CD55 / DAF monoclonal antibody
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Catalog number11-230-C025
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PricePlease ask
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Size25ug
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Long nameMouse Monoclonal Antibody against Human CD55 / DAF, Clone: MEM-118
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AntigenCD55
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Species reactivityHuman (Homo sapiens), Non-Human (Homo sapiens) Primates
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Negative species reactivityat the time of upload there has been no data, please, contact us to obtain most recent information on species reactivity and cross reactivity
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ClonalityMonoclonal Antibody (Mab)
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CloneMEM-118
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ApplicationsFC, IP, IHC(P)
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ImmunogenHPB-ALL human T cell line
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Format conjugationpurified; unconjugated
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SpecificityThe antibody MEM-118 recognizes an epitope in SCR4 domain of CD55 (Decay accelerating factor, DAF), a 60-70 kDa glycosylphosphatidylinositol (GPI)-anchored single chain glycoprotein. CD55 is widely expressed on hematopoietic and on many non-hematopoietic cells; it is weakly present on NK cells.HLDA V; WS Code AS S016_x000D_
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Research areaCD Antigens & MHC (Veterinary), CD and Related Antigens (Human)
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Concentration1 mg/ml
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Storage bufferTris buffered saline (TBS) with 15 mM sodium azide, approx. pH 8.0
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Shipping and storageMouse Monoclonal Antibody against Human CD55 / DAF, Clone: MEM-118 is transported on blue ice/ice packs and should be stored at temperatures between 1 and 5 degrees Celsius. Do not freeze! Avoid exposing the product to direct light, especially the conjugated antibodies as most conjugates are very sentitive to light.
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BackgroundCD55 (decay-accelerating factor, DAF) is a GPI-anchored membrane glycoprotein that protects autologous cells from classical and alternative pathway of complement cascade. Bidirectional interactions between CD55 and CD97 are involved in T cell regulation and CD55 can still regulate complement when bound to CD97. In tumours, besides protection agains complement, CD55 promotes neoangiogenesis, tumorigenesis, invasiveness and evasion of apoptosis.
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Purity> 95% (by SDS-PAGE)
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Purification methodPurified by precipitation and chromatography
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References*Angelisová P, Drbal K, Horejsí V, Cerný J: Association of CD10/neutral endopeptidase 24.11 with membrane microdomains rich in glycosylphosphatidylinositol-anchored proteins and Lyn kinase. Blood. 1999 Feb 15;93(4):1437-9., *Leukocyte Typing V., Schlossman S. et al. (Eds.), Oxford University Press (1995).
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PropertiesIf you buy Antibodies supplied by Exbio they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
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AboutMonoclonals of this antigen are available in different clones. Each murine monoclonal anibody has his own affinity specific for the clone. Mouse monoclonal antibodies are purified protein A or G and can be conjugated to FITC for flow cytometry or FACS and can be of different isotypes.
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French translationanticorps
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Gene target
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Gene symbolCD55
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Short nameAnti-CD55 / DAF Mab
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TechniqueAntibody, antibodies against human proteins, antibodies for, Monoclonals or monoclonal antibodies
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HostMouse (Mus musculus)
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IsotypeIgM
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Alternative nameMouse Monoclonal to CD55 / DAF
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Alternative techniqueantibodies
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Alternative to gene targetCD55 molecule, decay accelerating factor for complement (Cromer blood group), CR and CROM and DAF and TC, CD55 and IDBG-106331 and ENSG00000196352 and 1604, lipid binding, Extracellular, CD55 and IDBG-629269 and ENSBTAG00000006984 and 518609
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Gene info
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Identity
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Gene
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Long gene nameCD55 molecule (Cromer blood group)
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Synonyms gene
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Synonyms gene name
- decay accelerating factor for complement (CD55, Cromer blood group system)
- CD55 molecule, decay accelerating factor for complement (Cromer blood group)
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Synonyms
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GenBank acession
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Locus
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Discovery year2001-06-22
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Entrez gene record
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RefSeq identity
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Classification
- Blood group antigens
- Complement system regulators and receptors
- CD molecules
- Sushi domain containing
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VEGA ID
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Locus Specific Databases
MeSH Data
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Name
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ConceptScope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
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Tree numbers
- E05.196.401.143
- E05.301.300.096
- E05.478.566.320.200
- E05.601.262
- E05.601.470.320.200
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Qualifiersethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data