CRP (C11F2) Antibody, Biotin Conjugated

• Catalog number
  bsm-0391M-Biotin
• Price
  Please ask
• Size
  0.1ml

• Long name
  CRP (C11F2) Monoclonal Antibody, Biotin Conjugated
• Category
  Conjugated Primary Antibodies
• Conjugation
  Biotin
• Host Organism
  Mouse (Mus musculus)
• Target Antigen
  CRPC
• Specificity
  This is a highly specific antibody against CRPC.
• Modification
  Unmodified
• Modification site
  None
• Clonality
  Monoclonal
• Clone
  C11F2
• Concentration
  1ug per 1ul
• Subcellular location
  Secreted
• Source
  Recombinant CRP protein
• Gene ID number
  1401
• Tested applications
  WB, IHC-P
• Recommended dilutions
  WB(1:100-1000), IHC-P(1:100-500)
• Crossreactivity
  Human
• Crossreactive species details
  Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.
• Antigen background
  C Reactive Protein is a major acute phase reactant synthesized primarily in the liver hepatocytes. It is a pentraxin (cyclic pentameric protein) compound of five identical nonglycosylated subunits of 206 amino acids each (m.w. 24 kDa), that are bound noncovalently to form the physiologic CRP molecule (m.w. 117.5 kDa). C Reactive Protein mediates activities associated with preimmune nonspecific host resistance. It is opsonic, an initiator of the classical complement cascade and an activator of monocytes/macrophages. CRP also binds to several nuclear components including chromatin, histones and snRNP, suggesting that it may play a role as a scavenger during cell necrosis. Studies have revealed that among other markers of inflammation, CRP shows the strongest association with cardiovascular events. Many clinical studies demonstrated that coronary mortality among patients with unstable angina and elevated CRP is significantly higher comparing with the patients without elevated CRP. Measurements of C reactive protein (hsCRP) in the patients with ischemic heart disease provide a novel method for detecting individuals at high risk of plaque rupture.
• Purification method
  Purified by Protein G.
• Storage conditions
  Keep the antibody in an aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store refrigerated at 2 to 8 degrees Celcius for up to 1 year.
• Excitation Emission
  N/A
• Synonyms
  C reactive protein pentraxin related; CRP; MGC88244; PTX 1; PTX1; C Reactive Protein.
• Properties
  If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°C for long term storage and for short term at + 5°C. Biotin conjugates can be detected by horseradish peroxidase, alkaline phosphatase substrates or anti biotin conjugated antibodies. Avidin and Streptavidin bind to the small biotin and are couple to HRP or AP for ELISA. To break the streptavidin Biotin bond we suggest to use a 6 molar guanidine HCl solution with acidity of pH 1.6.
• Additional conjugation
  Biotinylated
• Gene
  C reactive proteins are detected by anti-CRP antibodies supplied by GENTAUR.
• French translation
  anticorps

• Gene target
  CRP   C11F2   Conjugated  
• Gene symbol
  CRP, PPIAP10
• Short name
  Anti-CRPC
• Technique
  Antibody, antibodies against human proteins, antibodies for, antibody Conjugates
• Isotype
  Immunoglobulin G (IgG)
• Label
  Biotin
• Alternative name
  Anti-CRPC MAb Biotin
• Alternative technique
  antibodies
• Alternative to gene target
  C-reactive protein, pentraxin-related, PTX1, CRP and IDBG-103911 and ENSG00000132693 and 1401, protein homodimerization activity, Extracellular, Crp and IDBG-205690 and ENSMUSG00000037942 and 12944, CRP and IDBG-630749 and ENSBTAG00000013907 and 527553

Gene info

• Identity
  HGNC:2367
• Gene
  CRP
• Long gene name
  C-reactive protein
• Synonyms gene name
  • C-reactive protein, pentraxin-related
• Synonyms
  • PTX1
• Synonyms name
  • pentraxin 1
• GenBank acession
  • M11725
• Locus
  1q23.2
• Discovery year
  2001-06-22
• Entrez gene record
  1401
• Pubmed identfication
  • 3840479
  • 6857266
• RefSeq identity
  • NM_000567
• Classification
  • Short pentraxins
• VEGA ID
  OTTHUMG00000035344

Gene info

• Identity
  HGNC:9264
• Gene
  PPIAP10
• Long gene name
  peptidylprolyl isomerase A pseudogene 10
• Synonyms gene
  • PPIAL2
  • PPIP10
• Synonyms gene name
  • peptidylprolyl isomerase A (cyclophilin A)-like 2
  • peptidylprolyl isomerase (cyclophilin) pseudogene 10
• Synonyms
  • CRP
• Synonyms name
  • cyclophillin related pseudogene
• GenBank acession
  • AL354993
• Locus
  20q13.2
• Discovery year
  1998-10-12
• Entrez gene record
  140913
• Pubmed identfication
  • 9671742
• RefSeq identity
  • NG_001008
• VEGA ID
  OTTHUMG00000032762

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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