, antibodies, Monoclonals or monoclonal antibodies
• Isotype
  Immunoglobulin G (IgG)
• Label
  ALEXA FLUOR 594
• Alternative name
  Antibody toCRP (C11F2) monoclonal, ALEXA Fluor 594
• Alternative technique
  antibodies
• Alternative to gene target
  C-reactive protein, pentraxin-related, PTX1, CRP and IDBG-103911 and ENSG00000132693 and 1401, protein homodimerization activity, Extracellular, Crp and IDBG-205690 and ENSMUSG00000037942 and 12944, CRP and IDBG-630749 and ENSBTAG00000013907 and 527553

Gene info

• Identity
  HGNC:2367
• Gene
  CRP
• Long gene name
  C-reactive protein
• Synonyms gene name
  • C-reactive protein, pentraxin-related
• Synonyms
  • PTX1
• Synonyms name
  • pentraxin 1
• GenBank acession
  • M11725
• Locus
  1q23.2
• Discovery year
  2001-06-22
• Entrez gene record
  1401
• Pubmed identfication
  • 3840479
  • 6857266
• RefSeq identity
  • NM_000567
• Classification
  • Short pentraxins
• VEGA ID
  OTTHUMG00000035344

Gene info

• Identity
  HGNC:9264
• Gene
  PPIAP10
• Long gene name
  peptidylprolyl isomerase A pseudogene 10
• Synonyms gene
  • PPIAL2
  • PPIP10
• Synonyms gene name
  • peptidylprolyl isomerase A (cyclophilin A)-like 2
  • peptidylprolyl isomerase (cyclophilin) pseudogene 10
• Synonyms
  • CRP
• Synonyms name
  • cyclophillin related pseudogene
• GenBank acession
  • AL354993
• Locus
  20q13.2
• Discovery year
  1998-10-12
• Entrez gene record
  140913
• Pubmed identfication
  • 9671742
• RefSeq identity
  • NG_001008
• VEGA ID
  OTTHUMG00000032762

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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