Recombinant Rat CD83 Protein (His tag) 100µg
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Catalog number
PKSR030224-100µg
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Price
Please ask
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Size
100µg
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Synonym
CD83
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Activity
NA
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Sequence
Met1-Ala134
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Fusion tag
C-His
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Accession
B2GV95
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ExpressedHost
HEK293 Cells
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Shipping
In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature.Bulk packages of recombinant proteins are provided as frozen liquid. They are shipped out with blue ice unless customers require otherwise.
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Purity
> 95 % as determined by SDS-PAGE
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Endotoxin
< 1.0 EU per μg of the protein as determined by the LAL method
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Stability and Storage
Samples are stable for up to twelve months from date of receipt at -70℃.Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Mol Mass
13.9 kDa
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AP Mol Mass
28-32 KDa
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Formulation
Lyophilized from sterile PBS, pH 7.4
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Background
The cluster of differentiation (CD) system is commonly used as cell markers in immunophynotyping. Different kinds of cells in the immune system can be identified through the surface CD molecules which associating with the immune function of the cell. There are more than 320 CD unique clusters and subclusters have been identified. Some of the CD molecules serve as receptors or ligands important to the cell through initiating a signal cascade which then alter the behavior of the cell. Some CD proteins do not take part in cell signal process but have other functions such as cell adhesion. CD83 is considered as a marker of mature dendritic cells as well as an adhesion receptor that binds to resting monocytes and a subset of activated CD8+ T cells. In certain conditions, CD83 tended to dimerize or even multimerize through its aberrant intermolecular disulfide bonds. The injection of CD83-Ig can significantly enhaunce the rate of tumor growth and inhibit the T cell growth.
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Conjugation
histidine
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About
Rats are used to make rat monoclonal anti mouse antibodies. There are less rat- than mouse clones however. Rats genes from rodents of the genus Rattus norvegicus are often studied in vivo as a model of human genes in Sprague-Dawley or Wistar rats.
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Latin name
Rattus norvegicus
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Source
Recombinants or rec. proteins
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Group
recombinants
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Gene target
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Gene symbol
CD83
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Short name
Recombinant CD83 Protein (His tag) 100µg
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Technique
Recombinant, E. coli recombinant proteins are genetic recombinations in Escherichia coli, supplied as white sterile powder lyopillized. Elabscience advises they will be reconstituted in a buffer soluion or culture medium for cell culture. Tags
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Host
Rat
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Label
His
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Species
Rat, Rats
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Alternative name
Rec. Rat CD83 molecule Protein (histidine detection labelled) 100µg
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Alternative technique
rec
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Alternative to gene target
CD83 molecule, BL11 and HB15, CD83 and IDBG-62750 and ENSG00000112149 and 9308, protein binding, Cell surfaces, Cd83 and IDBG-147707 and ENSMUSG00000015396 and 12522, CD83 and IDBG-636028 and ENSBTAG00000031430 and 617034
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Gene info
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Identity
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Gene
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Long gene name
CD83 molecule
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Synonyms gene name
- CD83 antigen (activated B lymphocytes, immunoglobulin superfamily)
- CD83 molecule
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Synonyms
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GenBank acession
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Locus
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Discovery year
1999-03-26
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Entrez gene record
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Pubmed identfication
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Classification
- CD molecules
- V-set domain containing
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VEGA ID
Product images
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