a1-Antitrypsin (AAT, alpha1 Proteinase Inhibitor, alpha1 PI, native and denatured) Antibody
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Catalog numberGEN604011
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PricePlease ask
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Size100ul
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Also known asa1-Antitrypsin
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Other namesalpha-1-antitrypsin; Alpha-1-antitrypsin; alpha-1-antitrypsin; serpin A1; alpha-1-antiproteinase; alpha-1-antitrypsin null; alpha-1 protease inhibitor; protease inhibitor 1 (anti-elastase), alpha-1-antitrypsin; serine (or cysteine) proteinase inhibitor, clade A, member 1; serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1; Alpha-1 protease inhibitor; Alpha-1-antiproteinase; Serpin A1
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CategoryAntibodies
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SubcategoryMnoclonal antibodies
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Gene nameSERPINA1; SERPINA1; PI; A1A; AAT; PI1; A1AT; PRO2275; alpha1AT; AAT; PI; SPAAT
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Gene name synonimsSERPINA1; SERPINA1; PI; A1A; AAT; PI1; A1AT; PRO2275; alpha1AT; AAT; PI; SPAAT
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Other gene namesSERPINA1; SERPINA1; PI; A1A; AAT; PI1; A1AT; PRO2275; alpha1AT; AAT; PI; SPAAT
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ClonalityMonoclonal
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Immunoglobulin isotypeIgG1,k
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Clone6F5
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Host organismMouse (Mus musculus)
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Source organismHuman (Homo sapiens)
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Species reactivityHuman (Homo sapiens); Due to limited knowledge and inability for testing each and every species, the reactivity of the antibody may extend to other species which are not listed hereby.
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Specificity and cross reactivityRecognizes human a-1 AT, native and denatured. Epitope specificity differs from that of clone 6F4. Reacts strongly with a-1 AT. Strong reaction is seen in ELISA with native and denatured a-1 AT directly coated onto the microtiter well. When tested in sandwich ELISA in combination with a polyclonal antibody against a-1 AT, it only recognizes native a-1 AT. In Western Blot after SDS-PAGE, this antibody reacts with native and denatured a-1 AT in reduced as well as non-reduced forms.; Since it is not possible to test each and every species our knowledge on the corss reactivity of the antibodies is limited. This particular antibody might cross react with speacies outside of the listed ones.
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Purification methodAffinity Purified by Protein A/G affinity chromatography.
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Form AppearanceSupplied as a liquid in PBS, pH 7.2, 15mM sodium azide, before the addition of glycerol to 40%.
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ConcentrationN/A
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Storage and shippingStore the antibody at +4 degrees Celsius for short term storage.. Long-term storage should be done after aliquoting the antibody and freezing the aliqotes at -20 degrees Celsius. Under these conditions the aliquots will be stable for at least one year if kept at -20 °C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
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Tested applicationsELISA (EL/EIA), Western Blot (WB)
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PropertiesIf you buy Antibodies supplied by MBS Monoclonals they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
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DescriptionTissue, pathway, proteinase, peptidase, protease ,acrosin, lipoprotein, activator, caspase, trypsin, papain, esterase inhibitors are proteins or receptor ligands or receptor antagonists that bind to an enzyme receptor and decreases its activity. Since blocking an enzyme's activity can kill a pathogen or correct a metabolic imbalance, many drugs are enzyme inhibitors. Not all receptor antagonist that bind to enzymes are inhibitors; enzyme activator ligands or agonists bind to enzymes and increase their enzymatic activity, while enzyme substrates bind and are converted to products in the normal catalytic cycle of the enzyme.
