Recombinant Rat BAFFR / TNFRSF13C Protein (His tag) 100µg
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Catalog numberPKSR030342-100µg
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Price:
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Size100µg
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SynonymTNFRSF13C
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ActivityNA
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SequenceSer10-Ala71
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Fusion tagC-His
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AccessionD3ZNT3
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ExpressedHostHEK293 Cells
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ShippingIn general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature.Bulk packages of recombinant proteins are provided as frozen liquid. They are shipped out with blue ice unless customers require otherwise.
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Purity> 85 % as determined by SDS-PAGE
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Endotoxin< 1.0 EU per μg of the protein as determined by the LAL method
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Stability and StorageSamples are stable for up to twelve months from date of receipt at -70℃.Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Mol Mass8.3 kDa
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AP Mol Mass20 KDa
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FormulationLyophilized from sterile PBS, pH 7.4
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BackgroundTumor necrosis factor receptor superfamily, member 13C (TNFRSF13C) also known as B-cell-activating factor receptor (BAFFR) and CD268 antigen, is a member of the tumor necrosis factor receptor superfamily. A tumor necrosis factor receptor (TNFR), or death receptor, is a trimeric cytokine receptor that binds tumor necrosis factors (TNF). The receptor cooperates with an adaptor protein which is important in determining the outcome of the response. Members of the TNF receptor superfamily (TNFRSF) have crucial roles in both innate and adaptive immunity and in cellular apoptosis process. Apoptosis is a cell suicide mechanism that enables metazoans to control cell number in tissues and to eliminate individual cells that threaten the animal's survival. Certain cells have unique sensors, termed death receptors or tumour necrosis factor (TNFR), on their surface. Tumour necrosis factors (TNFR) detect the presence of extracellular death signals and, in response, they rapidly ignite the cell's intrinsic apoptosis machinery. It has been proposed that abnormally high levels of BAFFR/TNFRSF13C (CD268) may contribute to the pathogenesis of autoimmune diseases by enhancing the survival of autoreactive B cells.
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Conjugationhistidine
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AboutRats are used to make rat monoclonal anti mouse antibodies. There are less rat- than mouse clones however. Rats genes from rodents of the genus Rattus norvegicus are often studied in vivo as a model of human genes in Sprague-Dawley or Wistar rats.
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Latin nameRattus norvegicus
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SourceRecombinants or rec. proteins
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Grouprecombinants
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Gene target
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Gene symbolTNFRSF13C
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Short nameRecombinant BAFFR / TNFRSF13C Protein (His tag) 100µg
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TechniqueRecombinant, E. coli recombinant proteins are genetic recombinations in Escherichia coli, supplied as white sterile powder lyopillized. Elabscience advises they will be reconstituted in a buffer soluion or culture medium for cell culture. Tags
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HostRat
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LabelHis
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SpeciesRat, Rats
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Alternative nameRec. Rat BAFFR / tumor necrosis factor receptor superfamily, member 13C Protein (histidine detection labelled) 100µg
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Alternative techniquerec
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Alternative to gene targettumor necrosis factor receptor superfamily, member 13C, TNFRSF13C and IDBG-9491 and ENSG00000159958 and 115650, Cell surfaces, Tnfrsf13c and IDBG-166389 and ENSMUSG00000068105 and 72049, TNFRSF13C and IDBG-642017 and ENSBTAG00000026489 and 618516
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Gene info
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Identity
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Gene
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Long gene nameTNF receptor superfamily member 13C
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Synonyms gene name
- tumor necrosis factor receptor superfamily, member 13C
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Synonyms
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GenBank acession
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Locus
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Discovery year2002-05-22
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Entrez gene record
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Pubmed identfication
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Classification
- Tumor necrosis factor receptor superfamily
- CD molecules
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VEGA ID
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Locus Specific Databases
MeSH Data
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Name
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ConceptScope note: The initial culturing of cells derived directly from fresh TISSUES.
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Tree numbers
- E01.370.225.500.223.500
- E05.200.500.265.500
- E05.242.223.500
- E05.481.500.249.500
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Qualifiersethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data