CD55 / DAF monoclonal antibody

• Catalog number
  A4-230-T025
• Price
  Please ask
• Size
  25 assays

• Long name
  Mouse Monoclonal Antibody against Human CD55 / DAF, Clone: MEM-118
• Antigen
  CD55
• Species reactivity
  Human (Homo sapiens), Non-Human (Homo sapiens) Primates
• Negative species reactivity
  at the time of upload there has been no data, please, contact us to obtain most recent information on species reactivity and cross reactivity
• Clonality
  Monoclonal Antibody (Mab)
• Clone
  MEM-118
• Applications
  FC, IP, IHC(P)
• Immunogen
  HPB-ALL human T cell line
• Format conjugation
  Alexa Fluor 488
• Specificity
  The antibody MEM-118 recognizes an epitope in SCR4 domain of CD55 (Decay accelerating factor, DAF), a 60-70 kDa glycosylphosphatidylinositol (GPI)-anchored single chain glycoprotein. CD55 is widely expressed on hematopoietic and on many non-hematopoietic cells; it is weakly present on NK cells.HLDA V; WS Code AS S016_x000D_
• Research area
  CD Antigens & MHC (Veterinary), CD and Related Antigens (Human)
• Storage buffer
  The reagent is provided in stabilizing Tris buffered saline (TBS) solution containing 15 mM sodium azide.
• Shipping and storage
  Mouse Monoclonal Antibody against Human CD55 / DAF, Clone: MEM-118 is transported on blue ice/ice packs and should be stored at temperatures between 1 and 5 degrees Celsius. Do not freeze! Avoid exposing the product to direct light, especially the conjugated antibodies as most conjugates are very sentitive to light.
• Background
  CD55 (decay-accelerating factor, DAF) is a GPI-anchored membrane glycoprotein that protects autologous cells from classical and alternative pathway of complement cascade. Bidirectional interactions between CD55 and CD97 are involved in T cell regulation and CD55 can still regulate complement when bound to CD97. In tumours, besides protection agains complement, CD55 promotes neoangiogenesis, tumorigenesis, invasiveness and evasion of apoptosis.
• Purity
  > 95% (by SDS-PAGE)
• Purification method
  Purified by affinity chromatography
• Datasheet
• References
  *Angelisová P, Drbal K, Horejsí V, Cerný J: Association of CD10/neutral endopeptidase 24.11 with membrane microdomains rich in glycosylphosphatidylinositol-anchored proteins and Lyn kinase. Blood. 1999 Feb 15;93(4):1437-9., *Leukocyte Typing V., Schlossman S. et al. (Eds.), Oxford University Press (1995).
• Properties
  If you buy Antibodies supplied by Exbio they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• About
  Monoclonals of this antigen are available in different clones. Each murine monoclonal anibody has his own affinity specific for the clone. Mouse monoclonal antibodies are purified protein A or G and can be conjugated to FITC for flow cytometry or FACS and can be of different isotypes.
• French translation
  anticorps

• Gene target
  CD55   DAF   monoclonal  
• Gene symbol
  CD55
• Short name
  Anti-CD55 / DAF Mab
• Technique
  Antibody, antibodies against human proteins, antibodies for, Monoclonals or monoclonal antibodies
• Host
  Mouse (Mus musculus)
• Isotype
  IgM
• Alternative name
  Mouse Monoclonal to CD55 / DAF
• Alternative technique
  antibodies
• Alternative to gene target
  CD55 molecule, decay accelerating factor for complement (Cromer blood group), CR and CROM and DAF and TC, CD55 and IDBG-106331 and ENSG00000196352 and 1604, lipid binding, Extracellular, CD55 and IDBG-629269 and ENSBTAG00000006984 and 518609

Gene info

• Identity
  HGNC:2665
• Gene
  CD55
• Long gene name
  CD55 molecule (Cromer blood group)
• Synonyms gene
  • DAF
• Synonyms gene name
  • decay accelerating factor for complement (CD55, Cromer blood group system)
  • CD55 molecule, decay accelerating factor for complement (Cromer blood group)
• Synonyms
  • CR
  • TC
  • CROM
• GenBank acession
  • BC001288
• Locus
  1q32.2
• Discovery year
  2001-06-22
• Entrez gene record
  1604
• RefSeq identity
  • NM_000574
• Classification
  • Blood group antigens
  • Complement system regulators and receptors
  • CD molecules
  • Sushi domain containing
• VEGA ID
  OTTHUMG00000036255
• Locus Specific Databases
  • Blood Group Antigen Mutation Database
  • CD55base: Mutation registry for Decay-accelerating factor (CD55) deficiency (previously known as DAFbase)
  • LRG_127

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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