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French translationanticorps
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Gene target
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Gene symbolTRI-AAT1-1, TRI-AAT4-1, TRI-AAT7-1, TRI-AAT3-1, TRI-AAT11-1, TRI-AAT7-2, TRI-AAT12-1, TRI-AAT2-1, TRI-AAT6-1, TRI-AAT8-1
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Short namea1-Antitrypsin (AAT, alpha1 Proteinase Inhibitor, alpha1 PI, native denatured) Antibody
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TechniqueAntibody, antibodies against human proteins, antibodies for
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Alternative nameAnti-a1-Antitrypsin (AAT, alpha1 Proteinase Inhibitor, alpha1 PI, native and denatured)
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Alternative techniqueantibodies
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Gene info
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Identity
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Gene
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Long gene nametRNA-Ile (anticodon AAT) 1-1
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Synonyms gene
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Synonyms gene name
- transfer RNA isoleucine 12 (anticodon AAU)
- transfer RNA-Ile (AAT) 1-1
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Synonyms
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GenBank acession
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Locus
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Discovery year2008-08-29
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Entrez gene record
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Classification
- Cytoplasmic transfer RNAs
Gene info
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Identity
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Gene
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Long gene nametRNA-Ile (anticodon AAT) 4-1
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Synonyms gene
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Synonyms gene name
- transfer RNA isoleucine 24 (anticodon AAU)
- transfer RNA-Ile (AAT) 4-1
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Synonyms
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GenBank acession
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Locus
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Discovery year2008-08-29
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Entrez gene record
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Classification
- Cytoplasmic transfer RNAs
Gene info
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Identity
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Gene
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Long gene nametRNA-Ile (anticodon AAT) 7-1
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Synonyms gene
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Synonyms gene name
- transfer RNA isoleucine 8 (anticodon AAU)
- transfer RNA-Ile (AAT) 7-1
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Synonyms
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GenBank acession
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Locus
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Discovery year2008-08-29
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Entrez gene record
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Classification
- Cytoplasmic transfer RNAs
Gene info
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Identity
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Gene
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Long gene nametRNA-Ile (anticodon AAT) 3-1
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Synonyms gene
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Synonyms gene name
- transfer RNA isoleucine 11 (anticodon AAU)
- transfer RNA-Ile (AAT) 3-1
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Synonyms
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GenBank acession
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Locus
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Discovery year2008-08-29
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Entrez gene record
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Classification
- Cytoplasmic transfer RNAs
Gene info
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Identity
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Gene
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Long gene nametRNA-Ile (anticodon AAT) 11-1
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Synonyms gene
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Synonyms gene name
- transfer RNA isoleucine 29 (anticodon AAU) pseudogene
- transfer RNA-Ile (AAT) 11-1
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Synonyms
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GenBank acession
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Locus
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Discovery year2008-08-29
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Entrez gene record
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RefSeq identity
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Classification
- Cytoplasmic transfer RNA pseudogenes
Gene info
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Identity
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Gene
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Long gene nametRNA-Ile (anticodon AAT) 7-2
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Synonyms gene
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Synonyms gene name
- transfer RNA isoleucine 25 (anticodon AAU)
- transfer RNA-Ile (AAT) 7-2
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Synonyms
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GenBank acession
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Locus
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Discovery year2008-08-29
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Entrez gene record
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Classification
- Cytoplasmic transfer RNAs
Gene info
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Identity
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Gene
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Long gene nametRNA-Ile (anticodon AAT) 12-1
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Synonyms gene
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Synonyms gene name
- transfer RNA isoleucine 30 (anticodon AAU) pseudogene
- transfer RNA-Ile (AAT) 12-1
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Synonyms
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GenBank acession
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Locus
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Discovery year2008-08-29
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Entrez gene record
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Classification
- Cytoplasmic transfer RNAs
Gene info
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Identity
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Gene
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Long gene nametRNA-Ile (anticodon AAT) 2-1
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Synonyms gene
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Synonyms gene name
- transfer RNA isoleucine 4 (anticodon AAU)
- transfer RNA-Ile (AAT) 2-1
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Synonyms
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GenBank acession
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Locus
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Discovery year2008-08-29
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Entrez gene record
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Classification
- Cytoplasmic transfer RNAs
Gene info
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Identity
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Gene
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Long gene nametRNA-Ile (anticodon AAT) 6-1
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Synonyms gene
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Synonyms gene name
- transfer RNA isoleucine 22 (anticodon AAU)
- transfer RNA-Ile (AAT) 6-1
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Synonyms
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GenBank acession
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Locus
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Discovery year2008-08-29
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Entrez gene record
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Classification
- Cytoplasmic transfer RNAs
Gene info
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Identity
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Gene
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Long gene nametRNA-Ile (anticodon AAT) 8-1
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Synonyms gene
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Synonyms gene name
- transfer RNA isoleucine 5 (anticodon AAU)
- transfer RNA-Ile (AAT) 8-1
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Synonyms
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GenBank acession
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Locus
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Discovery year2008-08-29
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Entrez gene record
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Classification
- Cytoplasmic transfer RNAs
MeSH Data
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Name
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ConceptScope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
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Tree numbers
- E05.196.401.143
- E05.301.300.096
- E05.478.566.320.200
- E05.601.262
- E05.601.470.320.200
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Qualifiersethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data